scholarly journals Divide and control: split design of multi-input DNA logic gates

2015 ◽  
Vol 51 (5) ◽  
pp. 870-872 ◽  
Author(s):  
Yulia V. Gerasimova ◽  
Dmitry M. Kolpashchikov
Keyword(s):  

We report a strategy to design a 5-input logic gate by splitting a 2-input DNA construct.

2019 ◽  
Vol 5 (2) ◽  
pp. eaau2124 ◽  
Author(s):  
Jinyoung Seo ◽  
Sungi Kim ◽  
Ha H. Park ◽  
Da Yeon Choi ◽  
Jwa-Min Nam

Using nanoparticles as substrates for computation enables algorithmic and autonomous controls of their unique and beneficial properties. However, scalable architecture for nanoparticle-based computing systems is lacking. Here, we report a platform for constructing nanoparticle logic gates and circuits at the single-particle level on a supported lipid bilayer. Our “lipid nanotablet” platform, inspired by cellular membranes that are exploited to compartmentalize and control signaling networks, uses a lipid bilayer as a chemical circuit board and nanoparticles as computational units. On a lipid nanotablet, a single-nanoparticle logic gate senses molecules in solution as inputs and triggers particle assembly or disassembly as an output. We demonstrate a set of Boolean logic operations, fan-in/fan-out of logic gates, and a combinational logic circuit such as a multiplexer. We envisage that our approach to modularly implement nanoparticle circuits on a lipid bilayer will create new paradigms and opportunities in molecular computing, nanoparticle circuits, and systems nanoscience.


2021 ◽  
Author(s):  
Bei Li ◽  
Dongsheng Zhao ◽  
Feng Wang ◽  
Xiaoxian Zhang ◽  
Wenqian Li ◽  
...  

This review covers the latest advancements of molecular logic gates based on LMOF. The classification, design strategies, related sensing mechanisms, future developments, and challenges of LMOFs-based logic gates are discussed.


2019 ◽  
Vol 28 (10) ◽  
pp. 1950171 ◽  
Author(s):  
Vinay Kumar ◽  
Ankit Singh ◽  
Shubham Upadhyay ◽  
Binod Kumar

Power dissipation has been the prime concern for CMOS circuits. Approximate computing is a potential solution for addressing this concern as it reduces power consumption resulting in improved performance in terms of power–delay product (PDP). Decrease of power consumption in approximate computing is achieved by approximating the demand of accuracy as per the error tolerance of the system. This paper presents a new approach for designing approximate adder by introducing inexactness in the existing logic gate(s). Approximated logic gates provide flexibility in designing low power error-resilient systems depending on the error tolerance of the applications such as image processing and data mining. The proposed approximate adder (PAA) has higher accuracy than existing approximate adders with normalized mean error distance of 0.123 and 0.1256 for 16-bit and 32-bit adder, respectively, and lower PDP of 1.924E[Formula: see text]18[Formula: see text]J for 16-bit adder and 5.808E[Formula: see text]18[Formula: see text]J for 32-bit adder. The PAA also performs better than some of the recent approximate adders reported in literature in terms of layout area and delay. Performance of PAA has also been evaluated with an image processing application.


2016 ◽  
Vol 16 (5&6) ◽  
pp. 465-482
Author(s):  
Taoufik Said ◽  
Abdelhaq Chouikh ◽  
Karima Essammouni ◽  
Mohamed Bennai

We propose an effective way for realizing a three quantum logic gates (NTCP gate, NTCP-NOT gate and NTQ-NOT gate) of one qubit simultaneously controlling N target qubits based on the qubit-qubit interaction. We use the superconducting qubits in a cavity QED driven by a strong microwave field. In our scheme, the operation time of these gates is independent of the number N of qubits involved in the gate operation. These gates are insensitive to the initial state of the cavity QED and can be used to produce an analogous CNOT gate simultaneously acting on N qubits. The quantum phase gate can be realized in a time (nanosecond-scale) much smaller than decoherence time and dephasing time (microsecond-scale) in cavity QED. Numerical simulation under the influence of the gate operations shows that the scheme could be achieved efficiently within current state-of-the-art technology.


2019 ◽  
Vol 43 (32) ◽  
pp. 12734-12743 ◽  
Author(s):  
Mahesh P. Bhat ◽  
Madhuprasad Kigga ◽  
Harshith Govindappa ◽  
Pravin Patil ◽  
Ho-Young Jung ◽  
...  

A reversible chemosensor for the development of a multi-input molecular logic gate was shown.


2019 ◽  
Vol 16 (158) ◽  
pp. 20190190
Author(s):  
Matthew Egbert ◽  
Jean-Sébastien Gagnon ◽  
Juan Pérez-Mercader

It has been shown that it is possible to transform a well-stirred chemical medium into a logic gate simply by varying the chemistry’s external conditions (feed rates, lighting conditions, etc.). We extend this work, showing that the same method can be generalized to spatially extended systems. We vary the external conditions of a well-known chemical medium (a cubic autocatalytic reaction–diffusion model), so that different regions of the simulated chemistry are operating under particular conditions at particular times. In so doing, we are able to transform the initially uniform chemistry, not just into a single logic gate, but into a functionally integrated network of diverse logic gates that operate as a basic computational circuit known as a full-adder.


Author(s):  
Anthony M. Roy ◽  
Erik K. Antonsson ◽  
Andrew A. Shapiro

Control tasks involving dramatic non-linearities, such as decision making, can be challenging for classical design methods. However, autonomous stochastic design methods have proved effective. In particular, Genetic Algorithms (GA) that create phenotypes by the application of genotypes comprising rules are robust and highly scalable. Such encodings are useful for complex applications such as artificial neural net design. This paper outlines an evolutionary algorithm that creates C++ programs which in turn create Artificial Neural Networks (ANNs) that can functionally perform as an exclusive-OR logic gate. Furthermore, the GAs are able to create scalable ANNs robust enough to feature redundancies that allow the network to function despite internal failures.


Author(s):  
Mohamed Zanaty ◽  
Hubert Schneegans ◽  
Ilan Vardi ◽  
Simon Henein

Abstract Binary logic operations are the building blocks of computing machines. In this paper, we present a new programmable binary logic gate based on programmable multistable mechanisms (PMM), which are multistable structures whose stability behavior depends on modifiable boundary conditions as defined and analyzed in our previous work. The logical state of a PMM is defined by its stability and logical operations are implemented by modifying the stability behavior of the mechanism. Our programmable logic device has two qualitatively different sets of inputs. The first set determines the logic function to be computed. The second set represents the logical inputs. The output is a single logical value, “true” if the mechanism changes state and “false” otherwise. In this way, we are able to mechanically implement a set of binary logical operations. This implementation is validated using an analytical model characterizing the qualitative stability behavior of the mechanism. This was further verified using finite element analysis and experimental demonstration.


Author(s):  
Terry F. Bott ◽  
Stephen W. Eisenhawer ◽  
Jonathan Kingson ◽  
Brian P. Key

Tree structures that use logic gates to model system behavior have proven very useful in safety and reliability studies. In particular process trees are the basic structure used in a decision analysis methodology developed at Los Alamos called Logic Evolved Decision modeling (LED). LED TOOLS is the initial attempt to provide LED-based decision analysis tools in a state of the art software package. The initial release of the software, Version 2.0, addresses the first step in LED — determination of the possibilities. LED TOOLS is an object-oriented application written in Visual Basic for Windows NT based operating systems. It provides an innovative graphical user interface that was designed to emphasize the visual characteristics of logic trees and to make their development efficient and accessible to the subject matter experts who possess the detailed knowledge incorporated in the process trees. This eliminates the need for the current interface between subject matter experts and logic modeling experts. This paper provides an introduction to LED TOOLS. We begin with a description of the programming environment. The construction of a process tree is described and the simplicity and efficiency of the approach incorporated in the software is discussed. We consider the nature of the logical equations that the tree represents and show how solution of the equations yield natural language “paths.” Finally we discuss the planned improvements to the software.


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