Magnetofluorescent micellar complexes of terbium(iii) as potential bimodal contrast agents for magnetic resonance and optical imaging

2015 ◽  
Vol 51 (14) ◽  
pp. 2984-2986 ◽  
Author(s):  
Michael Harris ◽  
Sophie Carron ◽  
Luce Vander Elst ◽  
Sophie Laurent ◽  
Robert N. Muller ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Contrast Agent ◽  
Contrast Agents ◽  
Optical Imaging

Micellar nano-aggregates containing Tb(iii) have been evaluated as a single lanthanide bimodal contrast agent for magnetic resonance and optical imaging.

scholarly journals Magnetic resonance thermometry using a GdIII-based contrast agent

2021 ◽  
Vol 57 (14) ◽  
pp. 1770-1773
Author(s):  
S. A. Amali S. Subasinghe ◽  
Jonathan Romero ◽  
Cassandra L. Ward ◽  
Matthew D. Bailey ◽  
Donna R. Zehner ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Agent ◽  
Contrast Agents ◽  
Resonance Imaging ◽  
Magnetic Resonance Thermometry

The complexes described here serve as contrast agents for magnetic resonance imaging thermometry.

scholarly journals Multimodal Magnetic-Resonance/Optical-Imaging Contrast Agent Sensitive to NADH

2009 ◽  
Vol 48 (35) ◽  
pp. 6547-6551 ◽  
Author(s):  
Chuqiao Tu ◽  
Ryan Nagao ◽  
Angelique Y. Louie
Keyword(s):  
Magnetic Resonance ◽  
Contrast Agent ◽  
Optical Imaging ◽  
Imaging Contrast Agent

scholarly journals Gd- and Eu-Loaded Iron Oxide@Silica Core–Shell Nanocomposites as Trimodal Contrast Agents for Magnetic Resonance Imaging and Optical Imaging

2019 ◽  
Vol 58 (24) ◽  
pp. 16618-16628 ◽  
Author(s):  
Sonia L. C. Pinho ◽  
José Sereno ◽  
Antero J. Abrunhosa ◽  
Marie-Hélène Delville ◽  
João Rocha ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Iron Oxide ◽  
Magnetic Resonance ◽  
Contrast Agents ◽  
Optical Imaging ◽  
Core Shell ◽  
Resonance Imaging ◽  
Silica Core

scholarly journals Influence of Molecular Mobility on Contrast Efficiency of Branched Polyethylene Glycol Contrast Agent

2018 ◽  
Vol 2018 ◽  
pp. 1-8
Author(s):  
Yu-I Hsu ◽  
Atsushi Mahara ◽  
Tetsuji Yamaoka
Keyword(s):  
Polyethylene Glycol ◽  
Magnetic Resonance ◽  
Contrast Agent ◽  
Contrast Agents ◽  
Water Soluble ◽  
Mri Contrast Agent ◽  
Proton Nuclear Magnetic Resonance ◽  
Terminal Mobility ◽  
Half Height ◽  
Branched Structure

For a water-soluble polyethylene glycol (PEG) magnetic resonance imaging (MRI) contrast agent, it has been demonstrated that the contrast efficiency was increased with increased branched structure of the contrast agent. However, the cause of enhanced contrast efficiency by the branched structure has not been clarified. Hence, we investigate the cause of the contrast agent enhancement by changing the Gd introduction ratio of the eight-arm PEG from 1.97 to 4.07; furthermore, the terminal mobility of the contrast agents with different structures was evaluated using proton nuclear magnetic resonance (1H-NMR) spectroscopy. It was shown that the relaxivity and contrast luminance of the synthesized branched PEG-Gd contrast agents are larger than those of linear PEG-Gd and commercially available contrast agents. Additionally, the change in the Gd introduction ratio did not affect the contrast efficiency. The terminal mobility results measured by NMR show that the linewidth at half height became broader with an increased number of branches, implying that the mobility of branched PEG-Gd is slower than that of linear PEG-Gd. Interestingly, the linewidth at half height of different structures did not change in an organic solvent; this phenomenon appeared specifically in water. It is suggested that the stable branched structure enabled the improvement in the relaxivity and contrast luminance.

scholarly journals Polyaspartic Acid-Coated Paramagnetic Gadolinium Oxide Nanoparticles as a Dual-Modal T1 and T2 Magnetic Resonance Imaging Contrast Agent

2021 ◽  
Vol 11 (17) ◽  
pp. 8222
Author(s):  
Shanti Marasini ◽  
Huan Yue ◽  
Adibehalsadat Ghazanfari ◽  
Son Long Ho ◽  
Ji Ae Park ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Agent ◽  
Contrast Agents ◽  
Proton Spin ◽  
Water Proton ◽  
Resonance Imaging ◽  
Polyaspartic Acid ◽  
Mri Contrast ◽  
T1 And T2

Surface-coating polymers contribute to nanoparticle-based magnetic resonance imaging (MRI) contrast agents because they can affect the relaxometric properties of the nanoparticles. In this study, polyaspartic acid (PASA)-coated ultrasmall Gd2O3 nanoparticles with an average particle diameter of 2.0 nm were synthesized using the one-pot polyol method. The synthesized nanoparticles exhibited r1 and r2 of 19.1 and = 53.7 s−1mM−1, respectively, (r1 and r2 are longitudinal and transverse water–proton spin relaxivities, respectively) at 3.0 T MR field, approximately 5 and 10 times higher than those of commercial Gd-chelate contrast agents, respectively. The T1 and T2 MR images could be obtained due to an appreciable r2/r1 ratio of 2.80, indicating their potential as a dual-modal T1 and T2 MRI contrast agent.

Single-Phase Dy2O3:Tb3+Nanocrystals as Dual-Modal Contrast Agent for High Field Magnetic Resonance and Optical Imaging

2011 ◽  
Vol 23 (9) ◽  
pp. 2439-2446 ◽  
Author(s):  
Gautom Kumar Das ◽  
Yan Zhang ◽  
Loyola D’Silva ◽  
Parasuraman Padmanabhan ◽  
Boon Chin Heng ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Contrast Agent ◽  
Optical Imaging ◽  
High Field ◽  
Single Phase

scholarly journals Engineered ferritin nanocages as natural contrast agents in magnetic resonance imaging

RSC Advances ◽  
2017 ◽  
Vol 7 (55) ◽  
pp. 34892-34900 ◽  
Author(s):  
V. Nandwana ◽  
S.-R. Ryoo ◽  
S. Kanthala ◽  
A. Kumar ◽  
A. Sharma ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Agent ◽  
Contrast Agents ◽  
Magnetic Core ◽  
Mri Contrast Agent ◽  
Resonance Imaging ◽  
Mri Contrast

Here we report the development of a “natural” MRI contrast agent with tunable Fe loading and a magnetic core for magnetic resonance imaging.

A multimodal contrast agent for simultaneous magnetic resonance and optical imaging of small animal

2010 ◽  
Author(s):  
M. B. Unlu ◽  
Y. Lin ◽  
B. Grimmond ◽  
A. Sood ◽  
E. Uzgiris ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Contrast Agent ◽  
Optical Imaging ◽  
Small Animal
Sign in / Sign up

Export Citation Format

Share Document