Delocalization of electronic states in graphene oxide stabilised mesoporous silica nanoparticles revealed using photoluminescence

RSC Advances ◽  
2014 ◽  
Vol 4 (34) ◽  
pp. 17879-17883 ◽  
Author(s):  
Naveen Chandrasekaran ◽  
Santhana Sivabalan ◽  
Aswin Prathap ◽  
S. Mohan ◽  
R. Jagannathan
Keyword(s):  
Graphene Oxide ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Silica Aerogel ◽  
Mesoporous Silica Nanoparticles ◽  
Sol Gel ◽  
Electronic States ◽  
Coordination Complexes ◽  
Sol Gel Process ◽  
Graphene Oxide Sheets

Mesoporous silica aerogel obtained through a sol–gel process when surface treated with 2-D graphene oxide sheets reveals many fascinating features particularly, leading to multiple coordination complexes based on amide linkages.

Green Synthesis of AgNPs Coated Mesoporous Silica Nanoparticles Using Tyrosine as Reducing/Stabilising Agent

2018 ◽  
Vol 928 ◽  
pp. 89-93 ◽  
Author(s):  
Waranya Ratirotjanakul ◽  
Tanapon Sioloetwong ◽  
Teeraporn Suteewong ◽  
Pramuan Tangboriboonrat
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
High Speed ◽  
Mesoporous Silica Nanoparticles ◽  
Drug Carrier ◽  
Sol Gel ◽  
Visible Absorption ◽  
Sol Gel Process ◽  
Phenolic Group ◽  
Uv Visible

A novel, simple and environmental friendly approach to fabricate silver nanoparticles (AgNPs) on mesoporous silica nanoparticles (MSNs) using tyrosine (Tyr) as biological reducing agent was developed. The functionalization of Tyr with MSNs (Tyr-MSNs) (150 nm in length) by the sol-gel process was confirmed by the characteristic peaks of amino, carboxyl and silanol groups appeared in FTIR spectrum and the change of the zeta potential from 0 mV at pH 2 to-60 mV at pH 12. Then, AgNPs were formed on the surface of Tyr-MSNs (Tyr-MSN@AgNPs) via only reducibility from phenolic group of Tyr and catalytic activity from base at room temperature. TEM images and UV-Visible absorption band at 420 nm supported the obtained AgNPs (18 nm at pH 11) were tightly bound to Tyr-MSNs even after centrifugation at high speed. These Tyr-MSN@AgNPs would be potentially used as drug carrier in biomedical applications.

scholarly journals A flexible smart membrane consisting of GO composite fibres and upconversion MSNs for microRNA detection

2019 ◽  
Vol 55 (62) ◽  
pp. 9104-9107 ◽  
Author(s):  
Tongxu Gu ◽  
Zhaohui Ren ◽  
Xiang Li ◽  
Jie Huang ◽  
Gaorong Han
Keyword(s):  
Graphene Oxide ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Dna Probes ◽  
Single Stranded Dna ◽  
Microrna Detection ◽  
Flexible Polyurethane

We have developed a photoluminescent membrane for microRNA detection, consisting of mesoporous silica nanoparticles (CaF2:Yb/Ho@MSNs) attached, via single stranded DNA probes, to flexible polyurethane fibres coated with graphene oxide (GO).

scholarly journals Large Pore Mesoporous Silica and Organosilica Nanoparticles for Pepstatin A Delivery in Breast Cancer Cells

Molecules ◽  
2019 ◽  
Vol 24 (2) ◽  
pp. 332 ◽  
Author(s):  
Saher Rahmani ◽  
Jelena Budimir ◽  
Mylene Sejalon ◽  
Morgane Daurat ◽  
Dina Aggad ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Cancer Cells ◽  
Cathepsin D ◽  
Breast Cancer Cells ◽  
Potent Inhibitor ◽  
Mesoporous Silica Nanoparticles ◽  
Sol Gel ◽  
Pepstatin A

(1) Background: Nanomedicine has recently emerged as a new area of research, particularly to fight cancer. In this field, we were interested in the vectorization of pepstatin A, a peptide which does not cross cell membranes, but which is a potent inhibitor of cathepsin D, an aspartic protease particularly overexpressed in breast cancer. (2) Methods: We studied two kinds of nanoparticles. For pepstatin A delivery, mesoporous silica nanoparticles with large pores (LPMSNs) and hollow organosilica nanoparticles (HOSNPs) obtained through the sol–gel procedure were used. The nanoparticles were loaded with pepstatin A, and then the nanoparticles were incubated with cancer cells. (3) Results: LPMSNs were monodisperse with 100 nm diameter. HOSNPs were more polydisperse with diameters below 100 nm. Good loading capacities were obtained for both types of nanoparticles. The nanoparticles were endocytosed in cancer cells, and HOSNPs led to the best results for cancer cell killing. (4) Conclusions: Mesoporous silica-based nanoparticles with large pores or cavities are promising for nanomedicine applications with peptides.

Reduced graphene oxide gated mesoporous silica nanoparticles as a versatile chemo-photothermal therapy system through pH controllable release

2015 ◽  
Vol 3 (30) ◽  
pp. 6377-6384 ◽  
Author(s):  
Ting Ting Wang ◽  
Jing Lan ◽  
Yue Zhang ◽  
Zhu Lian Wu ◽  
Chun Mei Li ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Graphene Oxide ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Reduced Graphene Oxide ◽  
Photothermal Therapy ◽  
Mesoporous Silica Nanoparticles ◽  
Reduced Graphene ◽  
Controllable Release ◽  
Acidic Environments

A multifunctional drug delivery system involving coupling photothermal therapy and chemotherapy together was developed, which based on the combination of rGO and MSNs, wherein the cargo molecules could be released in acidic environments due to the cleavage of the CN bond of Schiff bases.

scholarly journals An aptamer-targeting photoresponsive drug delivery system using “off–on” graphene oxide wrapped mesoporous silica nanoparticles

Nanoscale ◽  
2015 ◽  
Vol 7 (14) ◽  
pp. 6304-6310 ◽  
Author(s):  
Yuxia Tang ◽  
Hao Hu ◽  
Molly Gu Zhang ◽  
Jibin Song ◽  
Liming Nie ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Graphene Oxide ◽  
Cancer Therapy ◽  
Drug Release ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Drug Delivery System ◽  
Delivery System ◽  
Mesoporous Silica Nanoparticles ◽  
Targeted Cancer Therapy

A photoresponsive drug delivery system was developed for light-mediated drug release and aptamer-targeted cancer therapy.

A new method for loading mesoporous silica nanoparticles with drugs: Sol–gel synthesis using drug micelles as a template

2016 ◽  
Vol 78 (5) ◽  
pp. 586-595 ◽  
Author(s):  
O. V. Dement’eva ◽  
I. N. Senchikhin ◽  
M. E. Kartseva ◽  
V. A. Ogarev ◽  
A. V. Zaitseva ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Sol Gel ◽  
New Method ◽  
Sol Gel Synthesis
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