Smart pH- and reduction-dual-responsive folate–PEG-coated polymeric lipid vesicles for tumor-triggered targeted drug delivery

Nanoscale ◽  
2014 ◽  
Vol 6 (13) ◽  
pp. 7635 ◽  
Author(s):  
Sheng Wang ◽  
Hanjie Wang ◽  
Zhongyun Liu ◽  
Liangliang Wang ◽  
Xiaomin Wang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Targeted Drug Delivery ◽  
Lipid Vesicles ◽  
Dual Responsive ◽  
Targeted Drug

Dual responsive PNIPAM–chitosan targeted magnetic nanopolymers for targeted drug delivery

2015 ◽  
Vol 380 ◽  
pp. 315-320 ◽  
Author(s):  
Tejabhiram Yadavalli ◽  
Shivaraman Ramasamy ◽  
Gopalakrishnan Chandrasekaran ◽  
Isaac Michael ◽  
Helen Annal Therese ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Targeted Drug Delivery ◽  
Dual Responsive ◽  
Targeted Drug

Investigation of Nano Lipid Vesicles of Lornoxicam for Targeted Drug Delivery

2016 ◽  
Vol 11 (6) ◽  
pp. 1-15
Author(s):  
Akhilesh Dubey ◽  
Prabhakara Prabhu ◽  
Jasmine Patel ◽  
Srinivas Hebbar ◽  
C Shastry ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Targeted Drug Delivery ◽  
Lipid Vesicles ◽  
Targeted Drug

scholarly journals Photo and Redox Dual Responsive Reversibly Cross-Linked Nanocarrier for Efficient Tumor-Targeted Drug Delivery

2014 ◽  
Vol 6 (13) ◽  
pp. 10381-10392 ◽  
Author(s):  
Yu Shao ◽  
Changying Shi ◽  
Gaofei Xu ◽  
DanDan Guo ◽  
Juntao Luo
Keyword(s):  
Drug Delivery ◽  
Targeted Drug Delivery ◽  
Dual Responsive ◽  
Targeted Drug

pH and Redox Dual Responsive Nanoparticle for Nuclear Targeted Drug Delivery

2012 ◽  
Vol 9 (9) ◽  
pp. 2719-2729 ◽  
Author(s):  
Remant Bahadur K. C. ◽  
Bindu Thapa ◽  
Peisheng Xu
Keyword(s):  
Drug Delivery ◽  
Targeted Drug Delivery ◽  
Dual Responsive ◽  
Targeted Drug

TEMPERATURE AND PH RESPONSIVE POLYMERIC NANOPARTICLES FOR TARGETED OXALIPLATIN DELIVERY

INDIAN DRUGS ◽  
2018 ◽  
Vol 55 (11) ◽  
pp. 74-77
Author(s):  
A. S Patil ◽  
◽  
A. P. Gadad
Keyword(s):  
Drug Delivery ◽  
Side Effects ◽  
Targeted Drug Delivery ◽  
Polymeric Nanoparticles ◽  
Ph Responsive ◽  
In Vitro Drug Release ◽  
Dual Responsive ◽  
Targeted Drug ◽  
Targeted Drug Delivery System

In the present study temperature and pH responsive co-polymer chitosan-g-poly(N-isopropylacrylamide) (CS-g-PNIPAAm) was synthesized, characterized and efficiently loaded with oxaliplatin. Nanoparticles were evaluated for their physicochemical properties. The drug loaded nanoparticles showed smooth and spherical morphology with loading efficiency and drug content of about 80.7% and 48.7%, respectively. The in vitro drug release was significantly higher at tumor extracellular pH and temperature when compared to physiological pH and temperature. In conclusion, the developed nanoparticulate system is an effective dual responsive targeted drug delivery system for oxaliplatin with low toxic side effects.

Folate-decorated redox/pH dual-responsive degradable prodrug micelles for tumor triggered targeted drug delivery

RSC Advances ◽  
2016 ◽  
Vol 6 (67) ◽  
pp. 62630-62639 ◽  
Author(s):  
Seyed Jamal Tabatabaei Rezaei ◽  
Laila Sarbaz ◽  
Hassan Niknejad
Keyword(s):  
Drug Delivery ◽  
Targeted Drug Delivery ◽  
Intracellular Delivery ◽  
Dual Responsive ◽  
Polymeric Prodrug ◽  
Intracellular Glutathione ◽  
Targeted Drug ◽  
Ph Level

Multifunctional polymeric prodrug micelles, which allow the targeted intracellular delivery and facilitated release of conjugated drugs at cytoplasm in response to an intracellular glutathione and pH level, were developed.

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