Harmony of CdI2with CuBr for the one-pot synthesis of optically active α-allenols
2015 ◽
Vol 13
(13)
◽
pp. 4080-4089
◽
Keyword(s):
One Pot
◽
A highly efficient one-pot synthesis of chiral α-allenols from propargylic alcohols, aldehydes and pyrrolidine induced by CuBr and (R,Ra)-N-PINAP or (R,Sa)-N-PINAP and CdI2has been developed.