Simultaneous determination of berberine and palmatine in human plasma and in urine by capillary electrophoresis combined with polypropylene hollow fiber liquid–liquid–liquid microextraction

2014 ◽  
Vol 6 (19) ◽  
pp. 7928-7934 ◽  
Author(s):  
Tianhe Song ◽  
Kalin Yanbo Zhang ◽  
Lixing Lao ◽  
Kai Fai Lee ◽  
Sydney Chi Wai Tang ◽  
...  
Keyword(s):  
Capillary Electrophoresis ◽  
Simultaneous Determination ◽  
Human Plasma ◽  
Hollow Fiber ◽  
Liquid Microextraction

A new assay is described for the determination of alkaloids using capillary electrophoresis combined with polypropylene hollow fiber liquid–liquid–liquid microextraction.

scholarly journals Evaluation of a Hollow-Fiber Liquid-Phase Microextraction Technique for the Simultaneous Determination of PPI Drugs in Human Plasma by LC-DAD

2018 ◽  
Vol 56 (6) ◽  
pp. 564-573 ◽  
Author(s):  
Rayta Paim Horta ◽  
Bianca do Amaral ◽  
Patricio Guillermo Peralta-Zamora ◽  
Bruno José Gonçalves Silva
Keyword(s):  
Liquid Phase ◽  
Simultaneous Determination ◽  
Human Plasma ◽  
Hollow Fiber ◽  
Liquid Phase Microextraction

Ionic Liquid-based Hollow Fiber Liquid–Liquid–Liquid Microextraction Combined with Capillary Electrophoresis for the Determination of Sulfonamides in Aquaculture Waters

2019 ◽  
Vol 57 (10) ◽  
pp. 950-960
Author(s):  
Youyi Wu ◽  
Jingwen Zhou ◽  
Xuedong Wang ◽  
Zhanen Zhang ◽  
Shiqian Gao
Keyword(s):  
Ionic Liquid ◽  
Capillary Electrophoresis ◽  
Hollow Fiber ◽  
Water Samples ◽  
Extraction Temperature ◽  
Relative Standard ◽  
Liquid Microextraction ◽  
Acceptor Phase ◽  
Donor Phase

Abstract Ionic liquid-based hollow-fiber liquid–liquid–liquid microextraction (IL-HF-LLLME) coupled to capillary electrophoresis (CE) has been developed for the determination of six sulfonamides (SAs) in aquaculture waters. A series of extraction parameters was optimized to enhance the extraction efficiency, which included type and pore size of hollow fiber, type and composition of extraction solvent, pH value of donor phase, the concentration of acceptor phase and the mass ratio of donor phase to acceptor phase along with extraction temperature and time. Under optimal conditions, the IL-HF-LLLME-CE method provided a wide liner range for six SAs from 2 to 1,000 μg L−1 (r2 ≥ 0.9995), the limits of the detection from 0.25 to 0.48 and the enrichment factors from 122 to 230, respectively. Relative standard deviations for intra- and interday precision were 1.4–5.3% and 1.8–7.5% (n = 5), respectively. The proposed method was successfully applied for the determination of trace-level SAs in seven real-world aquaculture water samples with good recoveries (80.4–100.7%). Also, sulfamerazine and sulfamethoxazole were detected at the level of 0.52–1.60 μg L−1 in two water samples. Due to its good sensitivity, simple operation, short analysis time and eco-friendliness, the developed method has a great application potential in analysis of trace SA residues in aquaculture waters.

Sign in / Sign up

Export Citation Format

Share Document