Plasmonic nanorod arrays of a two-segment dimer and a coaxial cable with 1 nm gap for large field confinement and enhancement

Nanoscale ◽  
2015 ◽  
Vol 7 (4) ◽  
pp. 1463-1470 ◽  
Author(s):  
Zi-Qiang Cheng ◽  
Fan Nan ◽  
Da-Jie Yang ◽  
Yu-Ting Zhong ◽  
Liang Ma ◽  
...  
Keyword(s):  
High Sensitivity ◽  
Coaxial Cable ◽  
Large Field ◽  
Plasmonic Nanostructures ◽  
Nanorod Arrays ◽  
Electronic Nanodevices

Seeking plasmonic nanostructures with large field confinement and enhancement is significant for photonic and electronic nanodevices with high sensitivity, reproducibility, and tunability.

scholarly journals Monolithic integration of nanorod arrays on microfluidic chips for fast and sensitive one-step immunoassays

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Ye Wang ◽  
Jiongdong Zhao ◽  
Yu Zhu ◽  
Shurong Dong ◽  
Yang Liu ◽  
...  
Keyword(s):  
Troponin I ◽  
Specific Antigen ◽  
Monolithic Integration ◽  
Detection Sensitivity ◽  
Quantitative Detection ◽  
Plasmonic Nanostructures ◽  
Nanorod Arrays ◽  
Microfluidic Chips ◽  
One Step ◽  
Flow Through

AbstractHere, we present integrated nanorod arrays on microfluidic chips for fast and sensitive flow-through immunoassays of physiologically relevant macromolecules. Dense arrays of Au nanorods are easily fabricated through one-step oblique angle deposition, which eliminates the requirement of advanced lithography methods. We report the utility of this plasmonic structure to improve the detection limit of the cardiac troponin I (cTnI) assay by over 6 × 105-fold, reaching down to 33.9 fg mL−1 (~1.4 fM), compared with an identical assay on glass substrates. Through monolithic integration with microfluidic elements, the device enables a flow-through assay for quantitative detection of cTnI in the serum with a detection sensitivity of 6.9 pg mL−1 (~0.3 pM) in <6 min, which was 4000 times lower than conventional glass devices. This ultrasensitive detection arises from the large surface area for antibody conjugation and metal-enhanced fluorescent signals through plasmonic nanostructures. Moreover, due to the parallel arrangement of flow paths, simultaneous detection of multiple cancer biomarkers, including prostate-specific antigen and carcinoembryonic antigen, has been fulfilled with increased signal-to-background ratios. Given the high performance of this assay, together with its simple fabrication process that is compatible with standard mass manufacturing techniques, we expect that the prepared integrated nanorod device can bring on-site point-of-care diagnosis closer to reality.

STEM multiplication nano-moiré method with large field of view and high sensitivity

2021 ◽  
Author(s):  
Yao Zhao ◽  
Dongliang Wu ◽  
Jiangfan Zhou ◽  
Huihui Wen ◽  
Zhanwei Liu ◽  
...  
Keyword(s):  
High Sensitivity ◽  
Field Of View ◽  
Large Field ◽  
Moire Method

scholarly journals Observational constraints on the optical and near-infrared emission from the neutron star–black hole binary merger candidate S190814bv

2020 ◽  
Vol 643 ◽  
pp. A113 ◽  
Author(s):  
K. Ackley ◽  
L. Amati ◽  
C. Barbieri ◽  
F. E. Bauer ◽  
S. Benetti ◽  
...  
Keyword(s):  
Black Hole ◽  
Neutron Star ◽  
Gravitational Wave ◽  
Near Infrared ◽  
Large Fraction ◽  
High Sensitivity ◽  
Infrared Emission ◽  
Large Field ◽  
Wide Field ◽  
Targeted Observations

Context. Gravitational wave (GW) astronomy has rapidly reached maturity, becoming a fundamental observing window for modern astrophysics. The coalescences of a few tens of black hole (BH) binaries have been detected, while the number of events possibly including a neutron star (NS) is still limited to a few. On 2019 August 14, the LIGO and Virgo interferometers detected a high-significance event labelled S190814bv. A preliminary analysis of the GW data suggests that the event was likely due to the merger of a compact binary system formed by a BH and a NS. Aims. In this paper, we present our extensive search campaign aimed at uncovering the potential optical and near infrared electromagnetic counterpart of S190814bv. We found no convincing electromagnetic counterpart in our data. We therefore use our non-detection to place limits on the properties of the putative outflows that could have been produced by the binary during and after the merger. Methods. Thanks to the three-detector observation of S190814bv, and given the characteristics of the signal, the LIGO and Virgo Collaborations delivered a relatively narrow localisation in low latency – a 50% (90%) credible area of 5 deg2 (23 deg2) – despite the relatively large distance of 267 ± 52 Mpc. ElectromagNetic counterparts of GRAvitational wave sources at the VEry Large Telescope collaboration members carried out an intensive multi-epoch, multi-instrument observational campaign to identify the possible optical and near infrared counterpart of the event. In addition, the ATLAS, GOTO, GRAWITA-VST, Pan-STARRS, and VINROUGE projects also carried out a search on this event. In this paper, we describe the combined observational campaign of these groups. Results. Our observations allow us to place limits on the presence of any counterpart and discuss the implications for the kilonova (KN), which was possibly generated by this NS–BH merger, and for the strategy of future searches. The typical depth of our wide-field observations, which cover most of the projected sky localisation probability (up to 99.8%, depending on the night and filter considered), is r ∼ 22 (resp. K ∼ 21) in the optical (resp. near infrared). We reach deeper limits in a subset of our galaxy-targeted observations, which cover a total ∼50% of the galaxy-mass-weighted localisation probability. Altogether, our observations allow us to exclude a KN with large ejecta mass M ≳ 0.1 M⊙ to a high (> 90%) confidence, and we can exclude much smaller masses in a sub-sample of our observations. This disfavours the tidal disruption of the neutron star during the merger. Conclusions. Despite the sensitive instruments involved in the campaign, given the distance of S190814bv, we could not reach sufficiently deep limits to constrain a KN comparable in luminosity to AT 2017gfo on a large fraction of the localisation probability. This suggests that future (likely common) events at a few hundred megaparsecs will be detected only by large facilities with both a high sensitivity and large field of view. Galaxy-targeted observations can reach the needed depth over a relevant portion of the localisation probability with a smaller investment of resources, but the number of galaxies to be targeted in order to get a fairly complete coverage is large, even in the case of a localisation as good as that of this event.

scholarly journals Miniscope-LFOV: A large field of view, single cell resolution, miniature microscope for wired and wire-free imaging of neural dynamics in freely behaving animals

2021 ◽  
Author(s):  
Changliang Guo ◽  
Garrett J. Blair ◽  
Megha Sehgal ◽  
Federico N. Sangiuliano Jimka ◽  
Arash Bellafard ◽  
...  
Keyword(s):  
Single Cell ◽  
Open Source ◽  
Coaxial Cable ◽  
Field Of View ◽  
Large Field ◽  
Head Orientation ◽  
Cranial Window ◽  
Multiple Imaging ◽  
Free Data ◽  
Freely Behaving

We present a large field of view (FOV) open-source miniature microscope (MiniLFOV) designed to extend the capabilities of the UCLA Miniscope platform to large-scale, single cell resolution neural imaging in freely behaving large rodents and head-fixed mice. This system is capable of multiple imaging configurations, including deep brain imaging using implanted optical probes and cortical imaging through cranial windows. The MiniLFOV interfaces with existing open-source UCLA Miniscope DAQ hardware and software, can achieve single cell resolution imaging across a 3.6 × 2.7 mm field of view at 23 frames per second, has an electrically adjustable working distance of up to 3.5 mm±150 µm using an onboard electrowetting lens, incorporates an absolute head-orientation sensor, and weighs under 14 grams. The MiniLFOV provides a 30-fold larger FOV and yields 20-fold better sensitivity than Miniscope V3, and a 12-fold larger FOV with 2-fold better sensitivity than Miniscope V4. Power and data transmission are handled through a single, flexible coaxial cable down to 0.3 mm in diameter facilitating naturalistic behavior. We validated the MiniLFOV in freely behaving rats by simultaneously imaging >1000 GCaMP7s expressing neurons in the CA1 layer of the hippocampus and in head-fixed mice by simultaneously imaging ~2000 neurons in the mouse dorsal cortex through a 4 × 4 mm cranial window. For freely behaving experiments, the MiniLFOV supports optional wire-free operation using a 3.5 g wire-free data acquisition expansion board which enables close to 1-hour of wire-free recording with a 400 mAh (7.5 g) on-board single-cell lithium-polymer battery and expands wire-free imaging techniques to larger animal models. We expect this new open-source implementation of the UCLA Miniscope platform will enable researchers to address novel hypotheses concerning brain function in freely behaving animals.

WO3-x Nanorod Arrays Based Sensors with High Sensitivity and Quick Response for Detecting Pollutants

2008 ◽  
Vol 1080 ◽  
Author(s):  
Xinpeng Wang ◽  
Jie Lou ◽  
Zhenbo Wang ◽  
Peter Xianping Feng
Keyword(s):  
Experimental Data ◽  
Recovery Time ◽  
Room Temperature ◽  
Operating Temperature ◽  
High Sensitivity ◽  
Two Dimensional ◽  
Quick Response ◽  
Nanorod Arrays ◽  
Highly Sensitive ◽  
Different Temperatures

ABSTRACTTungsten oxide nanorod arrays deposited on the cylindrical substrate have been used for fabrication of a two-dimensional (2D) sensor. The sensibility and capacity towards methane and acetone at different temperatures have been examined. Experimental data have indicated that the newly designed sensor is highly sensitive to methane with low cross sensitivity towards possible mixed organic gas acetone, relying on the operating temperature. At room temperature (20°C), a quick response time and recovery time of the sensor, less than 10 ms, have been obtained.

scholarly journals Following up the afterglow: strategy for X-ray observation triggered by gravitational wave events

2022 ◽  
Vol 21 (12) ◽  
pp. 308
Author(s):  
Mu-Xin Liu ◽  
Hui Tong ◽  
Yi-Ming Hu ◽  
Man-Leong Chan ◽  
Zhu Liu ◽  
...  
Keyword(s):  
Gravitational Wave ◽  
Binary Systems ◽  
Early Stage ◽  
High Sensitivity ◽  
Field Of View ◽  
Large Field ◽  
Wide Field ◽  
X Ray ◽  
Binary Neutron Star ◽  
Wave Event

Abstract The multi-messenger observation of coalescing compact binary systems promises great scientific treasure. However, synthesising observations from both gravitational wave and electromagnetic channels remains challenging. In the context of the day-to-week long emission from a macronova, the binary neutron star merger GW170817 remains the only event with successful electromagnetic followup. In this manuscript, we explore the possibility of using the early stage X-ray afterglow to search for the electromagnetic counterpart of a gravitational wave event. Two algorithms, the simple and straightforward sequential observation (SO) and the step-wise optimizing local optimization are considered and applied to some simulated events. We consider the WXT from the proposed Einstein Probe as a candidate X-ray telescope, which has a very wide field of view of 3600 deg2. Benefiting from the large field of view and high sensitivity, we find that the SO algorithm not only is easy to implement, but also promises a good chance of actual detection.

scholarly journals DOAS measurements of NO<sub>2</sub> from an ultralight aircraft during the Earth Challenge expedition

2012 ◽  
Vol 5 (8) ◽  
pp. 2057-2068 ◽  
Author(s):  
A. Merlaud ◽  
M. Van Roozendael ◽  
J. van Gent ◽  
C. Fayt ◽  
J. Maes ◽  
...  
Keyword(s):  
High Sensitivity ◽  
Large Field ◽  
Optical Absorption Spectroscopy ◽  
Data Sets ◽  
Ozone Monitoring Instrument ◽  
Satellite Measurements ◽  
Po Valley ◽  
The Earth ◽  
Ozone Monitoring ◽  
Set Up

Abstract. We report on airborne Differential Optical Absorption Spectroscopy (DOAS) measurements of NO2 tropospheric columns above South Asia, the Arabic peninsula, North Africa, and Italy in November and December 2009. The DOAS instrument was installed on an ultralight aircraft involved in the Earth Challenge project, an expedition of seven pilots flying on four ultralight aircraft between Australia and Belgium. The instrument recorded spectra in limb geometry with a large field of view, a set-up which provides a high sensitivity to the boundary layer NO2 while minimizing the uncertainties related to the attitude variations. We compare our measurements with OMI (Ozone Monitoring Instrument) and GOME-2 (Global Ozone Monitoring Experiment 2) tropospheric NO2 products when the latter are available. Above Rajasthan and the Po Valley, two areas where the NO2 field is homogeneous, data sets agree very well. Our measurements in these areas are 0.1 ± 0.1 to 3 ± 1 × 1015 molec cm−2 and 2.6 ± 0.8 × 1016 molec cm−2, respectively. Flying downwind of Riyadh, our NO2 measurements show the structure of the megacity's exhaust plume with a higher spatial resolution than OMI. Moreover, our measurements are larger (up to 40%) than those seen by satellites. We also derived tropospheric columns when no satellite data were available if it was possible to get information on the visibility from satellite measurements of aerosol optical thickness. This experiment also provides a confirmation for the recent finding of a soil signature above desert.

Highly sensitive detection of nitrite by using gold nanoparticle-decorated α-Fe2O3 nanorod arrays as self-supporting photo-electrodes

2019 ◽  
Vol 6 (6) ◽  
pp. 1432-1441 ◽  
Author(s):  
Shenghong Kang ◽  
Haimin Zhang ◽  
Guozhong Wang ◽  
Yunxia Zhang ◽  
Huijun Zhao ◽  
...  
Keyword(s):  
Gold Nanoparticle ◽  
Limit Of Detection ◽  
High Sensitivity ◽  
Sensitive Detection ◽  
Nanorod Arrays ◽  
Highly Sensitive ◽  
Highly Sensitive Detection

Gold nanoparticle (Au NP)-decorated-Fe2O3 nanorod arrays (AuNPs-Fe2O3) as a photoelectrode are applied to the detection of nitrite solution with a low limit of detection and high sensitivity.

scholarly journals High resolution and sensitivity gamma camera with active septa. A first Monte Carlo study

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Victor Ilisie ◽  
Laura Moliner ◽  
Sandra Oliver ◽  
Filomeno Sánchez ◽  
Antonio J. González ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Gamma Camera ◽  
Single Photon ◽  
Photon Emission ◽  
High Sensitivity ◽  
Large Field ◽  
Emission Computed Tomography ◽  
Nuclear Medicine Imaging ◽  
Pinhole Collimator ◽  
The Impact

AbstractGamma cameras are of great interest due to their high potential in the field of Nuclear Medicine Imaging. They allow for an early diagnosis of reduced size tumors, and also for a wide variety of preclinical studies with the aim of designing more effective treatments against cancer. In this work we propose a significantly improved multi-pinhole collimator gamma camera and perform a first Monte Carlo analysis of its characteristics. Maintaining the configuration of a multi-pinhole collimator with a high degree of overlapping (thus with a high sensitivity), we add a new element, an active septa, that besides acting as a collimator, is able to measure the impact coordinates of the incident photon. This way one is able to unambiguously identify through which pinhole any gamma ray passes before being detected. The result is a high sensitivity and resolution multi-pinhole gamma camera with an arbitrarily large field of view. As a consequence, the final reconstructed image does not suffer from the undesired artifacts or truncation associated to the multiplexing phenomenon. In this study we focus on the development of a system able to visualize in 3D tumors, nodes and metastasis in real time in the operating room with very low dose. We also briefly analyse and propose a novel design for a Single Photon Emission Computed Tomography system.

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