scholarly journals Non-linear infrared spectroscopy of the water bending mode: direct experimental evidence of hydration shell reorganization?

2014 ◽  
Vol 16 (26) ◽  
pp. 13172-13181 ◽  
Author(s):  
Lev Chuntonov ◽  
Revati Kumar ◽  
Daniel G. Kuroda
Keyword(s):  
Infrared Spectroscopy ◽  
Experimental Evidence ◽  
Hydration Shell ◽  
Direct Experimental Evidence ◽  
Bending Mode ◽  
Non Linear

Direct experimental evidence for the non-linear elasticity of multi-functional alloy Ti2448

2021 ◽  
Vol 24 ◽  
pp. 100672
Author(s):  
Jiaming Zhu ◽  
Peijian Chen ◽  
He Huang ◽  
Gang Zhang ◽  
Feng Hao ◽  
...  
Keyword(s):  
Experimental Evidence ◽  
Linear Elasticity ◽  
Direct Experimental Evidence ◽  
Non Linear

Overexpression of cysteine dioxygenase reduces intracellular cysteine and glutathione pools in HepG2/C3A cells

2007 ◽  
Vol 293 (1) ◽  
pp. E62-E69 ◽  
Author(s):  
John E. Dominy ◽  
Jesse Hwang ◽  
Martha H. Stipanuk
Keyword(s):  
Steady State ◽  
Experimental Evidence ◽  
Cysteine Dioxygenase ◽  
Wild Type ◽  
Hepatic Expression ◽  
Direct Experimental Evidence ◽  
Homeostatic Response ◽  
Catabolic Enzyme ◽  
In Cells

Cysteine levels are carefully regulated in mammals to balance metabolic needs against the potential for cytotoxicity. It has been postulated that one of the major regulators of intracellular cysteine levels in mammals is cysteine dioxygenase (CDO). Hepatic expression of this catabolic enzyme increases dramatically in response to increased cysteine availability and may therefore be part of a homeostatic response to shunt excess toxic cysteine to more benign metabolites such as sulfate or taurine. Direct experimental evidence, however, is lacking to support the hypothesis that CDO is capable of altering steady-state intracellular cysteine levels. In this study, we expressed either the wild-type (WT) or a catalytically inactivated mutant (H86A) isoform of CDO in HepG2/C3A cells (which do not express endogenous CDO protein) and cultured them in different concentrations of extracellular cysteine. WT CDO, but not H86A CDO, was capable of reducing intracellular cysteine levels in cells incubated in physiologically relevant concentrations of cysteine. WT CDO also decreased the glutathione pool and potentiated the toxicity of CdCl2. These results demonstrate that CDO is capable of altering intracellular cysteine levels as well as glutathione levels.

Large magnetostriction and direct experimental evidence for anisotropy compensation in Tb0.4−xNdxDy0.6(Fe0.8Co0.2)1.93 Laves compounds

2014 ◽  
Vol 137 ◽  
pp. 274-276 ◽  
Author(s):  
J.J. Liu ◽  
Z.B. Pan ◽  
X.Y. Liu ◽  
Z.R. Zhang ◽  
X.H. Song ◽  
...  
Keyword(s):  
Experimental Evidence ◽  
Direct Experimental Evidence
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