A mesoporous organosilica grafted Pd catalyst (MOG-Pd) for efficient base free and phosphine free synthesis of tertiary butyl esters via tertiary-butoxycarbonylation of boronic acid derivatives without using carbon monoxide

2015 ◽  
Vol 17 (6) ◽  
pp. 3540-3551 ◽  
Author(s):  
Kajari Ghosh ◽  
Rostam Ali Molla ◽  
Md. Asif Iqubal ◽  
S. M. Islam
Keyword(s):  
Carbon Monoxide ◽  
Boronic Acid ◽  
High Efficiency ◽  
Pd Catalyst ◽  
Tertiary Butyl ◽  
Butyl Esters ◽  
Mesoporous Organosilica ◽  
Green Condition ◽  
Boronic Acid Derivatives

A reusable MOG-Pd catalyst has been synthesized, characterized and it shows high efficiency in tert-butoxycarbonylation under green condition.

ChemInform Abstract: Preparation of tert-Butyl Esters via Pd-Catalyzed tert-Butoxycarbonylation of (Hetero)aryl Boronic Acid Derivatives.

ChemInform ◽  
2014 ◽  
Vol 45 (39) ◽  
pp. no-no
Author(s):  
Xinjian Li ◽  
Dapeng Zou ◽  
Helong Zhu ◽  
Yaping Wang ◽  
Jingya Li ◽  
...  
Keyword(s):  
Boronic Acid ◽  
Tert Butyl ◽  
Butyl Esters ◽  
Boronic Acid Derivatives ◽  
Aryl Boronic Acid

Preparation of tert-Butyl Esters via Pd-Catalyzed tert-Butoxycarbonylation of (Hetero)aryl Boronic Acid Derivatives

2014 ◽  
Vol 16 (7) ◽  
pp. 1836-1839 ◽  
Author(s):  
Xinjian Li ◽  
Dapeng Zou ◽  
Helong Zhu ◽  
Yaping Wang ◽  
Jingya Li ◽  
...  
Keyword(s):  
Boronic Acid ◽  
Tert Butyl ◽  
Butyl Esters ◽  
Boronic Acid Derivatives ◽  
Aryl Boronic Acid

Synthesis of Sugar–Boronic Acid Derivatives: A Class of Potential Agents for Boron Neutron Capture Therapy

2017 ◽  
Vol 19 (7) ◽  
pp. 1678-1681 ◽  
Author(s):  
Daniela Imperio ◽  
Erika Del Grosso ◽  
Silvia Fallarini ◽  
Grazia Lombardi ◽  
Luigi Panza
Keyword(s):  
Boron Neutron Capture Therapy ◽  
Neutron Capture ◽  
Boronic Acid ◽  
Neutron Capture Therapy ◽  
Boron Neutron Capture ◽  
Boronic Acid Derivatives

Recognition and sensing of various species using boronic acid derivatives

2012 ◽  
Vol 48 (48) ◽  
pp. 5956 ◽  
Author(s):  
Zhiqian Guo ◽  
Injae Shin ◽  
Juyoung Yoon
Keyword(s):  
Boronic Acid ◽  
Boronic Acid Derivatives

Titration syntheses of polyaminosubstituted phthalocyanines via nucleophilic aromatic substitutions on zinc(II) 1,2,3,4,8,9,10,11,15,16,17,18,22,23,24,25-hexadecafluorophthalocyanine

2007 ◽  
Vol 11 (07) ◽  
pp. 537-546 ◽  
Author(s):  
Clifford C. Leznoff ◽  
Annette Hiebert ◽  
Sibel Ok
Keyword(s):  
Amino Acids ◽  
Chain Length ◽  
Secondary Amines ◽  
Primary Amines ◽  
Tertiary Butyl ◽  
Butyl Esters ◽  
Mild Conditions ◽  
Nucleophilic Aromatic Substitutions

Primary amines, secondary amines and tertiary butyl esters of amino acids are used as nucleophiles with zinc(II) hexadecafluorophthalocyanine to provide mixtures of mono and disubstituted fluorinated phthalocyanines under mild conditions, or polyaminosubstituted phthalocyanines when using the amines as solvents. Diamines give cyclic substituted phthalocyanines, binuclear or trinuclear phthalocyanines or mixtures of both types, depending on the chain length or structure of the diamine.

The modern role of boron as a 'magic element' in biomedical science: Chemistry perspective

2021 ◽  
Author(s):  
SAURAV CHATTERJEE ◽  
NITESH MANI Mani TRIPATHI ◽  
Anupam Bandyopadhyay
Keyword(s):  
Drug Discovery ◽  
Boronic Acid ◽  
Toxic Element ◽  
Biomedical Science ◽  
Boronic Acid Derivatives

The boron was misconstrued as a toxic element for animals, which retarded the growth of boron-containing drug discovery in the last century. Nevertheless, modern applications of boronic acid derivatives are...

scholarly journals Rapid approach to complex boronic acids

2019 ◽  
Vol 5 (7) ◽  
pp. eaaw4607 ◽  
Author(s):  
Constantinos G. Neochoritis ◽  
Shabnam Shaabani ◽  
Maryam Ahmadianmoghaddam ◽  
Tryfon Zarganes-Tzitzikas ◽  
Li Gao ◽  
...  
Keyword(s):  
Small Molecules ◽  
Boronic Acid ◽  
Multicomponent Reactions ◽  
Chemical Space ◽  
Building Blocks ◽  
Acid Synthesis ◽  
Success Rates ◽  
Boronic Acid Derivatives ◽  
Low Coverage ◽  
Target Synthesis

The compatibility of free boronic acid building blocks in multicomponent reactions to readily create large libraries of diverse and complex small molecules was investigated. Traditionally, boronic acid synthesis is sequential, synthetically demanding, and time-consuming, which leads to high target synthesis times and low coverage of the boronic acid chemical space. We have performed the synthesis of large libraries of boronic acid derivatives based on multiple chemistries and building blocks using acoustic dispensing technology. The synthesis was performed on a nanomole scale with high synthesis success rates. The discovery of a protease inhibitor underscores the usefulness of the approach. Our acoustic dispensing–enabled chemistry paves the way to highly accelerated synthesis and miniaturized reaction scouting, allowing access to unprecedented boronic acid libraries.

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