Regioselective synthesis of functionalized [1,8]naphthyridine derivatives via three-component domino reaction under catalyst-free conditions

2015 ◽  
Vol 17 (2) ◽  
pp. 973-981 ◽  
Author(s):  
Xian Feng ◽  
Jian-Jun Wang ◽  
Juan-Juan Zhang ◽  
Cheng-Pao Cao ◽  
Zhi-Bin Huang ◽  
...  
Keyword(s):  
Reaction Times ◽  
Regioselective Synthesis ◽  
Domino Reaction ◽  
Catalyst Free ◽  
Benign Solvents

The advantages of this protocol are short reaction times, catalyst-free conditions, cheap and benign solvents, and high regio- and stereo-selectivities.

ChemInform Abstract: Regioselective Synthesis of Functionalized [1,8]Naphthyridine Derivatives via Three-Component Domino Reaction under Catalyst-Free Conditions.

ChemInform ◽  
2015 ◽  
Vol 46 (26) ◽  
pp. no-no
Author(s):  
Xian Feng ◽  
Jian-Jun Wang ◽  
Juan-Juan Zhang ◽  
Cheng-Pao Cao ◽  
Zhi-Bin Huang ◽  
...  
Keyword(s):  
Regioselective Synthesis ◽  
Domino Reaction ◽  
Catalyst Free

Acetic acid mediated regioselective synthesis of 2,4,5-trisubstituted thiazoles by a domino multicomponent reaction

2019 ◽  
Vol 43 (22) ◽  
pp. 8644-8650 ◽  
Author(s):  
Mohit Saroha ◽  
Jitender M. Khurana
Keyword(s):  
Acetic Acid ◽  
Multicomponent Reaction ◽  
Regioselective Synthesis ◽  
Domino Reaction ◽  
Thiazole Derivatives ◽  
Active Methylene

Acetic acid mediated regioselective synthesis of novel 2,4,5-trisubstituted thiazole derivatives has been reported by a domino reaction of thiosemicarbazide and aldehydes/ketones/isatin, to generate thiosemicarbazones (in situ) followed by addition of arylglyoxal and active methylene/activated C–H acids/pyrazole/indole in ethanol at 80 °C.

ChemInform Abstract: A Three-Component Domino Reaction of 2-Tetralone, Hydroxylamine and Acetylene: A One-Pot, Highly Regioselective Synthesis of 4,5-Dihydrobenz[e]indoles.

ChemInform ◽  
2010 ◽  
Vol 41 (28) ◽  
pp. no-no
Author(s):  
Alexander M. Vasil'tsov ◽  
Andrei V. Ivanov ◽  
Al'bina I. Mikhaleva ◽  
Boris A. Trofimov
Keyword(s):  
Regioselective Synthesis ◽  
Domino Reaction ◽  
One Pot

ChemInform Abstract: Catalyst-Free Three-Component Domino Reactions for Regioselective Synthesis of Multi-Functional Fused Pyrroles.

ChemInform ◽  
2015 ◽  
Vol 46 (41) ◽  
pp. no-no
Author(s):  
Xue-Bing Chen ◽  
Sheng-Jiao Yan ◽  
An Su ◽  
Wei Liu ◽  
Jun Lin
Keyword(s):  
Regioselective Synthesis ◽  
Domino Reactions ◽  
Catalyst Free

Solvent-promoted catalyst-free regioselective N-incorporation multicomponent domino reaction: rapid assembly of π-functionalized [60]fullerene-fused dihydrocarbolines

2018 ◽  
Vol 54 (95) ◽  
pp. 13331-13334 ◽  
Author(s):  
Tong-Xin Liu ◽  
Shuaishuai Yue ◽  
Changgeng Wei ◽  
Nana Ma ◽  
Pengling Zhang ◽  
...  
Keyword(s):  
Domino Reaction ◽  
Direct Construction ◽  
Catalyst Free ◽  
N Incorporation

An unprecedented solvent-promoted N-incorporation multicomponent domino chemistry was developed for the direct construction of π-functionalized [60]fullerene-fused dihydrocarbolines from simple hydrocarbons.

Catalyst-free three-component domino reactions for regioselective synthesis of multi-functional fused pyrroles

Tetrahedron ◽  
2015 ◽  
Vol 71 (29) ◽  
pp. 4745-4751 ◽  
Author(s):  
Xue-Bing Chen ◽  
Sheng-Jiao Yan ◽  
An Su ◽  
Wei Liu ◽  
Jun Lin
Keyword(s):  
Regioselective Synthesis ◽  
Domino Reactions ◽  
Catalyst Free

Regioselective synthesis of spiro isoxazole‐oxindole‐tetrahydrothiophene hybrids via cascade reactions under catalyst‐free conditions

2019 ◽  
Vol 57 (1) ◽  
pp. 469-476 ◽  
Author(s):  
Sakkani Nagaraju ◽  
Kota Sathish ◽  
Neeli Satyanarayana ◽  
Banoth Paplal ◽  
Dhurke Kashinath
Keyword(s):  
Cascade Reactions ◽  
Regioselective Synthesis ◽  
Catalyst Free

Construction of benzothiophene fused pyrrolidone in water via a catalyst-free process and a mechanism study

2020 ◽  
Vol 22 (20) ◽  
pp. 6798-6803 ◽  
Author(s):  
Jinhui Shen ◽  
Aimin Yu ◽  
Lei Zhang ◽  
Xiangtai Meng
Keyword(s):  
Environmentally Benign ◽  
Domino Reaction ◽  
Mechanism Study ◽  
Catalyst Free ◽  
Free Process

A novel three-component domino reaction towards benzothiophene fused pyrrolidone derivatives was developed in an environmentally benign manner.

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