Hole delocalization over adenine tracts in single stranded DNA oligonucleotides

2015 ◽  
Vol 17 (6) ◽  
pp. 4750-4756 ◽  
Author(s):  
Amedeo Capobianco ◽  
Tonino Caruso ◽  
Andrea Peluso
Keyword(s):  
Spin Density ◽  
Single Stranded Dna ◽  
Dna Oligomers ◽  
Dna Oligonucleotides

The spin density of oxidized single stranded DNA oligomers is distributed over adenine tracts forming delocalized polarons.

Selective Functionalization at N2-Position of Guanine in Oligonucleotides via Reductive Amination

2020 ◽  
Author(s):  
Bapurao Bhoge ◽  
Ishu Saraogi
Keyword(s):  
Organic Chemistry ◽  
Chemical Biology ◽  
Reductive Amination ◽  
The Other ◽  
Dna Oligomers ◽  
Site Specific ◽  
Wide Applicability ◽  
Dna Oligonucleotides ◽  
Selective Functionalization

Chemo- and site-specific modifications in oligonucleotides have wide applicability as mechanistic probes in chemical biology. Here we have employed a classical reaction in organic chemistry, reductive amination, to selectively functionalize the N<sup>2</sup>-amine of guanine/2’-deoxyguanine monophosphate. This method specifically modifies guanine in several tested DNA oligonucleotides, while leaving the other bases unaffected. Using this approach, we have successfully incorporated desired handles chemoselectively into DNA oligomers.

Gene Modification in Embryonic Stem Cells by Single-Stranded DNA Oligonucleotides

2009 ◽  
pp. 79-99 ◽  
Author(s):  
Marieke Aarts ◽  
Marleen Dekker ◽  
Rob Dekker ◽  
Sandra de Vries ◽  
Anja van der Wal ◽  
...  
Keyword(s):  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Embryonic Stem ◽  
Gene Modification ◽  
Single Stranded Dna ◽  
Dna Oligonucleotides

Spectroscopic and microscopic analyses of rod‐shaped gold nanoparticles interacting with single‐stranded DNA oligonucleotides

2013 ◽  
Vol 7 (2) ◽  
pp. 42-49 ◽  
Author(s):  
Reza Saber ◽  
Zahra Shakoori ◽  
Saeed Sarkar ◽  
Gholamreza Tavoosidana ◽  
Sharmin Kharrazi ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Single Stranded Dna ◽  
Dna Oligonucleotides

Evidence of Impurities in Thiolated Single-Stranded DNA Oligomers and Their Effect on DNA Self-Assembly on Gold

Langmuir ◽  
2005 ◽  
Vol 21 (11) ◽  
pp. 5134-5141 ◽  
Author(s):  
Chi-Ying Lee ◽  
Heather E. Canavan ◽  
Lara J. Gamble ◽  
David G. Castner
Keyword(s):  
Self Assembly ◽  
Single Stranded Dna ◽  
Dna Oligomers

The adsorption of short single-stranded DNA oligomers to mineral surfaces

Chemosphere ◽  
2011 ◽  
Vol 83 (11) ◽  
pp. 1560-1567 ◽  
Author(s):  
H. James Cleaves ◽  
Ellen Crapster-Pregont ◽  
Caroline M. Jonsson ◽  
Christopher L. Jonsson ◽  
Dimitri A. Sverjensky ◽  
...  
Keyword(s):  
Mineral Surfaces ◽  
Single Stranded Dna ◽  
Dna Oligomers
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