Synthesis, crystal structure and properties of sandwich type compounds based on {AsW9} and a hexa-nuclear unit with three supporting TM–triazole complexes

2015 ◽  
Vol 39 (2) ◽  
pp. 1139-1147 ◽  
Author(s):  
Jia-min Liu ◽  
Lu Wang ◽  
Kai Yu ◽  
Zhan-hua Su ◽  
Chun-xiao Wang ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Hela Cells ◽  
Electrocatalytic Activity ◽  
Inhibitory Effect ◽  
Structure And Properties ◽  
Sandwich Compounds ◽  
Good Electrocatalytic Activity ◽  
Sandwich Type

Tree {AsW9}-based sandwich compounds exhibit good electrocatalytic activity, antiferromagnetic interactions, and inhibitory effect on proliferation of HeLa cells.

Synthesis, crystal structure, and properties of two sandwich-type tungstovanadates

2009 ◽  
Vol 362 (8) ◽  
pp. 2796-2801 ◽  
Author(s):  
Bao Li ◽  
Yi Yan ◽  
Fengyan Li ◽  
Lin Xu ◽  
Lihua Bi ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Structure And Properties ◽  
Sandwich Type

Synthesis, crystal structure and properties of a 2D hexa-nuclear ring Cu/Na-substituted sandwich-type arsenotungstate

2019 ◽  
Vol 103 ◽  
pp. 136-141
Author(s):  
Xiujuan Ma ◽  
Zhanhua Su ◽  
Zhifeng Zhao ◽  
Baibin Zhou ◽  
Kai Yu ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Structure And Properties ◽  
Nuclear Ring ◽  
Sandwich Type

CRYSTAL STRUCTURE AND PROPERTIES OF NEW CADMIUMAND THALLIUM-CONTAINING PEROVSKITES

1972 ◽  
Vol 33 (C2) ◽  
pp. C2-241-C2-242
Author(s):  
Yu. N. VENEVTSEV ◽  
A. G. KAPYSHEV ◽  
V. M. LEBEDEV ◽  
V. D. SAL'NIKOV ◽  
G. S. ZHDANOV
Keyword(s):  
Crystal Structure ◽  
Structure And Properties

scholarly journals Apoptotic effect of novel pyrazolone-based derivative [Cu(PMPP-SAL)(EtOH)] on HeLa cells and its mechanism

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Delizhaer Reheman ◽  
Jing Zhao ◽  
Shan Guan ◽  
Guan-Cheng Xu ◽  
Yi-Jie Li ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Cervical Cancer ◽  
Hela Cells ◽  
Copper Complexes ◽  
Antibacterial Properties ◽  
Inhibitory Effect ◽  
Parp Cleavage ◽  
Potential Candidate ◽  
Tnf Α

Abstract Pyrazolone complexes have strong anti-tumor and antibacterial properties, but the anti-tumor mechanism of pyrazolone-based copper complexes has not been fully understood. In this study, the possible mechanism and the inhibitory effect of a novel pyrazolone-based derivative compound [Cu(PMPP-SAL)(EtOH)] on human cervical cancer cells (HeLa cells) was investigated. [Cu(PMPP-SAL)(EtOH)] effectively inhibited proliferation of HeLa cells in vitro with an IC50 value of 2.082 after treatment for 72 h. Cell cycle analysis showed apoptosis was induced by blocking the cell cycle in the S phase. [Cu(PMPP-SAL)(EtOH)] promoted the loss of mitochondrial membrane potential, release of cytochrome c, PARP cleavage, and activation of caspase-3/9 in HeLa cells. Additionally, [Cu(PMPP-SAL)(EtOH)] inhibited the PI3K/AKT pathway and activated the P38/MAPK, and JNK/MAPK pathways. [Cu(PMPP-SAL)(EtOH)] also inhibited the phosphorylation of Iκ-Bα in the NF-κB pathway activated by TNF-α, thus restricting the proliferation of HeLa cells which were activated by TNF-α. In conclusion, [Cu(PMPP-SAL)(EtOH)] inhibited the growth of HeLa cells and induced apoptosis possibly via the caspase-dependent mitochondria-mediated pathway. These results suggest that [Cu(PMPP-SAL)(EtOH)] can be a potential candidate for the treatment of cervical cancer.

scholarly journals The Inhibitory Effect of a Novel Polypeptide Fraction fromArca subcrenataon Cancer-Related Inflammation in Human Cervical Cancer HeLa Cells

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Yu Wu ◽  
Xianjing Hu ◽  
Liyan Song ◽  
Jianhua Zhu ◽  
Rongmin Yu
Keyword(s):  
Cervical Cancer ◽  
Hela Cells ◽  
Molecular Mechanisms ◽  
Tumor Development ◽  
Basic Research ◽  
Inhibitory Effect ◽  
Fishery Resource ◽  
Proinflammatory Mediators ◽  
Raw264.7 Macrophage ◽  
Human Cervical Cancer

Inflammation is known to be closely associated with the development of cancer. The study was launched in human cervical cancer HeLa cells to investigate the antitumor and anti-inflammatory effects of P2, a marine polypeptide fraction from an important fishery resourceArca subcrenata. The basic research showed that P2 could suppress the production of nitric oxide in LPS-induced RAW264.7 macrophage cells as well as the secretion of inflammatory cytokines IL-6 and TNF-αin human cervical cancer HeLa cells. For the molecular mechanisms, P2 was shown to downregulate the gene expression of proinflammatory cytokines IL-6 and IL-8 and to inhibit the COX-2 and iNOS-related pathways in HeLa cells. In consequence, P2 might inhibit tumor development by blocking the interaction between tumor microenvironment and proinflammatory mediators. All findings indicate that P2 possesses the potential to be developed as a novel agent for cancer therapy.

Crystal structure and properties of the new complex vanadium oxide K2SrV3O9

2005 ◽  
Vol 40 (5) ◽  
pp. 800-809 ◽  
Author(s):  
Alexander A. Tsirlin ◽  
Victoria V. Chernaya ◽  
Roman V. Shpanchenko ◽  
Evgeny V. Antipov ◽  
Joke Hadermann
Keyword(s):  
Crystal Structure ◽  
Vanadium Oxide ◽  
Structure And Properties
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