Rational design of drug-eluting stents via electrospray and in vivo evaluation of preventing oesophageal stricture

RSC Advances ◽  
2014 ◽  
Vol 4 (32) ◽  
pp. 16885-16892 ◽  
Author(s):  
Lili Zhao ◽  
Ying Gao ◽  
Guoxiang Gu ◽  
Jinhui Wu ◽  
Zhining Fan ◽  
...  
Keyword(s):  
Rational Design ◽  
Drug Eluting Stents ◽  
Oesophageal Stricture ◽  
In Vivo Evaluation ◽  
Drug Eluting

In Vivo Evaluation of the Synergic Effect of Metformin and mTOR Inhibitors on the Endothelial Healing of Drug-eluting Stents in Diabetic Patients

2018 ◽  
Vol 71 (11) ◽  
pp. 917-925
Author(s):  
Héctor Cubero-Gallego ◽  
Rafael Romaguera ◽  
Josep Gómez-Lara ◽  
Joan A. Gómez-Hospital ◽  
Manel Sabaté ◽  
...  
Keyword(s):  
Mtor Inhibitors ◽  
Drug Eluting Stents ◽  
Diabetic Patients ◽  
Synergic Effect ◽  
In Vivo Evaluation ◽  
Drug Eluting

In vivo evaluation of a pro-healing polydopamine coated stent through an in-stent restenosis rat model

2021 ◽  
Vol 9 (1) ◽  
pp. 212-220
Author(s):  
Adrien Hertault ◽  
Feng Chai ◽  
Mickael Maton ◽  
Jonathan Sobocinski ◽  
Patrice Woisel ◽  
...  
Keyword(s):  
Rat Model ◽  
Drug Eluting Stents ◽  
In Vivo Evaluation ◽  
Acute Thrombosis ◽  
Stent Restenosis ◽  
Drug Eluting ◽  
In Stent Restenosis

Drug-eluting stents have demonstrated efficiency in in-stent restenosis (ISR) but induced a risk of late acute thrombosis by delaying strut re-endothelialization.

Irinotecan drug eluting beads for use in chemoembolization: In vitro and in vivo evaluation of drug release properties

2007 ◽  
Vol 30 (1) ◽  
pp. 7-14 ◽  
Author(s):  
Rachel R. Taylor ◽  
Yiqing Tang ◽  
M. Victoria Gonzalez ◽  
Peter W. Stratford ◽  
Andrew L. Lewis
Keyword(s):  
Drug Release ◽  
In Vivo Evaluation ◽  
Drug Eluting Beads ◽  
Drug Eluting

In vivo evaluation of a biolimus eluting nickel titanium self expanding stent with overlapping balloon expandable drug eluting and bare metal stents in a porcine coronary model

2009 ◽  
Vol 4 (4) ◽  
pp. 534-541 ◽  
Author(s):  
Mehmet Cilingiroglu ◽  
James Elliott ◽  
Pramod Sangi ◽  
Holly Matthews ◽  
Fermin Tio ◽  
...  
Keyword(s):  
Bare Metal Stents ◽  
Nickel Titanium ◽  
Metal Stents ◽  
Bare Metal ◽  
In Vivo Evaluation ◽  
Drug Eluting

Drug-Eluting Stents Ameliorate Pulmonary Vein Stenotic Changes in Pigs In Vivo

2010 ◽  
Vol 31 (6) ◽  
pp. 773-779 ◽  
Author(s):  
Takeshi Furukawa ◽  
Masahiko Kishiro ◽  
Hideo Fukunaga ◽  
Masahiro Ohtsuki ◽  
Ken Takahashi ◽  
...  
Keyword(s):  
Pulmonary Vein ◽  
Drug Eluting Stents ◽  
Drug Eluting

Local insulin application on the carotid artery inhibits neointima formation

2013 ◽  
Vol 91 (12) ◽  
pp. 1086-1094 ◽  
Author(s):  
Simon Chiang ◽  
Danna M. Breen ◽  
June Guo ◽  
Yusaku Mori ◽  
Adria Giacca
Keyword(s):  
Carotid Artery ◽  
Insulin Treatment ◽  
Arterial Injury ◽  
Drug Eluting Stents ◽  
Late Stent Thrombosis ◽  
Vascular Effect ◽  
Smooth Muscle Cell Migration ◽  
Drug Eluting ◽  
New Treatments

Anti-mitogenic agents currently used to prevent restenosis in drug-eluting stents delay re-endothelialization. Delayed re-endothelialization is now considered as the main cause of late stent thrombosis with drug-eluting stents, which emphasizes the need for new treatments. We have shown that systemic insulin treatment decreases neointimal growth and accelerates re-endothelialization after arterial injury in a rat model of restenosis. However, systemic insulin treatment cannot be given to non-diabetic individuals because of the risk of hypoglycemia. Thus, we investigated whether local insulin treatment is also effective in reducing neointimal growth after arterial injury. Rats were given local vehicle or local insulin delivered via Pluronic gel applied around the carotid artery immediately following balloon injury. Plasma glucose and systemic insulin levels were not affected by local insulin treatment. Insulin decreased intimal area at 28 days (P < 0.05) and also inhibited vascular smooth muscle cell migration by 60% at 4 days (P < 0.05). NPH (a longer-lasting insulin) also decreased neointimal area. These results indicate that local insulin treatment can lead to decreased restenosis, suggesting a protective vascular effect of insulin in vivo and that local insulin treatment, possibly via insulin-eluting stents, may be clinically relevant.

Rational design, synthesis, and in vivo evaluation of the antileukemic activity of six new alkylating steroidal esters

2008 ◽  
Vol 16 (9) ◽  
pp. 5207-5215 ◽  
Author(s):  
Anna I. Koutsourea ◽  
Manolis A. Fousteris ◽  
Evagelia S. Arsenou ◽  
Athanasios Papageorgiou ◽  
George N. Pairas ◽  
...  
Keyword(s):  
Rational Design ◽  
Antileukemic Activity ◽  
In Vivo Evaluation ◽  
Design Synthesis

scholarly journals 255 In vivo detection of non-occlusive thrombi in drug-eluting stents by scintigraphy and radio-labelled annexin V in a rabbit model

2011 ◽  
Vol 3 (1) ◽  
pp. 84
Author(s):  
Francis Blackwell ◽  
Anne Meddahi-Pellé ◽  
Graciella Pavon-Djavid ◽  
François Rouzet ◽  
Liliane Louedec ◽  
...  
Keyword(s):  
Rabbit Model ◽  
Annexin V ◽  
Drug Eluting Stents ◽  
In Vivo Detection ◽  
Drug Eluting
Sign in / Sign up

Export Citation Format

Share Document