High chemiluminescence activity of an FeIII–TAML activator in aqueous–organic media and its use in the determination of organic peroxides

The Analyst ◽  
2015 ◽  
Vol 140 (9) ◽  
pp. 2964-2968 ◽  
Author(s):  
Alexandra S. Demiyanova ◽  
Ivan Yu. Sakharov
Keyword(s):  
Benzoyl Peroxide ◽  
Organic Solvents ◽  
Organic Media ◽  
Organic Peroxides ◽  
Peroxidase Mimic ◽  
Butyl Hydroperoxide ◽  
Highly Active

Using FeIII–TAML, highly active peroxidase mimic, the sensitive chemiluminescence assays for the determination of benzoyl peroxide and tert-butyl hydroperoxide in the presence of organic solvents were developed.

POLAROGRAPHIC DETERMINATION OF BENZOYL PEROXIDE AND CUMENE HYDROPEROXIDE

1951 ◽  
Vol 29 (1) ◽  
pp. 54-59 ◽  
Author(s):  
Paul A. Giguère ◽  
D. Lamontagne
Keyword(s):  
Dissolved Oxygen ◽  
Benzoyl Peroxide ◽  
Mercury Electrode ◽  
Cumene Hydroperoxide ◽  
Polarographic Determination ◽  
Polarographic Method ◽  
Organic Peroxides ◽  
Half Wave ◽  
Dropping Mercury Electrode

Benzoyl peroxide and cumene hydroperoxide (CHP) are reduced at the anodically polarized dropping mercury electrode, the former at about +0.3 volt vs. S.C.E., and the latter at +0.1 v. Their half-wave potentials as well as that of the two reduction steps of dissolved oxygen are gradually shifted towards more negative values with increasing concentration of organic peroxides. The polarographic method is suitable for determining these peroxides in concentrations up to 2 × 10−3 mole per liter. Dissolved oxygen does not interfere seriously with the analyses.

UNTERSUCHUNGEN ÜBER DIE EXTRAKTION DES ROTEN KOBER-FARBSTOFFS DURCH ORGANISCHE LÖSUNGSMITTEL ZUR ÖSTROGENBESTIMMUNG IM HARN

1960 ◽  
Vol XXXV (I) ◽  
pp. 34-48 ◽  
Author(s):  
Gerd Ittrich
Keyword(s):  
Menstrual Cycle ◽  
Organic Solvents ◽  
Urine Sample ◽  
Phenol Derivatives ◽  
Organische Lösungsmittel ◽  
Colour Complex

ABSTRACT A series of organic solvents and phenol derivatives have been examined for the extraction of the pink Kober-colour complex. Optimal results could be achieved for fluorimetry by a solution of 2 % (w/v) p-nitrophenol and 1 % (v/v) ethanol in acetylenetetrabromide, when the green mercury line (546 mμ was used as primary light. The sensitivity, stability and specificity have been improved, compared with the previously described reaction. By changing the sequence of purification steps and by reducing the volume of the urine sample (5 ml) the method for the determination of total oestrogens has been simplified. Approximately 10 determinations can be done within 3–4 hours by one person. Recovery experiments and comparative determinations with a previously described method have been carried out. The excretion of total oestrogens in a complete menstrual cycle is determined with the described method.

Generic method for determination of volatile organic solvents in cosmetics

2014 ◽  
Vol 32 (11) ◽  
pp. 1251
Author(s):  
Jing DA ◽  
Xianglu HUANG ◽  
Gangli WANG ◽  
Jin CAO ◽  
Qingsheng ZHANG
Keyword(s):  
Organic Solvents ◽  
Volatile Organic

Development and Validation of a Green Analytical Method for the Determination of Norfloxacin in Raw Material by FTIR Spectrophotometry

2016 ◽  
Vol 99 (6) ◽  
pp. 1533-1536 ◽  
Author(s):  
Jéssica Sayuri Hisano Natori ◽  
Eliane Gandolpho Tótoli ◽  
Hérida Regina Nunes Salgado
Keyword(s):  
Urinary Tract ◽  
Organic Solvents ◽  
Analytical Method ◽  
Environmentally Friendly ◽  
Raw Material ◽  
Waste Generation ◽  
Ftir Spectrophotometry ◽  
Tract Infections ◽  
Development And Validation

Abstract Norfloxacin is a broad-spectrum antimicrobial agent, widely used in humans and animals for the treatment of urinary tract infections. It is a second-generation fluoroquinolone. Several analytical methods to analyze norfloxacin have been described in the literature. However, most of them are complex and require the use of large amounts of organic solvents. This paper describes the development and validation of a green analytical method for the determination of norfloxacin in raw material by FTIR spectrophotometry. This method does not require the use of organic solvents, minimizing waste generation in the process and its environmental impacts. The development of methods that promote the reduction, prevention, or elimination of waste generation has become highly attractive to the pharmaceutical industry because of the growing demand from civil society and government authorities for environmentally friendly products and services. The FTIR spectrophotometry method was validated according to International Conference on Harmonization guidelines, showing adequate linearity (r = 0.9936), precision, accuracy, and robustness. This validated method can be used as an environmentally friendly alternative for the quantification of norfloxacin in raw material in QC routine analysis.

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