Environmentally benign diastereoselective synthesis of granatane and tropane aldol derivatives

RSC Advances ◽  
2014 ◽  
Vol 4 (56) ◽  
pp. 29668 ◽  
Author(s):  
Aneta Nodzewska ◽  
Agnieszka Bokina ◽  
Katarzyna Romanowska ◽  
Ryszard Lazny
Keyword(s):  
Environmentally Benign ◽  
Diastereoselective Synthesis

Naturally Occurring Organic Acid-catalyzed Facile Diastereoselective Synthesis of Biologically Active (E)-3-(arylimino)indolin-2-one Derivatives in Water at Room Temperature

2019 ◽  
Vol 23 (16) ◽  
pp. 1778-1788 ◽  
Author(s):  
Gurpreet Kaur ◽  
Arvind Singh ◽  
Kiran Bala ◽  
Mamta Devi ◽  
Anjana Kumari ◽  
...  
Keyword(s):  
Room Temperature ◽  
Biologically Active ◽  
Environmentally Benign ◽  
Diastereoselective Synthesis ◽  
Substituted Anilines ◽  
Reaction Conditions ◽  
Naturally Occurring ◽  
Acid Catalyzed ◽  
Reaction Media ◽  
Column Chromatographic

A simple, straightforward and efficient method has been developed for the synthesis of (E)-3-(arylimino)indolin-2-one derivatives and (E)-2-((4-methoxyphenyl)imino)- acenaphthylen-1(2H)-one. The synthesis of these biologically-significant scaffolds was achieved from the reactions of various substituted anilines and isatins or acenaphthaquinone, respectively, using commercially available, environmentally benign and naturally occurring organic acids such as mandelic acid or itaconic acid as catalyst in aqueous medium at room temperature. Mild reaction conditions, energy efficiency, good to excellent yields, environmentally benign conditions, easy isolation of products, no need of column chromatographic separation and the reusability of reaction media are some of the significant features of the present protocol.

scholarly journals Environmentally benign and diastereoselective synthesis of 2,4,5-trisubstituted-2-imidazolines

RSC Advances ◽  
2017 ◽  
Vol 7 (84) ◽  
pp. 53278-53289 ◽  
Author(s):  
Hai Anh Le Phuong ◽  
Levente Cseri ◽  
George F. S. Whitehead ◽  
Arthur Garforth ◽  
Peter Budd ◽  
...  
Keyword(s):  
Reaction Kinetics ◽  
Substituent Effects ◽  
Kinetics And Mechanism ◽  
Environmentally Benign ◽  
Diastereoselective Synthesis ◽  
One Pot

A one-pot, membrane-assisted synthesis of 2,4,5-trisubstituted-2-imidazolines was developed, and substituent effects, reaction kinetics and mechanism by DFT were studied.

Theophylline as the catalyst for the diastereoselective synthesis of trans-1,2-dihydrobenzo[a]furo[2,3-c]phenazines in water

RSC Advances ◽  
2016 ◽  
Vol 6 (87) ◽  
pp. 84326-84333 ◽  
Author(s):  
Afshin Yazdani-Elah-Abadi ◽  
Razieh Mohebat ◽  
Malek-Taher Maghsoodlou
Keyword(s):  
Environmentally Benign ◽  
Domino Reaction ◽  
Diastereoselective Synthesis ◽  
Reaction In Water ◽  
Pyridinium Ylide

Theophylline-catalyzed efficient and environmentally benign procedure for the diastereoselective synthesis of trans-1,2-dihydrobenzo[a]furo[2,3-c]phenazines with pyridinium ylide assisted domino reaction in water.

Copper-catalyzed non-directed hydrosilylation of cyclopropenes: highly diastereoselective synthesis of fully substituted cyclopropylsilanes

2020 ◽  
Vol 56 (12) ◽  
pp. 1819-1822 ◽  
Author(s):  
Hui Wang ◽  
Ge Zhang ◽  
Qian Zhang ◽  
Ying Wang ◽  
Yanfei Li ◽  
...  
Keyword(s):  
Base Metal ◽  
Environmentally Benign ◽  
Diastereoselective Synthesis ◽  
Metal Catalysis ◽  
Earth Abundant

The non-directed hydrosilylation of cyclopropenes with earth-abundant and environmentally benign base metal catalysis was described.

An environmentally benign double Michael addition reaction of heterocyclic ketene aminals with quinone monoketals for diastereoselective synthesis of highly functionalized morphan derivatives in water

2017 ◽  
Vol 19 (15) ◽  
pp. 3574-3584 ◽  
Author(s):  
Yu-Lu Ma ◽  
Kai-Min Wang ◽  
Rong Huang ◽  
Jun Lin ◽  
Sheng-Jiao Yan
Keyword(s):  
Michael Addition ◽  
Addition Reaction ◽  
Environmentally Benign ◽  
Diastereoselective Synthesis ◽  
Michael Addition Reaction ◽  
One Pot ◽  
Ketene Aminals

This effort involved an efficient and concise one-pot procedure for the synthesis of morphans based on quinone monoketals 1 reacting with HKAs 2.

scholarly journals Trifluoromethyl syn- or anti-γ-amino alcohols by one-pot solvent-free Mannich-type reactions under temperature control

RSC Advances ◽  
2015 ◽  
Vol 5 (37) ◽  
pp. 29312-29318 ◽  
Author(s):  
Stefania Fioravanti ◽  
Luca Parise ◽  
Alessia Pelagalli ◽  
Lucio Pellacani ◽  
Laura Trulli
Keyword(s):  
Temperature Control ◽  
Strong Influence ◽  
Amino Alcohols ◽  
Solvent Free ◽  
Environmentally Benign ◽  
Diastereoselective Synthesis ◽  
Reaction Conditions ◽  
One Pot

A highly diastereoselective synthesis of fluorinated syn- or anti-γ-amino alcohols was reported by a simple and environmentally benign methodology. Unexpectedly, a strong influence of the reaction conditions on the facial selective attack was found.

Diastereoselective Synthesis of Novel Optically Active Five Membered O- and N-heterocyclic Compounds

2012 ◽  
Vol 9 (2) ◽  
pp. 81-88 ◽  
Author(s):  
Ervin Kovacs ◽  
Ferenc Farkas ◽  
Angelika Thurner ◽  
Aron Szollosy ◽  
Ferenc Faigl
Keyword(s):  
Heterocyclic Compounds ◽  
Optically Active ◽  
Diastereoselective Synthesis
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