Gentio-oligosaccharides from Leuconostoc mesenteroides NRRL B-1426 dextransucrase as prebiotics and as a supplement for functional foods with anti-cancer properties

2015 ◽  
Vol 6 (2) ◽  
pp. 604-611 ◽  
Author(s):  
Damini Kothari ◽  
Arun Goyal
Keyword(s):  
Colon Carcinoma ◽  
Functional Foods ◽  
Leuconostoc Mesenteroides ◽  
Human Colon ◽  
Selective Inhibition ◽  
Prebiotic Activity ◽  
Human Colon Carcinoma ◽  
Anti Cancer ◽  
Ht 29

Gentio-oligosaccharides (GnOS) fromLeuconostoc mesenteroidesNRRL B-1426 dextransucrase showed potential prebiotic activity and selective inhibition of human colon carcinoma (HT-29) cells.

Protein kinase C and casein kinase II activities in two human colon carcinoma cell lines, HT-29 and CaCo-2: Possible correlation with differentiation

1990 ◽  
Vol 10 (3) ◽  
pp. 293-299 ◽  
Author(s):  
Ewa Rydell ◽  
Karl-Eric Magnusson ◽  
Anita Sjö ◽  
Krister Axelsson
Keyword(s):  
Protein Kinase C ◽  
Protein Kinase ◽  
Colon Carcinoma ◽  
Carcinoma Cell ◽  
Human Colon ◽  
Human Colon Carcinoma Cell ◽  
Carcinoma Cell Lines ◽  
Kinase C ◽  
Human Colon Carcinoma ◽  
Ht 29

Protein kinase C (PK-C) and casein kinase II (CK-II) activities were studied in two human colon carcinoma cell lines (HT-29 and CaCO-2) undergoing differentiation in vitro resulting, in small-intestine-like cells. CaCo-2 cells, when grown under standard conditions, appear to undergo spontaneous differentiation. In these cells PK-C and CK-II activities were determined on day 5, 10 and 15. No significant differences in activities were seen either in PK-C or CK-II activity. HT-29 cells, when grown in glucose-free medium can be stimulated to undergo differentiation which is completed within 20 days. PK-C and CK-II activities were determined after 5, 10, 15, 20 and 25 days, respectively. PK-C activity rose from 7.9±3.5 pmole32P/mg protein/min at day 5 to 37.5±14.8 pmole32P/mg protein/min at day 20. After 25 days the activity was reduced to 20.0±7.8 pmole32P/mg protein/min. CK-II activity did not change significantly during day 5 to 20, but on day 25 there was a significant decrease in CK-II activity from 94.9±6.4 pmole32P/mg protein/min (day 20) to 62.6±3.9 pmole32P/mg protein/min (day 25) p=0.003. The results in this study indicate a role for PK-C and CK-II in cell growth and differentiation.

Sensitizing human colon carcinoma HT-29 cells to cisplatin by cyclopentenylcytosine, in vitro and in vivo

Life Sciences ◽  
2000 ◽  
Vol 68 (1) ◽  
pp. 1-11 ◽  
Author(s):  
Kamran Gharehbaghi ◽  
Thomas Szekeres ◽  
Joel A. Yalowitz ◽  
Monika Fritzer-Szekeres ◽  
Yves G. Pommier ◽  
...  
Keyword(s):  
Colon Carcinoma ◽  
Human Colon ◽  
Human Colon Carcinoma ◽  
Ht 29

scholarly journals Inhibition of ribonucleotide reductase and growth of human colon carcinoma HT-29 cells and mouse leukemia L1210 cells by N-hydroxy-N′-aminoguanidine derivatives

1990 ◽  
Vol 40 (8) ◽  
pp. 1779-1783 ◽  
Author(s):  
Matsumoto Masahiko ◽  
John G. Fox ◽  
Wang Pou-Hsiung ◽  
Phanesh B. Koneru ◽  
Eric J. Lien ◽  
...  
Keyword(s):  
Colon Carcinoma ◽  
Ribonucleotide Reductase ◽  
Human Colon ◽  
Mouse Leukemia ◽  
L1210 Cells ◽  
Human Colon Carcinoma ◽  
Ht 29

Inhibition of proliferation and induction of apoptosis by γ-tocotrienol in human colon carcinoma HT-29 cells

Nutrition ◽  
2009 ◽  
Vol 25 (5) ◽  
pp. 555-566 ◽  
Author(s):  
Wei-Li Xu ◽  
Jia-Ren Liu ◽  
Hui-Kun Liu ◽  
Gui-Yun Qi ◽  
Xiang-Rong Sun ◽  
...  
Keyword(s):  
Colon Carcinoma ◽  
Human Colon ◽  
Inhibition Of Proliferation ◽  
Human Colon Carcinoma ◽  
Induction Of Apoptosis ◽  
Ht 29
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