Pentacyclic coumarin-based blue emitters – the case of bifunctional nucleophilic behavior of amidines

2014 ◽  
Vol 50 (43) ◽  
pp. 5688-5690 ◽  
Author(s):  
Yevgen M. Poronik ◽  
Daniel T. Gryko
Keyword(s):  
Carboxylic Acids ◽  
Membered Ring ◽  
Blue Emitters

Esters of coumarin-3-carboxylic acids undergo addition to DBU and DBN leading to the formation of a 6-membered ring.

Nitroxyl Catalysts for Six-Membered Ring Bromolactonization and Intermolecular Bromoesterification of Alkenes with Carboxylic Acids

2020 ◽  
Author(s):  
Katsuhiko Moriyama ◽  
Masako Kuramochi ◽  
Seiji Tsuzuki ◽  
Kozo Fujii ◽  
Takeshi Morita
Keyword(s):  
Carboxylic Acids ◽  
Membered Ring

scholarly journals The Flögel-three-component reaction with dicarboxylic acids – an approach to bis(β-alkoxy-β-ketoenamides) for the synthesis of complex pyridine and pyrimidine derivatives

2014 ◽  
Vol 10 ◽  
pp. 394-404 ◽  
Author(s):  
Mrinal K Bera ◽  
Moisés Domínguez ◽  
Paul Hommes ◽  
Hans-Ulrich Reissig
Keyword(s):  
Dft Calculations ◽  
Carboxylic Acids ◽  
Aromatic Compounds ◽  
Dicarboxylic Acids ◽  
Membered Ring ◽  
Simple Synthesis ◽  
Pyrimidine Derivatives ◽  
Three Component Reaction ◽  
Palladium Catalyzed ◽  
Pyridine And Pyrimidine Derivatives

An extension of the substrate scope of the Flögel-three-component reaction of lithiated alkoxyallenes, nitriles and carboxylic acids is presented. The use of dicarboxylic acids allowed the preparation of symmetrical bis(β-ketoenamides) from simple starting materials in moderate yields. Cyclocondensations of these enamides to 4-hydroxypyridine derivatives or to functionalized pyrimidines efficiently provided symmetrically and unsymmetrically substituted fairly complex (hetero)aromatic compounds containing up to six conjugated aryl and hetaryl groups. In addition, subsequent functionalizations of the obtained heterocycles by palladium-catalyzed couplings or by oxidations are reported. We also describe the simple synthesis of a structurally interesting macrocyclic bispyrimidine derivative incorporating a 17-membered ring, whose configuration was elucidated by DFT calculations and by subsequent reactions.

5-Membered ring heterocyclic carboxylic acids as angiotensin II antagonists

1994 ◽  
Vol 4 (1) ◽  
pp. 169-172 ◽  
Author(s):  
John Pratt ◽  
Hwan-Soo Jae ◽  
Saul Rosenberg ◽  
Ken Spina ◽  
Martin Winn ◽  
...  
Keyword(s):  
Angiotensin Ii ◽  
Carboxylic Acids ◽  
Membered Ring ◽  
Angiotensin Ii Antagonists
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