scholarly journals Mechano-responsive polymer solutions based on CO2 supersaturation: shaking-induced phase transitions and self-assembly or dissociation of polymeric nanoparticles

2014 ◽  
Vol 50 (67) ◽  
pp. 9561-9564 ◽  
Author(s):  
Peter J. Roth ◽  
Jing Yang Quek ◽  
Yicheng Zhu ◽  
Bianca M. Blunden ◽  
Andrew B. Lowe
Keyword(s):  
Phase Transitions ◽  
Self Assembly ◽  
Polymer Solutions ◽  
Polymeric Nanoparticles ◽  
Nanoparticle Formation ◽  
Soda Water ◽  
Responsive Polymer

Shaking solutions of tailored (co)polymers in soda water is shown to induce precipitation, nanoparticle formation, or polymer or nanoparticle dissolution.

scholarly journals Synthesis and self-assembly of curcumin-modified amphiphilic polymeric micelles with antibacterial activity

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Caio H. N. Barros ◽  
Dishon W. Hiebner ◽  
Stephanie Fulaz ◽  
Stefania Vitale ◽  
Laura Quinn ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Self Assembly ◽  
Glycolic Acid ◽  
Extracellular Polymeric Substances ◽  
Polymeric Micelles ◽  
Polymeric Nanoparticles ◽  
Enhanced Resistance ◽  
Antimicrobial Nanoparticles ◽  
Good Penetration ◽  
Antibiofilm Agents

Abstract Background The ubiquitous nature of bacterial biofilms combined with the enhanced resistance towards antimicrobials has led to the development of an increasing number of strategies for biofilm eradication. Such strategies must take into account the existence of extracellular polymeric substances, which obstruct the diffusion of antibiofilm agents and assists in the maintenance of a well-defended microbial community. Within this context, nanoparticles have been studied for their drug delivery efficacy and easily customised surface. Nevertheless, there usually is a requirement for nanocarriers to be used in association with an antimicrobial agent; the intrinsically antimicrobial nanoparticles are most often made of metals or metal oxides, which is not ideal from ecological and biomedical perspectives. Based on this, the use of polymeric micelles as nanocarriers is appealing as they can be easily prepared using biodegradable organic materials. Results In the present work, micelles comprised of poly(lactic-co-glycolic acid) and dextran are prepared and then functionalised with curcumin. The effect of the functionalisation in the micelle’s physical properties was elucidated, and the antibacterial and antibiofilm activities were assessed for the prepared polymeric nanoparticles against Pseudomonas spp. cells and biofilms. It was found that the nanoparticles have good penetration into the biofilms, which resulted in enhanced antibacterial activity of the conjugated micelles when compared to free curcumin. Furthermore, the curcumin-functionalised micelles were efficient at disrupting mature biofilms and demonstrated antibacterial activity towards biofilm-embedded cells. Conclusion Curcumin-functionalised poly(lactic-co-glycolic acid)-dextran micelles are novel nanostructures with an intrinsic antibacterial activity tested against two Pseudomonas spp. strains that have the potential to be further exploited to deliver a secondary bioactive molecule within its core. Graphic Abstract

Chemically Responsive Polymer Inverse-Opal Photonic Crystal Films Created by a Self-Assembly Method

2016 ◽  
Vol 120 (22) ◽  
pp. 11938-11946 ◽  
Author(s):  
Huilin Zhao ◽  
Jianping Gao ◽  
Zeng Pan ◽  
Guanbo Huang ◽  
Xiaoyang Xu ◽  
...  
Keyword(s):  
Photonic Crystal ◽  
Self Assembly ◽  
Inverse Opal ◽  
Assembly Method ◽  
Responsive Polymer ◽  
Crystal Films

Peptide-Directed Self-Assembly of Functionalized Polymeric Nanoparticles Part I: Design and Self-Assembly of Peptide-Copolymer Conjugates into Nanoparticle Fibers and 3D Scaffolds

2014 ◽  
Vol 14 (6) ◽  
pp. 853-871 ◽  
Author(s):  
Xiaochu Ding ◽  
Jagadeesh Janjanam ◽  
Ashutosh Tiwari ◽  
Martin Thompson ◽  
Patricia A. Heiden
Keyword(s):  
Self Assembly ◽  
Polymeric Nanoparticles ◽  
3D Scaffolds

scholarly journals PhotoATRP Induced Self-Assembly (PhotoATR-PISA) Enables Simplified Synthesis of Responsive Polymer Nanoparticles in One-Pot

2020 ◽  
Author(s):  
Ali Shahrokhinia ◽  
Randall Scanga ◽  
Priyanka Biswas ◽  
James Reuther
Keyword(s):  
Self Assembly ◽  
Glycidyl Methacrylate ◽  
Uv Light ◽  
Copper Catalyst ◽  
Crosslinking Agent ◽  
Polymer Nanoparticles ◽  
One Pot ◽  
Responsive Polymer ◽  
Catalyst Systems ◽  
First Time

<p><b>ABSTRACT:</b> Photo-controlled atom transfer radical polymerization (PhotoATRP) was implemented, for the first time, to accomplish polymerization induced self-assembly (PISA) mediated by UV light (λ = 365 nm) using ppm levels (ca. < 20 ppm) of copper catalyst at ambient temperature. Using Cu<sup>II</sup>Br<sub>2</sub>/tris(pyridin-2-ylmethyl)amine (TPMA) catalyst systems, PISA was per-formed all in one-pot starting from synthesis of solvophilic poly(oligo(ethylene oxide) methyl ether methacrylate) (POEGMA) blocks to core-crosslinked nanoparticles (NPs) utilizing poly(glycidyl methacrylate) (PGMA) and N,N-cystamine bismethacrylamide (CBMA) as the solvophobic copolymer and crosslinking agent, respectively. Sequential chain-extensions were performed for PGMA demonstrating capabilities for accessing multi-block copolymers with temporal control via switching the UV light on and off. Further, core-crosslinking of PISA nanoparticles was performed via the slow incorporation of the CBMA enabling one-pot crosslinking during the PISA process. Finally, the disulfide installed in the CBMA core-crosslinks allowed for the stimuli-triggered dissociation of nanoparticles using DL-dithiothreitol at acidic pH.</p>

2-Aminopyrimidine-Silver(I) Based Hybrid Organic Polymers: Self-Assembly and Phase Transitions of a Novel Class of Electronic Material

2010 ◽  
Vol 22 (16) ◽  
pp. 4749-4755 ◽  
Author(s):  
Ion Stoll ◽  
Regina Brockhinke ◽  
Andreas Brockhinke ◽  
Markus Böttcher ◽  
Thomas Koop ◽  
...  
Keyword(s):  
Phase Transitions ◽  
Electronic Material ◽  
Self Assembly ◽  
Organic Polymers

Responsive Polymer Welds via Solution Casting for Stabilized Self-Assembly

2012 ◽  
Vol 4 (12) ◽  
pp. 6911-6916 ◽  
Author(s):  
Benny Chen ◽  
Carson T. Riche ◽  
Marcus Lehmann ◽  
Malancha Gupta
Keyword(s):  
Self Assembly ◽  
Solution Casting ◽  
Responsive Polymer

Solvent Effects on the Synthesis of Polymeric Nanoparticles via Block Copolymer Self-Assembly Using Microporous Membranes

2020 ◽  
Vol 1000 ◽  
pp. 324-330
Author(s):  
Sri Agustina ◽  
Masayoshi Tokuda ◽  
Hideto Minami ◽  
Cyrille Boyer ◽  
Per B. Zetterlund
Keyword(s):  
Block Copolymer ◽  
Block Copolymers ◽  
Self Assembly ◽  
Polymeric Nanoparticles ◽  
Raft Polymerization ◽  
Membrane Emulsification ◽  
Membrane Pore ◽  
Novel Technique ◽  
Wide Range ◽  
Membrane Pore Size

The self-assembly of block copolymers has attracted attention for many decades because it can yield polymeric nanoobjects with a wide range of morphologies. Membrane emulsification is a fairly novel technique for preparation of various types of emulsions, which relies on the dispersed phase passing through a membrane in order to effect droplet formation. In this study, we have prepared polymeric nanoparticles of different morphologies using self-assembly of asymmetric block copolymers in connection with membrane emulsification. Shirasu Porous Glass (SPG) membranes has been employed as the membrane emulsification equipment, and poly (oligoethylene glycol acrylate)-block-poly (styrene) (POEGA-b-PSt) copolymers prepared via RAFT polymerization. It has been found that a number of different morphologies can be achieved using this novel technique, including spheres, rods, and vesicles. Interestingly, the results have shown that the morphology can be controlled not only by adjusting experimental parameters specific to the membrane emulsification step such as membrane pore size and pressure, but also by changing the nature of organic solvent. As such, this method provides a novel route to these interesting nanoobjects, with interesting prospects in terms of exercising morphology control without altering the nature of the block copolymer itself.

Effect of Phase Transitions in Polymer Solutions on the Magnetic Response of Embedded Nanoparticles

2020 ◽  
Vol 2 (7) ◽  
pp. 2676-2685
Author(s):  
Samira Webers ◽  
Melissa Hess ◽  
Joachim Landers ◽  
Annette M. Schmidt ◽  
Heiko Wende
Keyword(s):  
Phase Transitions ◽  
Polymer Solutions ◽  
Magnetic Response ◽  
Embedded Nanoparticles

scholarly journals Autooscillations in Thermo-responsive Polymer Solutions as the Basis for a New Type of Sensor Panels

2012 ◽  
Vol 3 ◽  
pp. 577-582 ◽  
Author(s):  
I. Suleimenov ◽  
G. Mun ◽  
R. Ivlev ◽  
S. Panchenko ◽  
D. Kaldybekov
Keyword(s):  
Polymer Solutions ◽  
Responsive Polymer ◽  
New Type
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