Synthesis of nitrogen-containing fused-polycyclic compounds from tyramine derivatives using phenol dearomatization and cascade cyclization

2014 ◽  
Vol 50 (84) ◽  
pp. 12775-12778 ◽  
Author(s):  
Takuya Yokosaka ◽  
Tetsuhiro Nemoto ◽  
Hiroki Nakayama ◽  
Naoki Shiga ◽  
Yasumasa Hamada
Keyword(s):  
Polycyclic Compounds ◽  
Cascade Cyclization

ChemInform Abstract: Rapid Access to 3-(Aminomethyl)isoquinoline-Fused Polycyclic Compounds by Copper-Catalyzed Four-Component Coupling, Cascade Cyclization, and Oxidation.

ChemInform ◽  
2010 ◽  
Vol 41 (2) ◽  
Author(s):  
Yusuke Ohta ◽  
Yushi Kubota ◽  
Tsuyoshi Watabe ◽  
Hiroaki Chiba ◽  
Shinya Oishi ◽  
...  
Keyword(s):  
Polycyclic Compounds ◽  
Cascade Cyclization ◽  
Rapid Access

A concise synthesis of indene-based polycyclic compounds via FeCl3-catalyzed cascade cyclization

2018 ◽  
Vol 5 (7) ◽  
pp. 1165-1169 ◽  
Author(s):  
Xiang Su ◽  
Panpan Wu ◽  
Wenfeng Liu ◽  
Chao Chen
Keyword(s):  
Transition Metal ◽  
Metal Salt ◽  
Bond Cleavage ◽  
Environment Friendly ◽  
Polycyclic Compounds ◽  
Propargylic Alcohols ◽  
Cascade Cyclization ◽  
Transition Metal Salt ◽  
Earth Abundant

An efficient and straightforward protocol to complex indene-based polycyclic compounds via the cascade cyclization of propargylic alcohols and alkenes was developed. The catalyst FeCl3, as an Earth-abundant and environment friendly transition metal salt, is attractive. This reaction proceeded through unusual C–C bond cleavage.

ChemInform Abstract: Synthesis of Nitrogen-Containing Fused-Polycyclic Compounds from Tyramine Derivatives Using Phenol Dearomatization and Cascade Cyclization.

ChemInform ◽  
2015 ◽  
Vol 46 (12) ◽  
pp. no-no
Author(s):  
Takuya Yokosaka ◽  
Tetsuhiro Nemoto ◽  
Hiroki Nakayama ◽  
Naoki Shiga ◽  
Yasumasa Hamada
Keyword(s):  
Polycyclic Compounds ◽  
Cascade Cyclization

Rapid Access to 3-(Aminomethyl)isoquinoline-Fused Polycyclic Compounds by Copper-Catalyzed Four-Component Coupling, Cascade Cyclization, and Oxidation

2009 ◽  
Vol 74 (16) ◽  
pp. 6299-6302 ◽  
Author(s):  
Yusuke Ohta ◽  
Yushi Kubota ◽  
Tsuyoshi Watabe ◽  
Hiroaki Chiba ◽  
Shinya Oishi ◽  
...  
Keyword(s):  
Polycyclic Compounds ◽  
Cascade Cyclization ◽  
Rapid Access

Fe-Catalyzed Conjunctive Cross-Couplings of Unactivated Alkenes with Grignard Reagents

2020 ◽  
Author(s):  
Lei Liu ◽  
Wes Lee ◽  
Cassandra R. Youshaw ◽  
Mingbin Yuan ◽  
Michael B. Geherty ◽  
...  
Keyword(s):  
Functional Groups ◽  
Cross Coupling ◽  
Alkyl Halides ◽  
Grignard Reagents ◽  
Turnover Frequency ◽  
Diverse Range ◽  
Cascade Cyclization ◽  
Radical Cascade

The first iron-catalyzed three-component cross-coupling of unactivated olefins with alkyl halides and Grignard reagents is reported. The reaction operates under fast turnover frequency and tolerates a diverse range of sp2-hybridized nucleophiles, alkyl halides, and unactivated olefins bearing diverse functional groups to yield the desired 1,2-alkylarylated products with high regiocontrol. Further, we demonstrate that this protocol is amenable for the synthesis of new (hetero)carbocycles including tetrahydrofurans and pyrrolidines via a three-component radical cascade cyclization/arylation that forges three new C-C bonds.

scholarly journals Access to Indole‐Fused Benzannulated Medium‐Sized Rings through a Gold(I)‐Catalyzed Cascade Cyclization of Azido‐Alkynes

2021 ◽  
Author(s):  
Luca C. Greiner ◽  
Shinsuke Inuki ◽  
Norihito Arichi ◽  
Shinya Oishi ◽  
Rikito Suzuki ◽  
...  
Keyword(s):  
Cascade Cyclization

Algebraic characterization of bridged polycyclic compounds

1981 ◽  
Vol 19 (5) ◽  
pp. 929-955 ◽  
Author(s):  
Ov. Mekenyan ◽  
D. Bonchev ◽  
N. Trinajsti?
Keyword(s):  
Algebraic Characterization ◽  
Polycyclic Compounds
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