Accelerated Fmoc solid-phase synthesis of peptides with aggregation-disrupting backbones

Yi-Chao Huang; Chao-Jian Guan; Xiang-Long Tan; Chen-Chen Chen; Qing-Xiang Guo; Yi-Ming Li

doi:10.1039/c4ob02260b

Accelerated Fmoc solid-phase synthesis of peptides with aggregation-disrupting backbones

Organic & Biomolecular Chemistry ◽

10.1039/c4ob02260b ◽

2015 ◽

Vol 13 (5) ◽

pp. 1500-1506 ◽

Cited By ~ 17

Author(s):

Yi-Chao Huang ◽

Chao-Jian Guan ◽

Xiang-Long Tan ◽

Chen-Chen Chen ◽

Qing-Xiang Guo ◽

...

Keyword(s):

Solid Phase Synthesis ◽

Solid Phase ◽

Phase Synthesis ◽

Fmoc Solid Phase Synthesis

In this work, we describe an accelerated solid-phase synthetic protocol for ordinary or difficult peptides involving air-bath heating and amide protection.

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Faculty Opinions recommendation of Alternative to piperidine in Fmoc solid-phase synthesis.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1031820.367940 ◽

2006 ◽

Author(s):

Anthony Czarnik

Keyword(s):

Solid Phase Synthesis ◽

Solid Phase ◽

Phase Synthesis ◽

Fmoc Solid Phase Synthesis

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Improved Fmoc-Solid Phase Synthesis of β-Amyloid Peptides Using DBU as Nα-Deprotection Reagent

Peptides: The Wave of the Future ◽

10.1007/978-94-010-0464-0_109 ◽

2001 ◽

pp. 242-243

Author(s):

Anna K. Tickler ◽

Colin J. Barrow ◽

John D. Wade

Keyword(s):

Solid Phase Synthesis ◽

Solid Phase ◽

Phase Synthesis ◽

Amyloid Peptides ◽

Β Amyloid ◽

Fmoc Solid Phase Synthesis

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SAL: A silicon-based linkage agent for fmoc solid phase synthesis: Improved yields of peptide amides containing tryptophan

Peptides ◽

10.1007/978-94-011-0683-2_41 ◽

1994 ◽

pp. 138-140

Author(s):

H.-G. Chao ◽

M.S. Bernatowicz ◽

G.R. Matsueda

Keyword(s):

Solid Phase Synthesis ◽

Solid Phase ◽

Phase Synthesis ◽

Fmoc Solid Phase Synthesis ◽

Silicon Based

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Alternative strategies for the Fmoc solid phase synthesis of phosphotyrosine-containing peptides

Peptides ◽

10.1007/978-94-011-2264-1_232 ◽

1992 ◽

pp. 591-592

Author(s):

Eric A. Kitas ◽

Reinhard Knorr ◽

Willi Bannwarth

Keyword(s):

Solid Phase Synthesis ◽

Solid Phase ◽

Alternative Strategies ◽

Phase Synthesis ◽

Fmoc Solid Phase Synthesis

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Efficient Manual Fmoc Solid-Phase Synthesis of the N-Terminal Segment of Surfactant Protein B (SP-B1-25)

Protein and Peptide Letters ◽

10.2174/092986609788681706 ◽

2009 ◽

Vol 16 (7) ◽

pp. 810-814 ◽

Cited By ~ 3

Author(s):

Suria Ramli ◽

Ian Gentle ◽

Benjamin Ross

Keyword(s):

Solid Phase Synthesis ◽

Solid Phase ◽

Surfactant Protein ◽

Terminal Segment ◽

Phase Synthesis ◽

Surfactant Protein B ◽

Fmoc Solid Phase Synthesis ◽

Protein B

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Backbone Amide Linker (BAL) Strategy forNα-9-Fluorenylmethoxycarbonyl (Fmoc) Solid-Phase Synthesis of Unprotected Peptidep-Nitroanilides and Thioesters1

The Journal of Organic Chemistry ◽

10.1021/jo990629o ◽

1999 ◽

Vol 64 (24) ◽

pp. 8761-8769 ◽

Cited By ~ 108

Author(s):

Jordi Alsina ◽

T. Scott Yokum ◽

Fernando Albericio ◽

George Barany

Keyword(s):

Solid Phase Synthesis ◽

Solid Phase ◽

Phase Synthesis ◽

Backbone Amide ◽

Fmoc Solid Phase Synthesis ◽

Backbone Amide Linker

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Fmoc solid phase synthesis of serine phosphopeptides via selective protection of serine and on resin phosphorylation

Tetrahedron Letters ◽

10.1016/s0040-4039(00)75985-5 ◽

1994 ◽

Vol 35 (6) ◽

pp. 869-872 ◽

Cited By ~ 16

Author(s):

Gideon Shapiro ◽

Robert Swoboda ◽

Urs Stauss

Keyword(s):

Solid Phase Synthesis ◽

Solid Phase ◽

Phase Synthesis ◽

Selective Protection ◽

Fmoc Solid Phase Synthesis

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Fmoc Solid-Phase Synthesis of C-Terminal Peptide Thioesters by Formation of a Backbone Pyroglutamyl Imide Moiety

Angewandte Chemie International Edition ◽

10.1002/anie.200903710 ◽

2009 ◽

Vol 48 (40) ◽

pp. 7411-7414 ◽

Cited By ~ 64

Author(s):

A. Pernille Tofteng ◽

Kasper K. Sørensen ◽

Kilian W. Conde-Frieboes ◽

Thomas Hoeg-Jensen ◽

Knud J. Jensen

Keyword(s):

Solid Phase Synthesis ◽

Solid Phase ◽

Phase Synthesis ◽

Fmoc Solid Phase Synthesis ◽

Peptide Thioesters

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Novel prodrug approach to photodynamic therapy: Fmoc solid-phase synthesis of a cell permeable peptide incorporating 5-aminolaevulinic acid

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2007.05.095 ◽

2007 ◽

Vol 17 (16) ◽

pp. 4518-4522 ◽

Cited By ~ 15

Author(s):

Mark J. Dixon ◽

Ludovic Bourré ◽

Alexander J. MacRobert ◽

Ian M. Eggleston

Keyword(s):

Photodynamic Therapy ◽

Solid Phase Synthesis ◽

Solid Phase ◽

Phase Synthesis ◽

Aminolaevulinic Acid ◽

Cell Permeable Peptide ◽

A Cell ◽

Fmoc Solid Phase Synthesis

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Backbone amide linker (BAL) strategy forNα-9-fluorenylmethoxycarbonyl (Fmoc) solid-phase synthesis of peptide aldehydes

Journal of Peptide Science ◽

10.1002/psc.614 ◽

2005 ◽

Vol 11 (9) ◽

pp. 525-535 ◽

Cited By ~ 16

Author(s):

Joseph C. Kappel ◽

George Barany

Keyword(s):

Solid Phase Synthesis ◽

Solid Phase ◽

Phase Synthesis ◽

Backbone Amide ◽

Peptide Aldehydes ◽

Fmoc Solid Phase Synthesis ◽

Backbone Amide Linker

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