Pressure-induced molten globule state of human acetylcholinesterase: structural and dynamical changes monitored by neutron scattering

2015 ◽  
Vol 17 (5) ◽  
pp. 3157-3163 ◽  
Author(s):  
J. Marion ◽  
M. Trovaslet ◽  
N. Martinez ◽  
P. Masson ◽  
R. Schweins ◽  
...  
Keyword(s):  
Hydrostatic Pressure ◽  
Neutron Scattering ◽  
High Hydrostatic Pressure ◽  
Molten Globule ◽  
Molten Globule State ◽  
Structure And Dynamics

We used neutron scattering to study the effects of high hydrostatic pressure on the structure and dynamics of human acetylcholinesterase (hAChE).

The impact of high hydrostatic pressure on structure and dynamics of β-lactoglobulin

2013 ◽  
Vol 1830 (10) ◽  
pp. 4974-4980 ◽  
Author(s):  
Daniela Russo ◽  
Maria Grazia Ortore ◽  
Francesco Spinozzi ◽  
Paolo Mariani ◽  
Camille Loupiac ◽  
...  
Keyword(s):  
Hydrostatic Pressure ◽  
High Hydrostatic Pressure ◽  
Structure And Dynamics ◽  
The Impact ◽  
Β Lactoglobulin

scholarly journals Structural Effects of High Hydrostatic Pressure on Human Low Density Lipoprotein Revealed by Small Angle X-ray and Neutron Scattering

2016 ◽  
Vol 110 (3) ◽  
pp. 255a-256a
Author(s):  
Bernhard Lehofer ◽  
Maksym Golub ◽  
Karin Kornmueller ◽  
Manfred Kriechbaum ◽  
Nicolas Martinez ◽  
...  
Keyword(s):  
Hydrostatic Pressure ◽  
Neutron Scattering ◽  
Small Angle ◽  
High Hydrostatic Pressure ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Low Density ◽  
Structural Effects ◽  
X Ray

High hydrostatic pressure effects investigated by neutron scattering on lipid multilamellar vesicles

2013 ◽  
Vol 15 (48) ◽  
pp. 20951 ◽  
Author(s):  
Marcus Trapp ◽  
Jérémie Marion ◽  
Moeava Tehei ◽  
Bruno Demé ◽  
Thomas Gutberlet ◽  
...  
Keyword(s):  
Hydrostatic Pressure ◽  
Neutron Scattering ◽  
High Hydrostatic Pressure ◽  
Pressure Effects ◽  
Multilamellar Vesicles

scholarly journals Deep Sea Microbes Probed by Incoherent Neutron Scattering Under High Hydrostatic Pressure

2014 ◽  
Vol 228 (10-12) ◽  
Author(s):  
Judith Peters ◽  
Nicolas Martinez ◽  
Grégoire Michoud ◽  
Anaïs Cario ◽  
Bruno Franzetti ◽  
...  
Keyword(s):  
High Pressure ◽  
Hydrostatic Pressure ◽  
Neutron Scattering ◽  
Deep Sea ◽  
High Hydrostatic Pressure ◽  
Deep Biosphere ◽  
Incoherent Neutron Scattering ◽  
Incoherent Neutron ◽  
High Pressure Environment ◽  
Marine Biosphere

AbstractThe majority of the biosphere is a high pressure environment. Around 70% of the marine biosphere lies at depths below 1000 m, i.e. at pressures of 100 bars or higher. To survive in these environments, deep-biosphere organisms have adapted to life at high pressure.

High hydrostatic pressure equipment for neutron scattering studies of samples in solutions

2012 ◽  
Vol 32 (1) ◽  
pp. 97-102 ◽  
Author(s):  
Judith Peters ◽  
Marcus Trapp ◽  
Darren Hughes ◽  
Steven Rowe ◽  
Bruno Demé ◽  
...  
Keyword(s):  
Hydrostatic Pressure ◽  
Neutron Scattering ◽  
High Hydrostatic Pressure

Structure and dynamics of the acid-denatured molten globule state of .alpha.-lactalbumin: a two-dimensional NMR study

Biochemistry ◽  
1993 ◽  
Vol 32 (7) ◽  
pp. 1707-1718 ◽  
Author(s):  
Andrei T. Alexandrescu ◽  
Philip A. Evans ◽  
Maureen Pitkeathly ◽  
Jean Baum ◽  
Christopher M. Dobson
Keyword(s):  
Molten Globule ◽  
Two Dimensional ◽  
Molten Globule State ◽  
Structure And Dynamics ◽  
Nmr Study ◽  
Alpha Lactalbumin

Survival of mouse blastocysts after low-temperature preservation under high pressure

2004 ◽  
Vol 52 (4) ◽  
pp. 479-487 ◽  
Author(s):  
Cs. Pribenszky ◽  
M. Molnár ◽  
S. Cseh ◽  
L. Solti
Keyword(s):  
Phase Transition ◽  
Hydrostatic Pressure ◽  
Low Temperature ◽  
High Hydrostatic Pressure ◽  
Room Temperature ◽  
Freezing Point ◽  
Significant Loss ◽  
Embryo Cryopreservation ◽  
Subzero Temperatures ◽  
Survival Capacity

Cryoinjuries are almost inevitable during the freezing of embryos. The present study examines the possibility of using high hydrostatic pressure to reduce substantially the freezing point of the embryo-holding solution, in order to preserve embryos at subzero temperatures, thus avoiding all the disadvantages of freezing. The pressure of 210 MPa lowers the phase transition temperature of water to -21°C. According to the results of this study, embryos can survive in high hydrostatic pressure environment at room temperature; the time embryos spend under pressure without significant loss in their survival could be lengthened by gradual decompression. Pressurisation at 0°C significantly reduced the survival capacity of the embryos; gradual decompression had no beneficial effect on survival at that stage. Based on the findings, the use of the phenomena is not applicable in this form, since pressure and low temperature together proved to be lethal to the embryos in these experiments. The application of hydrostatic pressure in embryo cryopreservation requires more detailed research, although the experience gained in this study can be applied usefully in different circumstances.

Effect of High Hydrostatic Pressure on Endothelial Lipase Expression*

2010 ◽  
Vol 37 (6) ◽  
pp. 641-645 ◽  
Author(s):  
Can-Xin XU ◽  
Chun WANG ◽  
Bing-Yang ZHU ◽  
Zhi-Ping GAO ◽  
Di-Xian LUO ◽  
...  
Keyword(s):  
Hydrostatic Pressure ◽  
High Hydrostatic Pressure ◽  
Endothelial Lipase ◽  
Lipase Expression
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