Self-assembly of long chain fatty acids: effect of a methyl branch

2014 ◽  
Vol 16 (33) ◽  
pp. 17869-17882 ◽  
Author(s):  
Jonathan F. D. Liljeblad ◽  
Eric Tyrode ◽  
Esben Thormann ◽  
Ann-Claude Dublanchet ◽  
Gustavo Luengo ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Self Assembly ◽  
Molecular Conformation ◽  
Long Chain Fatty Acids ◽  
Methyl Branch ◽  
Straight Chain ◽  
Branched Fatty Acids ◽  
Methyl Branched Fatty Acids ◽  
Long Chain ◽  
Chain Fatty Acids

The morphology and molecular conformation of monolayers of straight chain and methyl-branched fatty acids have been investigated by VSFS and AFM, revealing domains in the latter case, due to inverse micellar packing constraints.

Mammalian Pheromone Studies, V*. Compounds from the Preorbital Gland of the Grysbok, Raphicerus melanotis

1981 ◽  
Vol 36 (3-4) ◽  
pp. 344-346 ◽  
Author(s):  
B. V. Burger ◽  
Maritha le Roux ◽  
H. S. C. Spies ◽  
Verona Truter ◽  
R. C. Bigalke ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Formic Acid ◽  
Long Chain Fatty Acids ◽  
Straight Chain ◽  
Unsaturated Alcohols ◽  
Preorbital Secretion ◽  
Long Chain ◽  
Chain Fatty Acids

A series of straight chain ketones, saturated, unsaturated, and doubly unsaturated alcohols, saturated and unsaturated formiates, hexanal, formic acid, and a number of long chain fatty acids have been identified in the preorbital secretion of the grysbok, Raphicerus melanotis

scholarly journals Self-Assembly of Bilayer Vesicles Made of Saturated Long Chain Fatty Acids

Langmuir ◽  
2016 ◽  
Vol 32 (2) ◽  
pp. 401-410 ◽  
Author(s):  
Jean-Paul Douliez ◽  
Bérénice Houinsou Houssou ◽  
A-Laure Fameau ◽  
Laurence Navailles ◽  
Frédéric Nallet ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Self Assembly ◽  
Long Chain Fatty Acids ◽  
Long Chain ◽  
Chain Fatty Acids

scholarly journals Differential Effects of Fatty Acid Saturation and Chain Length on NASH in Juvenile Iberian Pigs

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 682-682 ◽  
Author(s):  
Kayla Dillard ◽  
Morgan Coffin ◽  
Gabriella Hernandez ◽  
Victoria Smith ◽  
Catherine Johnson ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Body Weight ◽  
Fatty Acid ◽  
Liver Injury ◽  
Olive Oil ◽  
Coconut Oil ◽  
Long Chain Fatty Acids ◽  
Medium Chain ◽  
Long Chain ◽  
Chain Fatty Acids

Abstract Objectives Non-alcoholic fatty liver disease (NAFLD) represents the major cause of pediatric chronic liver pathology in the United States. The objective of this study was to compare the relative effect of inclusion of isocaloric amounts of saturated medium-chain fatty acids (hydrogenated coconut oil), saturated long-chain fatty acids (lard) and unsaturated long-chain fatty acids (olive oil) on endpoints of NAFLD and insulin resistance. Methods Thirty-eight 15-d-old Iberian pigs were fed 1 of 4 diets containing (g/kg body weight × d) 1) control (CON; n = 8): 0 g fructose, 10.5 g fat, and 187 kcal metabolizable energy (ME), 2) lard (LAR; n = 10): 21.6 g fructose, 17.1 g fat (100% lard) and 299 kcal ME, 3) hydrogenated coconut oil (COCO; n = 10): 21.6 g fructose, 16.9 g fat (42.5% lard and 57.5% coconut oil) and 299 kcal ME, and 4) olive oil (OLV, n = 10): 21.6 g fructose, 17.1 g fat (43.5% lard and 56.5% olive oil) and 299 kcal ME, for 9 consecutive weeks. Body weight was recorded every 3 d. Serum markers of liver injury and dyslipidemia were measured on d 60 at 2 h post feeding, with all other serum measures assessed on d 70. Liver tissue was collected on d 70 for histology, triacylglyceride (TG) quantification, and metabolomics analysis. Results Tissue histology indicated the presence of steatosis in LAR, COCO and OLV compared with CON (P ≤ 0.001), with a further increase in in non-alcoholic steatohepatitis (NASH) in OLV and COCO compared with LAR (P ≤ 0.01). Alanine and aspartate aminotransferases were higher in COCO and OLV (P ≤ 0.01) than CON. All treatment groups had lower liver concentrations of methyl donor's choline and betaine versus CON, while bile acids were differentially changed (P ≤ 0.05). COCO had higher levels of TGs with less carbons (Total carbons < 52) than all other groups (P ≤ 0.05). Several long-chain acylcarnitines involved in fat oxidation were higher in OLV versus all other groups (P ≤ 0.05). Conclusions Inclusion of fats enriched in medium-chain saturated and long-chain unsaturated fatty acids in a high-fructose high-fat diet increased liver injury, compared with fats with a long-chain saturated fatty acid profile. Further research is required to investigate the mechanisms causing this difference in physiological response to these dietary fat sources. Funding Sources ARI, AcornSeekers.

Long chain fatty acids can form aggregates and affect the membrane integrity

2021 ◽  
Vol 204 ◽  
pp. 111795
Author(s):  
Gulen Melike Demirbolat ◽  
Goknil Pelin Coskun ◽  
Omer Erdogan ◽  
Ozge Cevik
Keyword(s):  
Fatty Acids ◽  
Membrane Integrity ◽  
Long Chain Fatty Acids ◽  
Long Chain ◽  
Chain Fatty Acids
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