Facile fabrication of nanocomposite microcapsules by combining layer-by-layer self-assembly and Pickering emulsion templating

RSC Advances ◽  
2014 ◽  
Vol 4 (32) ◽  
pp. 16751-16758 ◽  
Author(s):  
Hao Liu ◽  
Xiaoyu Gu ◽  
Meng Hu ◽  
Yang Hu ◽  
Chaoyang Wang

Nanocomposite multilayer microcapsules are prepared by layer-by-layer self-assembly based on Pickering emulsions.

2019 ◽  
Vol 476 ◽  
pp. 501-512 ◽  
Author(s):  
Lehao Liu ◽  
Meicheng Li ◽  
Lihua Chu ◽  
Bing Jiang ◽  
Ruoxu Lin

2020 ◽  
Vol 515 ◽  
pp. 146063 ◽  
Author(s):  
Yirong Xiao ◽  
Dongxue Guo ◽  
Tong Li ◽  
Qingfeng Zhou ◽  
Liguo Shen ◽  
...  

2021 ◽  
Vol 8 ◽  
Author(s):  
Chong-hao Bi ◽  
Shang-yi Chi ◽  
Tong Zhou ◽  
Xue-ying Wang ◽  
Jia-yi Zhang ◽  
...  

In this paper, a novel high-internal-phase Pickering emulsion (HIPPE) prepared by acid-induced self-assembly SPI gel (A/S-SPIG) was investigated. The steady-state shear test results showed that all HIPPEs were typical shear thinning emulsion, which could form stable emulsion (0.2–1.2% SPI concentration). The network structure of HIPPE stabilized by A/S-SPIG particles (0.2–1.2% SPI concentration) was continuously enhanced with increasing SPI concentration. The high concentration of SPI particles increased the crystallization temperature of the stabilized HIPPE. Meanwhile, at a concentration of 1.2%, HIPPE has the best cohesive property and stability against delamination due to weakened mobility. In conclusion, A/S-SPIG was proved excellent HIPPE stabilized particle.


Nanomaterials ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 1884
Author(s):  
Mengfei Jin ◽  
Shangyong Li ◽  
Yanhong Wu ◽  
Dandan Li ◽  
Yantao Han

(1) Background: In the treatment of ulcerative colitis (UC), accurate delivery and release of anti-inflammatory drugs to the site of inflammation can reduce systemic side effects. (2) Methods: We took advantage of this goal to prepare resveratrol-loaded PLGA nanoparticles (RES-PCAC-NPs) by emulsification solvent volatilization. After layer-by-layer self-assembly technology, we deposited chitosan and alginate to form a three-layer polyelectrolyte film. (3) Results: It can transport nanoparticles through the gastric environment to target inflammation sites and slowly release drugs at a specific pH. The resulting RES-PCAC-NPs have an ideal average diameter (~255 nm), a narrow particle size distribution and a positively charged surface charge (~13.5 mV). The Fourier transform infrared spectroscopy showed that resveratrol was successfully encapsulated into PCAC nanoparticles, and the encapsulation efficiency reached 87.26%. In addition, fluorescence imaging showed that RES-PCAC-NPs with positive charges on the surface can effectively target and accumulate in the inflammation site while continuing to penetrate downward to promote mucosal healing. Importantly, oral RES-PCAC-NPs treatment in DSS-induced mice was superior to other results in significantly improved inflammatory markers of UC. (4) Conclusions: Our results strongly prove that RES-PCAC-NPs can target the inflamed colon for maximum efficacy, and this oral pharmaceutical formulation can represent a promising formulation in the treatment of UC.


Author(s):  
Haisheng Xie ◽  
Wenyu Zhao ◽  
Daniel Chikere Ali ◽  
Xuehong Zhang ◽  
Zhilong Wang

The Pickering emulsion interface is an exceptional habitat for bacteria to grow by simultaneously utilizing hydrophobic and hydrophilic chemicals.


2014 ◽  
Vol 14 (2) ◽  
pp. 1145-1153 ◽  
Author(s):  
Bing Yu ◽  
Xiaomian Liu ◽  
Hailin Cong ◽  
Hua Yuan ◽  
Dong Wang ◽  
...  
Keyword(s):  

2010 ◽  
Vol 46 (9) ◽  
pp. 1434 ◽  
Author(s):  
Meng Yang ◽  
Shanfu Lu ◽  
Jinlin Lu ◽  
San Ping Jiang ◽  
Yan Xiang

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