scholarly journals Sortase A catalyzed reaction pathways: a comparative study with six SrtA variants

2014 ◽  
Vol 4 (9) ◽  
pp. 2946-2956 ◽  
Author(s):  
Tobias Heck ◽  
Phu-Huy Pham ◽  
Alpaslan Yerlikaya ◽  
Linda Thöny-Meyer ◽  
Michael Richter
Keyword(s):  
Staphylococcus Aureus ◽  
Comparative Study ◽  
Catalytic Properties ◽  
Reaction Pathways ◽  
Sortase A ◽  
Protein Fusion ◽  
Crosslinking Reactions ◽  
Intermolecular Crosslinking

Different enzyme variants of sortase A fromStaphylococcus aureuswere found to have distinct catalytic properties with regard to site-directed protein fusion and competing intermolecular crosslinking reactions.

scholarly journals Infective endocarditis caused by HACEK group bacteria—a registry-based comparative study

2021 ◽  
Author(s):  
Anna Bläckberg ◽  
Christian Morenius ◽  
Lars Olaison ◽  
Andreas Berge ◽  
Magnus Rasmussen
Keyword(s):  
Staphylococcus Aureus ◽  
Infective Endocarditis ◽  
Mortality Rate ◽  
Haemophilus Influenzae ◽  
Comparative Study ◽  
Clinical Characteristics ◽  
Prosthetic Valve ◽  
Prosthetic Valve Endocarditis ◽  
Common Cause ◽  
Prosthetic Valves

AbstractInfective endocarditis (IE) caused by bacteria within Haemophilus (excluding Haemophilus influenzae), Aggregatibacter, Cardiobacterium, Eikenella and Kingella (HACEK) is rare. This study aimed to describe clinical features of IE caused by HACEK genera in comparison with IE due to other pathogens. Cases of IE due to HACEK were identified through the Swedish Registry of Infective Endocarditis (SRIE). Clinical characteristics of IE cases caused by HACEK were compared with cases of IE due to other pathogens reported to the same registry. Ninety-six patients with IE caused by HACEK were identified, and this corresponds to 1.8% of all IE cases. Eighty-three cases were definite endocarditis, and the mortality rate was 2%. The median age was 63 years, which was lower compared to patients with IE caused by other pathogens (66, 70 and 73 years respectively, p ≤ 0.01). Patients with IE caused by Haemophilus were younger compared to patients with IE due to Aggregatibacter (47 vs 67 years, p ≤ 0.001). Patients with IE due to HACEK exhibited longer duration from onset of symptoms to hospitalization and had more prosthetic valve endocarditis compared to patients with IE due to Staphylococcus aureus (10 vs 2 days, p ≤ 0.001, and 35 vs 14%, p ≤ 0.001). This is, to date, the largest study on IE due to HACEK. Aggregatibacter was the most common cause of IE within the group. The condition has a subacute onset and often strikes in patients with prosthetic valves, and the mortality rate is relatively low.

scholarly journals Catalytic Properties and Specificity of the Extracellular Nuclease of Staphylococcus aureus

1967 ◽  
Vol 242 (7) ◽  
pp. 1541-1547 ◽  
Author(s):  
Pedro Cuatrecasas ◽  
Sara Fuchs ◽  
Christian B. Anfinsen
Keyword(s):  
Staphylococcus Aureus ◽  
Catalytic Properties ◽  
Extracellular Nuclease

scholarly journals In situ regeneration of bioactive coatings enabled by an evolved Staphylococcus aureus sortase A

2016 ◽  
Vol 7 (1) ◽  
Author(s):  
Hyun Ok Ham ◽  
Zheng Qu ◽  
Carolyn A. Haller ◽  
Brent M. Dorr ◽  
Erbin Dai ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Sortase A ◽  
Bioactive Coatings ◽  
In Situ Regeneration

Influence of the Copper(II) Oxide Dispersion on its Catalytic Properties in Carbon Monoxide Oxidation: A Comparative Study by Using Two Types of Catalytic Reactors

ChemCatChem ◽  
2016 ◽  
Vol 8 (22) ◽  
pp. 3546-3555 ◽  
Author(s):  
Dmitry A. Svintsitskiy ◽  
Ilya Yu. Pakharukov ◽  
Elena M. Slavinskaya ◽  
Tatyana Yu. Kardash ◽  
Valentin N. Parmon ◽  
...  
Keyword(s):  
Carbon Monoxide ◽  
Comparative Study ◽  
Catalytic Properties ◽  
Carbon Monoxide Oxidation ◽  
Oxide Dispersion ◽  
Catalytic Reactors

Virulence Factors of Staphylococcus aureus in the Pathogenesis of Endocarditis A Comparative Study of Clinical Isolates

1998 ◽  
Vol 287 (4) ◽  
pp. 433-447 ◽  
Author(s):  
Shahin Nozohoor ◽  
Anders Heimdahl ◽  
Patricia Colque-Navarro ◽  
Inger Julander ◽  
Bo Söderquist ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Comparative Study ◽  
Virulence Factors ◽  
Clinical Isolates
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