Asymmetric Michael addition of α-fluoro-α-nitro esters to nitroolefins: towards synthesis of α-fluoro-α-substituted amino acids

Jacek Kwiatkowski; Yixin Lu

doi:10.1039/c4ob02486a

Asymmetric Michael addition of α-fluoro-α-nitro esters to nitroolefins: towards synthesis of α-fluoro-α-substituted amino acids

Organic & Biomolecular Chemistry ◽

10.1039/c4ob02486a ◽

2015 ◽

Vol 13 (8) ◽

pp. 2350-2359 ◽

Cited By ~ 19

Author(s):

Jacek Kwiatkowski ◽

Yixin Lu

Keyword(s):

Amino Acids ◽

Michael Addition ◽

Asymmetric Michael Addition ◽

Nitro Esters ◽

Excellent Chemical

α-Fluoro-α-nitro esters were used as reaction partners in Michael addition to nitroalkenes, and the products were obtained in excellent chemical yields and with high enantioselectivities.

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ChemInform Abstract: Asymmetric Michael Addition of α-Fluoro-α-Nitro Esters to Nitroolefins: Towards Synthesis of α-Fluoro-α-Substituted Amino Acids.

ChemInform ◽

10.1002/chin.201526093 ◽

2015 ◽

Vol 46 (26) ◽

pp. no-no

Author(s):

Jacek Kwiatkowski ◽

Yixin Lu

Keyword(s):

Amino Acids ◽

Michael Addition ◽

Asymmetric Michael Addition ◽

Nitro Esters

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ChemInform Abstract: Highly Enantioselective Synthesis of α-Fluoro-α-nitro Esters via Organocatalyzed Asymmetric Michael Addition.

ChemInform ◽

10.1002/chin.201116056 ◽

2011 ◽

Vol 42 (16) ◽

pp. no-no

Author(s):

Hai-Feng Cui ◽

Peng Li ◽

Xiao-Wei Wang ◽

Zhuo Chai ◽

Ying-Quan Yang ◽

...

Keyword(s):

Michael Addition ◽

Enantioselective Synthesis ◽

Asymmetric Michael Addition ◽

Nitro Esters

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ChemInform Abstract: An Asymmetric Michael Addition of α,α-Disubstituted Aldehydes to Maleimides Leading to a One-Pot Enantioselective Synthesis of Lactones Catalyzed by Amino Acids.

ChemInform ◽

10.1002/chin.201337096 ◽

2013 ◽

Vol 44 (37) ◽

pp. no-no

Author(s):

Christoforos G. Kokotos

Keyword(s):

Amino Acids ◽

Michael Addition ◽

Enantioselective Synthesis ◽

One Pot ◽

Asymmetric Michael Addition

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Cover Feature: α‐Amino Acids and α,β‐Dipeptides Intercalated into Hydrotalcite: Efficient Catalysts in the Asymmetric Michael Addition Reaction of Aldehydes to N ‐Substituted Maleimides (Eur. J. Org. Chem. 37/2021)

European Journal of Organic Chemistry ◽

10.1002/ejoc.202101146 ◽

2021 ◽

Vol 2021 (37) ◽

pp. 5105-5105

Author(s):

José M. Landeros ◽

Carlos Cruz‐Hernández ◽

Eusebio Juaristi

Keyword(s):

Amino Acids ◽

Michael Addition ◽

Addition Reaction ◽

Michael Addition Reaction ◽

Asymmetric Michael Addition

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Surface-Improved Asymmetric Michael Addition Catalyzed by Amino Acids Adsorbed on Laponite

Advanced Synthesis & Catalysis ◽

10.1002/adsc.201701627 ◽

2018 ◽

Vol 360 (10) ◽

pp. 1992-2004 ◽

Cited By ~ 11

Author(s):

György Szőllősi ◽

Dániel Gombkötő ◽

Attila Zsolt Mogyorós ◽

Ferenc Fülöp

Keyword(s):

Amino Acids ◽

Michael Addition ◽

Asymmetric Michael Addition

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ChemInform Abstract: Organocatalytic Asymmetric Michael Addition of Ethyl Nitroacetate to Enones Using Natural Amino Acids-Derived C1-Symmetric Chiral Primary-Secondary Diamines.

ChemInform ◽

10.1002/chin.201337060 ◽

2013 ◽

Vol 44 (37) ◽

pp. no-no

Author(s):

Yirong Zhou ◽

Qiang Liu ◽

Yuefa Gong

Keyword(s):

Amino Acids ◽

Michael Addition ◽

Asymmetric Michael Addition ◽

Ethyl Nitroacetate ◽

Natural Amino Acids

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Organocatalytic asymmetric Michael addition of ethyl nitroacetate to enones using natural amino acids-derived C1-symmetric chiral primary–secondary diamines

Tetrahedron Letters ◽

10.1016/j.tetlet.2013.04.005 ◽

2013 ◽

Vol 54 (23) ◽

pp. 3011-3014 ◽

Cited By ~ 12

Author(s):

Yirong Zhou ◽

Qiang Liu ◽

Yuefa Gong

Keyword(s):

Amino Acids ◽

Michael Addition ◽

Asymmetric Michael Addition ◽

Ethyl Nitroacetate ◽

Natural Amino Acids

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An Asymmetric Michael Addition of α,α-Disubstituted Aldehydes to Maleimides Leading to a One-Pot Enantioselective Synthesis of Lactones Catalyzed by Amino Acids

Organic Letters ◽

10.1021/ol4008662 ◽

2013 ◽

Vol 15 (10) ◽

pp. 2406-2409 ◽

Cited By ~ 61

Author(s):

Christoforos G. Kokotos

Keyword(s):

Amino Acids ◽

Michael Addition ◽

Enantioselective Synthesis ◽

One Pot ◽

Asymmetric Michael Addition

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α‐Amino Acids and α,β‐Dipeptides Intercalated into Hydrotalcite: Efficient Catalysts in the Asymmetric Michael Addition Reaction of Aldehydes to N ‐Substituted Maleimides

European Journal of Organic Chemistry ◽

10.1002/ejoc.202100877 ◽

2021 ◽

Vol 2021 (37) ◽

pp. 5117-5126

Author(s):

José M. Landeros ◽

Carlos Cruz‐Hernández ◽

Eusebio Juaristi

Keyword(s):

Amino Acids ◽

Michael Addition ◽

Addition Reaction ◽

Michael Addition Reaction ◽

Asymmetric Michael Addition

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Highly enantioselective synthesis of α-fluoro-α-nitro esters via organocatalyzed asymmetric Michael addition

Tetrahedron ◽

10.1016/j.tet.2010.11.041 ◽

2011 ◽

Vol 67 (2) ◽

pp. 312-317 ◽

Cited By ~ 30

Author(s):

Hai-Feng Cui ◽

Peng Li ◽

Xiao-Wei Wang ◽

Zhuo Chai ◽

Ying-Quan Yang ◽

...

Keyword(s):

Michael Addition ◽

Enantioselective Synthesis ◽

Asymmetric Michael Addition ◽

Nitro Esters

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