scholarly journals Oncologic photodynamic diagnosis and therapy: confocal Raman/fluorescence imaging of metal phthalocyanines in human breast cancer tissue in vitro

The Analyst ◽  
2014 ◽  
Vol 139 (21) ◽  
pp. 5547-5559 ◽  
Author(s):  
Halina Abramczyk ◽  
Beata Brozek-Pluska ◽  
Jakub Surmacki ◽  
Jacek Musial ◽  
Radzislaw Kordek

Raman microspectroscopy and confocal Raman imaging combined with confocal fluorescence were used to study the distribution and aggregation of aluminum tetrasulfonated phthalocyanine (AlPcS4) in breast tissues.

1987 ◽  
Vol 28 (5) ◽  
pp. 513-520 ◽  
Author(s):  
Michael Levin ◽  
Judith Weisz ◽  
Quang D. Bui ◽  
Richard J. Santen

The Lancet ◽  
1970 ◽  
Vol 295 (7652) ◽  
pp. 868-870 ◽  
Author(s):  
J. Chayen ◽  
F.P. Altmann ◽  
Lucille Bitensky ◽  
J.R. Daly

2020 ◽  
pp. 1-3
Author(s):  
Denong Wang ◽  
Yi Jiang ◽  
Denong Wang

There is a pressing need for biomarkers for targeted immunotherapy against breast cancer (BCA), the leading cause of cancer death in women. Previously, a blood group precursor O-core epitope gpC1 was found to be highly expressed in breast circulating tumor cells (BCTCs) and BCA cell lines with cancer stem cell (BCSC) features. In this pilot study, the breast tissue distribution of gpC1 was examined using tissue microarrays (TMAs). Notably, gpC1 positive cells were detected in the major histological types of neoplastic breast tissues. Conversely, none of the breast tissues derived from subjects without BCA were gpC1 positive. Thus, gpC1 expression seems to be tumor-specific but not histological type-dependent, reflecting perhaps its characteristics as a conserved epitope of oncofetal blood group precursor antigens.


Breast Cancer ◽  
1998 ◽  
Vol 5 (1) ◽  
pp. 47-52 ◽  
Author(s):  
Shunzo Kobayashi ◽  
Hirotaka Iwase ◽  
Yoshihiko Kawarada ◽  
Naoyuki Miura ◽  
Toshihiro Sugiyama ◽  
...  

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