N-Heterocyclic carbene-catalyzed enantioselective synthesis of functionalized cyclopentenes via α,β-unsaturated acyl azoliums

2014 ◽  
Vol 50 (93) ◽  
pp. 14539-14542 ◽  
Author(s):  
Santigopal Mondal ◽  
Santhivardhana Reddy Yetra ◽  
Atanu Patra ◽  
Sunita S. Kunte ◽  
Rajesh G. Gonnade ◽  
...  
Keyword(s):  
Enantioselective Synthesis ◽  
Malonic Ester ◽  
Benzoyl Group ◽  
Unsaturated Acyl

Highly enantioselective NHC-organocatalyzed synthesis of functionalized cyclopentenes by the reaction of modified enals with malonic ester derivatives having a γ-benzoyl group is reported.

ChemInform Abstract: N-Heterocyclic Carbene-Catalyzed Enantioselective Synthesis of Functionalized Cyclopentenes via α,β-Unsaturated Acyl Azoliums.

ChemInform ◽  
2015 ◽  
Vol 46 (15) ◽  
pp. no-no
Author(s):  
Santigopal Mondal ◽  
Santhivardhana Reddy Yetra ◽  
Atanu Patra ◽  
Sunita S. Kunte ◽  
Rajesh G. Gonnade ◽  
...  
Keyword(s):  
Enantioselective Synthesis ◽  
Unsaturated Acyl

Catalytic enantioselective synthesis of indolizino[8,7-b]indole alkaloid derivatives based on the tandem reaction of tertiary enamides

2021 ◽  
Author(s):  
Xin-Ming Xu ◽  
Ming Xie ◽  
Jiazhu Li ◽  
Mei-Xiang Wang
Keyword(s):  
Indole Alkaloid ◽  
Enantioselective Synthesis ◽  
High Yield ◽  
Tandem Reaction ◽  
Indole Derivatives

An exquisite Pybox/Cu(OTf)2-catalyzed asymmetric tandem reaction of tertiary enamides was developed, which enabled the expeditious synthesis of indolizino[8,7-b]indole derivatives in high yield, excellent enantioselectivity and diastereoselectivity.

Enantioselective Synthesis of Azamerone

2018 ◽  
Author(s):  
Matthew L. Landry ◽  
Grace McKenna ◽  
Noah Burns
Keyword(s):  
Late Stage ◽  
Cross Coupling ◽  
Enantioselective Synthesis ◽  
Selective Synthesis

A concise and selective synthesis of the dichlorinated meroterpenoid azamerone is described. The paucity of tactics for the synthesis of chiral organochlorides motivated the development of unique strategies for accessing these motifs in enantioenriched forms. The route features a novel enantioselective chloroetherification reaction, a Pd-catalyzed cross-coupling between a quinone diazide and a boronic hemiester, and a late-stage tetrazine [4+2]-cycloaddition/oxidation cascade.

Sign in / Sign up

Export Citation Format

Share Document