scholarly journals Chemical probes for molecular imaging and detection of hydrogen sulfide and reactive sulfur species in biological systems

2015 ◽  
Vol 44 (14) ◽  
pp. 4596-4618 ◽  
Author(s):  
Vivian S. Lin ◽  
Wei Chen ◽  
Ming Xian ◽  
Christopher J. Chang
Keyword(s):  
Hydrogen Sulfide ◽  
Molecular Imaging ◽  
Live Cell Imaging ◽  
Cell Imaging ◽  
Biological Systems ◽  
Molecular Probes ◽  
Chemical Probes ◽  
Sulfur Species ◽  
Sulfane Sulfur ◽  
Reactive Sulfur Species

This review highlights progress in the development of molecular probes for live cell imaging of hydrogen sulfide and other reactive sulfur species, including sulfite, bisulfite, sulfane sulfur species, and S-nitrosothiols.

scholarly journals Metabolism of hydrogen sulfide (H2S) and Production of Reactive Sulfur Species (RSS) by superoxide dismutase

Redox Biology ◽  
2018 ◽  
Vol 15 ◽  
pp. 74-85 ◽  
Author(s):  
Kenneth R. Olson ◽  
Yan Gao ◽  
Faihaan Arif ◽  
Kanika Arora ◽  
Shivali Patel ◽  
...  
Keyword(s):  
Superoxide Dismutase ◽  
Hydrogen Sulfide ◽  
Sulfur Species ◽  
Reactive Sulfur Species

A new ESIPT-based fluorescent probe for highly selective and sensitive detection of hydrogen sulfide and its application in live-cell imaging

2017 ◽  
Vol 41 (3) ◽  
pp. 1119-1123 ◽  
Author(s):  
Bo Chen ◽  
Jing Huang ◽  
Huiqing Geng ◽  
Lingli Xuan ◽  
Tengfei Xu ◽  
...  
Keyword(s):  
Hydrogen Sulfide ◽  
Fluorescent Probe ◽  
Live Cell Imaging ◽  
Cell Imaging ◽  
Live Cell ◽  
Sensitive Detection

A new ESIPT-based fluorescent probe for the sensitive detection of hydrogen sulfide has been reasonably designed and developed.

Two-Input Fluorescent Probe for Thiols and Hydrogen Sulfide Chemosensing and Live Cell Imaging

ACS Sensors ◽  
2016 ◽  
Vol 1 (7) ◽  
pp. 888-895 ◽  
Author(s):  
Chun-Guang Dai ◽  
Xiu-Ling Liu ◽  
Xiao-Jiao Du ◽  
Yan Zhang ◽  
Qin-Hua Song
Keyword(s):  
Hydrogen Sulfide ◽  
Fluorescent Probe ◽  
Live Cell Imaging ◽  
Cell Imaging ◽  
Live Cell

scholarly journals Hydrogen Sulfide and Reactive Sulfur Species Impact Proteome S-Sulfhydration and Global Virulence Regulation in Staphylococcus aureus

2017 ◽  
Vol 3 (10) ◽  
pp. 744-755 ◽  
Author(s):  
Hui Peng ◽  
Yixiang Zhang ◽  
Lauren D. Palmer ◽  
Thomas E. Kehl-Fie ◽  
Eric P. Skaar ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Hydrogen Sulfide ◽  
Sulfur Species ◽  
Virulence Regulation ◽  
Reactive Sulfur Species

scholarly journals Reactive Sulfur Species

2020 ◽  
Vol 40 (4) ◽  
pp. 874-884 ◽  
Author(s):  
Gopi K. Kolluru ◽  
Xinggui Shen ◽  
Christopher G. Kevil
Keyword(s):  
Hydrogen Sulfide ◽  
Biological Activities ◽  
Protein Biosynthesis ◽  
Chemical Properties ◽  
Trna Synthetase ◽  
Future Research ◽  
Sulfur Species ◽  
Biologically Relevant ◽  
Transsulfuration Pathway ◽  
Reactive Sulfur Species

Hydrogen sulfide has emerged as an important gaseous signaling molecule and a regulator of critical biological processes. However, the physiological significance of hydrogen sulfide metabolites such as persulfides, polysulfides, and other reactive sulfur species (RSS) has only recently been appreciated. Emerging evidence suggests that these RSS molecules may have similar or divergent regulatory roles compared with hydrogen sulfide in various biological activities. However, the chemical nature of persulfides and polysulfides is complex and remains poorly understood within cardiovascular and other pathophysiological conditions. Recent reports suggest that RSS can be produced endogenously, with different forms having unique chemical properties and biological implications involving diverse cellular responses such as protein biosynthesis, cell-cell barrier functions, and mitochondrial bioenergetics. Enzymes of the transsulfuration pathway, CBS (cystathionine beta-synthase) and CSE (cystathionine gamma-lyase), may also produce RSS metabolites besides hydrogen sulfide. Moreover, CARSs (cysteinyl-tRNA synthetase) are also able to generate protein persulfides via cysteine persulfide (CysSSH) incorporation into nascently formed polypeptides suggesting a new biologically relevant amino acid. This brief review discusses the biochemical nature and potential roles of RSS, associated oxidative stress redox signaling, and future research opportunities in cardiovascular disease.

A hexaphenylbenzene based AIEE active two photon probe for the detection of hydrogen sulfide with tunable self-assembly in aqueous media and application in live cell imaging

2015 ◽  
Vol 51 (85) ◽  
pp. 15570-15573 ◽  
Author(s):  
Subhamay Pramanik ◽  
Vandana Bhalla ◽  
Hwan Myung Kim ◽  
Hardev Singh ◽  
Hyo Won Lee ◽  
...  
Keyword(s):  
Hydrogen Sulfide ◽  
Hela Cells ◽  
Self Assembly ◽  
Live Cell Imaging ◽  
Cell Imaging ◽  
Aqueous Media ◽  
Live Cell ◽  
Two Photon ◽  
Self Assembled

AIEE active HPB based TPE probe exhibited modulation of self-assembled architecture in presence of H2S and was utilized for TPM imaging for detection of H2S in HeLa cells.

scholarly journals Acyl Selenyl Sulfides as the Precursors for Reactive Sulfur Species (Hydrogen Sulfide, Polysulfide, and Selenyl Sulfide)

2019 ◽  
Vol 21 (14) ◽  
pp. 5685-5688 ◽  
Author(s):  
Akil Hamsath ◽  
Yingying Wang ◽  
Chun-tao Yang ◽  
Shi Xu ◽  
Danica Cañedo ◽  
...  
Keyword(s):  
Hydrogen Sulfide ◽  
Sulfur Species ◽  
Reactive Sulfur Species

scholarly journals Development of a reversible fluorescent probe for reactive sulfur species, sulfane sulfur, and its biological application

2017 ◽  
Vol 53 (6) ◽  
pp. 1064-1067 ◽  
Author(s):  
Yoko Takano ◽  
Kenjiro Hanaoka ◽  
Kazuhito Shimamoto ◽  
Ryo Miyamoto ◽  
Toru Komatsu ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Biological Application ◽  
Sulfur Species ◽  
Sulfane Sulfur ◽  
Concentration Changes ◽  
Reactive Sulfur Species

We developed a reversible fluorescent probe for sulfane sulfur. This probe enabled us to monitor concentration changes of sulfane sulfur.

An ICT-based colorimetric and ratiometric fluorescent probe for hydrogen sulfide and its application in live cell imaging

RSC Advances ◽  
2016 ◽  
Vol 6 (39) ◽  
pp. 33031-33035 ◽  
Author(s):  
Jinglu Wang ◽  
Yu Chen ◽  
Chengyu Yang ◽  
Tin Wei ◽  
Yifeng Han ◽  
...  
Keyword(s):  
Hydrogen Sulfide ◽  
Fluorescent Probe ◽  
Live Cell Imaging ◽  
Cell Imaging ◽  
Live Cell ◽  
Ratiometric Fluorescent Probe

A new naphthalimide-based fluorescent probe for the detection of hydrogen sulfide has been reasonably designed and developed.

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