Engineering interconnected 3D vascular networks in hydrogels using molded sodium alginate lattice as the sacrificial template

Lab on a Chip ◽  
2014 ◽  
Vol 14 (15) ◽  
pp. 2709-2716 ◽  
Author(s):  
Xue-Ying Wang ◽  
Zi-He Jin ◽  
Bo-Wen Gan ◽  
Song-Wei Lv ◽  
Min Xie ◽  
...  

We engineer interconnected 3D vascular networks in hydrogels using molded sodium alginate lattice as sacrificial templates. The size and morphology of simulated vascular networks were well controlled and a fully-developed endothelial layer was formed.

2019 ◽  
Vol 1 (8) ◽  
pp. 3151-3163 ◽  
Author(s):  
Hicham Abou Oualid ◽  
Othmane Amadine ◽  
Younes Essamlali ◽  
Issam Meftah Kadmiri ◽  
Hicham El Arroussi ◽  
...  

In this work, a bifunctional nanohybrid silver/zinc oxide material (Ag/ZnO) has been synthesized by a rapid route using sodium alginate simultaneously as a sacrificial template and silver reducing agent.


2015 ◽  
Vol 3 (4) ◽  
pp. 592-596 ◽  
Author(s):  
Ilida Ortega ◽  
Lindsey Dew ◽  
Adam G. Kelly ◽  
Chuh K. Chong ◽  
Sheila MacNeil ◽  
...  

Electrospinning has been combined with robocasting using alginate as a sacrificial template for the creation of bespoke and perfusable artificial vascular networks.


2019 ◽  
Vol 14 (14) ◽  
pp. 1381-1384
Author(s):  
Jie Chen ◽  
Zhihua Ying ◽  
Peng Zheng ◽  
Rongfa Gao ◽  
Jinbang Mei

2018 ◽  
Vol 15 (3) ◽  
pp. 222-229
Author(s):  
G.G. Belozerskaya ◽  
D.Yu. Bychichko ◽  
V.A. Kabak ◽  
A.R. Lempert ◽  
O.E. Nevedrova ◽  
...  
Keyword(s):  

Author(s):  
Poreddy Srikanth Reddy ◽  
Penjuri Subhash Chandra Bose ◽  
Vuppula Sruthi ◽  
Damineni Saritha

The aim of the present work was to prepare floating tablets of galantamine HBr using sodium alginate and xanthan gum as matrix forming carriers. Galantamine HBr is used for the treatment of mild to moderate Alzheimer's disease and various other memory impairments, in particular those of vascular origin. The matrix tablet formulations were prepared by varying the concentrations of sodium alginate and xanthan gum. The tablets were prepared by direct compression technique using PVP K-30 as a binder and sodium bicarbonate for development of CO2. The prepared matrix tablets were evaluated for properties such as hardness, thickness, friability, weight variation, floating lag time, compatibility using DSC and FTIR. In vitro dissolution was carried out for 12 hrs in 0.1N HCl at 37±0.5 ºC using USP paddle type dissolution apparatus. It was noted that, all the prepared formulations had desired floating lag time and constantly floated on dissolution medium by maintaining the matrix integrity. The drug release from prepared tablets was found to vary with varying concentration of the polymers, sodium alginate and xanthan gum. From the study it was concluded that floating drug delivery system for galantamine HBr can be prepared by using sodium alginate and xanthan gum as a carrier.


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