The differential localization of a methyl group confers a different anti-breast cancer activity to two triterpenes present in olives

2015 ◽  
Vol 6 (1) ◽  
pp. 248-255 ◽  
Author(s):  
Cristina Sánchez-Quesada ◽  
Alicia López-Biedma ◽  
José J. Gaforio
Keyword(s):  
Breast Cancer ◽  
Olive Oil ◽  
Virgin Olive Oil ◽  
Methyl Group ◽  
Minor Fraction ◽  
Differential Localization ◽  
Cancer Activity

Uvaol (UV) and erythrodiol (ER) are two triterpenic dialcohols present in the minor fraction of virgin olive oil, in leaves and in the skin and drupe of olives.

Virgin olive oil minor components as natural drugs for the treatment of breast cancer: preliminary experiments on squalene

2010 ◽  
Vol 3 (3) ◽  
pp. 221-225 ◽  
Author(s):  
José L. Quiles ◽  
Pedro Sánchez-Rovira ◽  
César L. Ramirez-Tortosa ◽  
Sergio Granados-Principal ◽  
Enrico Bertoli ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Olive Oil ◽  
Virgin Olive Oil ◽  
Minor Components ◽  
Natural Drugs

Virgin olive oil minor components as natural drugs for the treatment of breast cancer: preliminary experiments on squalene

2010 ◽  
Vol 3 (3) ◽  
pp. 221-225 ◽  
Author(s):  
José L. Quiles ◽  
Pedro Sánchez-Rovira ◽  
César L. Ramirez-Tortosa ◽  
Sergio Granados-Principal ◽  
Enrico Bertoli ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Olive Oil ◽  
Virgin Olive Oil ◽  
Minor Components ◽  
Natural Drugs

Comparison of weight loss with a National Cancer Institute diet and a plant-based olive oil diet in overweight women with invasive breast cancer

2007 ◽  
Vol 25 (18_suppl) ◽  
pp. 1532-1532
Author(s):  
M. M. Flynn
Keyword(s):  
Breast Cancer ◽  
Olive Oil ◽  
Invasive Breast Cancer ◽  
National Cancer Institute ◽  
Virgin Olive Oil ◽  
Extra Virgin Olive Oil ◽  
Blood Levels ◽  
Fasting Insulin ◽  
Overweight Women ◽  
Total Fat

1532 Background: The risk of breast cancer increases with increasing body weight, higher blood levels of fasting insulin and triglycerides, and lower HDL-c. Weightloss and diet can affect these variables. While diets lower in fat are routinely recommended for weightloss and cancer prevention, there is no firm evidence that they have an advantage compared to diets higher in dietary fat. Further, lower-fat diets can adversely affect fasting blood levels of insulin, triglycerides and HDL-c. Methods: Overweight women diagnosed with invasive breast cancer after the age of 50 consumed a National Cancer Institute diet (NCI; total fat: ≥15% to <30%) and a plant-based, olive oil diet (PBOO; total fat: ≥35%, primarily from extra virgin olive oil) for 8 weeks each in a crossover trial with random assignment to order. Fasting blood samples at the end of each diet were analyzed for insulin, triglycerides and HDL-c. Results: Results for 14 subjects. Percent weightloss (NCI: 4.2 ± 2.3; PBOO: 6.2 ± 2.1) in this preliminary group exhibited a significant diet-order effect. Ten of the 14 had lower levels of fasting insulin while on the PBOO diet. Conclusions: These initial results suggest that weightloss can be achieved with a plant-based, higher-fat diet emphasizing extra virgin olive oil, and such a diet may have a metabolic advantage compared to the standard, lower-fat diet. [Table: see text] No significant financial relationships to disclose.

Simple quantification of phenolic compounds present in the minor fraction of virgin olive oil by LC–DAD–FLD

Talanta ◽  
2012 ◽  
Vol 101 ◽  
pp. 479-487 ◽  
Author(s):  
M.P. Godoy-Caballero ◽  
M.I. Acedo-Valenzuela ◽  
T. Galeano-Díaz
Keyword(s):  
Phenolic Compounds ◽  
Olive Oil ◽  
Virgin Olive Oil ◽  
Minor Fraction

scholarly journals The Role of Dietary Extra Virgin Olive Oil and Corn Oil on the Alteration of Epigenetic Patterns in the Rat DMBA-Induced Breast Cancer Model

PLoS ONE ◽  
2015 ◽  
Vol 10 (9) ◽  
pp. e0138980 ◽  
Author(s):  
Cristina Rodríguez-Miguel ◽  
Raquel Moral ◽  
Raquel Escrich ◽  
Elena Vela ◽  
Montserrat Solanas ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Olive Oil ◽  
Corn Oil ◽  
Virgin Olive Oil ◽  
Extra Virgin Olive Oil ◽  
Cancer Model ◽  
Breast Cancer Model ◽  
Epigenetic Patterns
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