Comparative study of tissue deposition of omega-3 fatty acids from polar-lipid rich oil of the microalgae Nannochloropsis oculata with krill oil in rats

2015 ◽  
Vol 6 (1) ◽  
pp. 185-191 ◽  
Author(s):  
Michael L. Kagan ◽  
Aharon Levy ◽  
Alicia Leikin-Frenkel

An oil from micro-algae rich in EPA with no DHA and consisting of 15% polar lipids (phospholipids and glycolipids) showed equivalent uptake of EPA into rat plasma and organs as omega-3 krill oil consisting of EPA and DHA and 40% phospholipids.

2014 ◽  
Vol 8 ◽  
pp. CMC.S13571 ◽  
Author(s):  
Daniel E. Hilleman ◽  
Mark A. Malesker

The cardiovascular benefits of marine-derived omega-3 fatty acids are supported by epidemiologic and clinical studies. Both healthy patients and those with confirmed coronary heart disease are advised by the American Heart Association to consume omega-3 fatty acids either through dietary fatty fish or fish oil products. We present two case reports of patients with dyslipidemia who were switched from an omega-3 dietary supplement or a prescription omega-3 drug containing eicosapentaenoic acid (EPA) plus docosahexaenoic acid (DHA) to a new prescription EPA-only drug, icosapent ethyl (IPE). Products containing a combination of EPA and DHA, including dietary supplements and prescription products, are more likely to increase low-density lipoprotein cholesterol (LDL-C) levels compared with pure EPA-only products. The lipid profiles of these two patients were improved with IPE treatment, illustrating the potentially favorable effects of IPE compared with other products containing both EPA and DHA.


2020 ◽  
Vol 12 (2) ◽  
Author(s):  
Louisa M. F. Josephus ◽  
Julius Pontoh ◽  
Lidya I. Momuat

ABSTRAK Telah dilakukan penelitian mengenai kandungan lemak dan komposisi asam-asam lemak pada bagian badan ikan julung-julung. Penentuan kadar lemak pada penelitian ini menggunakan metode ekstraksi pemanasan dengan air (wet rendering). Kadar lemak pada bagian badan ikan julung-julung yaitu 0,02%. Ekstrak lemak ikan yang diperoleh di transesterifikasi basa menggunakan metode derivatisasi kemudian diinjeksikan pada alat kromatografi gas. Hasil penelitian ini menyimpulkan bahwa asam-asam lemak utama yang ada pada bagian badan ikan julung-julung adalah asam palmitat dan DHA. Sedangkan untuk asam-asam lemak omega-3 yang diperoleh yaitu asam eikosatrienoat, EPA dan DHA, dengan total kandungan omega-3 pada bagian badan yaitu 27,0%. ABSTRACT Research has been conducted for the fat content and composition of fatty acids in the part of body of the julung-julung fish. Determination of fat content in this study using the method of water heating extraction (wet rendering). Fat content in the part of body of the julung-julung fish is 0.02%. The extract of fish fat was transesterified bases using the derivatization method and then injected on a gas chromatography device. The results of this study prove that the main fatty acids present in the part of body of the julung-julung fish are palmitic acid and DHA. As for the omega-3 fatty acids obtained, namely eicosatrienoic acid, EPA and DHA, with the total omega-3 content in the part of body is 27.0%. 


KIMIKA ◽  
2016 ◽  
Vol 26 (2) ◽  
pp. 39-50 ◽  
Author(s):  
Dave P. Briones ◽  
Nancy Lazaro-Llanos

Fish and other marine products consumption is the main route of heavy metal exposure to human which poses health risks if taken in high dosage. On the other hand, the nutritional benefits of fish are mainly due to the content of high-quality protein and high content of the two kinds of omega-3 polyunsaturated fatty acids (PUFA): eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). The study aims to assess and compare the benefit-risk ratio for the consumption of commonly-consumed fish and products in Metro Manila. Fish and product samples were analyzed for moisture, crude fat, heavy metals (As, Cd, Pb) and fatty acid profile (saturated, mono- and polyunsaturated) including omega-3 fatty acids EPA and DHA. These findings generally indicate that the consumption of fish and products studied posed no risk to human health. Essential fatty acids EPA and DHA were highest for dried anchovy, Stolephorus indicus (1.5 and 7.3mg/g sample); mussel, Mytilus smaragdinus (1.5 and 1.0mg/g sample); round scad, Decapterus macrosoma (0.9 and 3.4mg/g sample); and skipjack tuna, Auxis thazard (1.1 and 3.9mg/g sample). The hazard quotients of essential fatty acids versus heavy metals were also less than 1 except for Cd in squid (1.8), In the case of dried sardine (19.9), squid (1.8), shrimp (3.4), and skipjack tuna (1.7), these foods should be monitored regularly. In conclusion, the target hazard quotients for most of the fish and products showed values less than 1, which suggest that health risks were insignificant.


Nutrients ◽  
2018 ◽  
Vol 10 (4) ◽  
pp. 416 ◽  
Author(s):  
Zhiying Zhang ◽  
Victor Fulgoni ◽  
Penny Kris-Etherton ◽  
Susan Mitmesser

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