Cylindrical nanocapsules from photo-cross-linkable core–shell bottlebrush copolymers

2015 ◽  
Vol 6 (5) ◽  
pp. 764-771 ◽  
Author(s):  
Sebla Onbulak ◽  
Javid Rzayev
Keyword(s):  
Cross Linking ◽  
Core Shell ◽  
Metal Free ◽  
Grafting From

Coumarin-based, photo-cross-linkable core–shell bottlebrush copolymers were synthesized by a grafting-from approach. Hollow cylindrical nanocapsules were generated by selective, metal-free shell photo-cross-linking followed by hydrolytic core removal.

Characterization of Fe3O4@CS@NMDP magnetic nanoparticles with core–shell structure prepared by chemical cross-linking method

2017 ◽  
Vol 10 (05) ◽  
pp. 1750056 ◽  
Author(s):  
Huiping Shao ◽  
Jiangcong Qi ◽  
Tao Lin ◽  
Yuling Zhou ◽  
Fucheng Yu
Keyword(s):  
Magnetic Nanoparticles ◽  
Shell Structure ◽  
High Performance ◽  
Cross Linking ◽  
Composite Particles ◽  
Core Shell ◽  
The Core ◽  
Targeting Delivery ◽  
Core Shell Structure ◽  
Chemical Cross Linking

The core–shell structure composite magnetic nanoparticles (NPs), Fe3O4@chitosan@nimodipine (Fe3O4@CS@NMDP), were successfully synthesized by a chemical cross-linking method in this paper. NMDP is widely used for cardiovascular and cerebrovascular disease prevention and treatment, while CS is of biocompatibility. The composite particles were characterized by an X-ray diffractometer (XRD), a Fourier transform infrared spectroscopy (FT-IR), a transmission electron microscopy (TEM), a vibrating sample magnetometers (VSM) and a high performance liquid chromatography (HPLC). The results show that the size of the core–shell structure composite particles is ranging from 12[Formula: see text]nm to 20[Formula: see text]nm and the coating thickness of NMDP is about 2[Formula: see text]nm. The saturation magnetization of core–shell composite NPs is 46.7[Formula: see text]emu/g, which indicates a good potential application for treating cancer by magnetic target delivery. The release percentage of the NMDP can reach 57.6% in a short time of 20[Formula: see text]min in the PBS, and to 100% in a time of 60[Formula: see text]min, which indicates the availability of Fe3O4@CS@NMDP composite NPs for targeting delivery treatment.

Self-assembled dual-drug loaded core-shell nanoparticles based on metal-free fully alternating polyester for cancer theranostics

2019 ◽  
Vol 101 ◽  
pp. 448-463 ◽  
Author(s):  
Piyush Kumar Gupta ◽  
Sreenath Pappuru ◽  
Santosh Gupta ◽  
Bamadeb Patra ◽  
Debashis Chakraborty ◽  
...  
Keyword(s):  
Core Shell ◽  
Shell Nanoparticles ◽  
Metal Free ◽  
Self Assembled ◽  
Cancer Theranostics ◽  
Core Shell Nanoparticles ◽  
Dual Drug
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