An amorphous silicon photodiode microfluidic chip to detect nanomolar quantities of HIV-1 virion infectivity factor

The Analyst ◽  
2014 ◽  
Vol 139 (15) ◽  
pp. 3709-3713 ◽  
Author(s):  
Cláudia R. Vistas ◽  
Sandra S. Soares ◽  
Rogério M. M. Rodrigues ◽  
Virginia Chu ◽  
João P. Conde ◽  
...  

A hydrogenated amorphous silicon photosensor is coupled to a microfluidic channel functionalized with recombinant single fragment antibodies to detect nanomolar quantities of HIV-1 virion infective factor.

2007 ◽  
Vol 1004 ◽  
Author(s):  
A. Pereira ◽  
A. Pimentel ◽  
V. Chu ◽  
D. M. F. Prazeres ◽  
J. P. Conde

AbstractA hydrogenated amorphous silicon photodetector on a glass substrate is used for the integrated, real-time detection of chemiluminescent reactions in solution. The light emission at 425 nm resulting from the horseradish peroxidase-catalyzed oxidation of luminol is detected by a p-i-n amorphous silicon photodiode operated at zero bias. The limit of detection of the present device is in the range of nanomole of horseradish peroxidase per liter.


1981 ◽  
Vol 42 (C4) ◽  
pp. C4-773-C4-777 ◽  
Author(s):  
H. R. Shanks ◽  
F. R. Jeffrey ◽  
M. E. Lowry

2003 ◽  
Vol 762 ◽  
Author(s):  
Guofu Hou ◽  
Xinhua Geng ◽  
Xiaodan Zhang ◽  
Ying Zhao ◽  
Junming Xue ◽  
...  

AbstractHigh rate deposition of high quality and stable hydrogenated amorphous silicon (a-Si:H) films were performed near the threshold of amorphous to microcrystalline phase transition using a very high frequency plasma enhanced chemical vapor deposition (VHF-PECVD) method. The effect of hydrogen dilution on optic-electronic and structural properties of these films was investigated by Fourier-transform infrared (FTIR) spectroscopy, Raman scattering and constant photocurrent method (CPM). Experiment showed that although the phase transition was much influenced by hydrogen dilution, it also strongly depended on substrate temperature, working pressure and plasma power. With optimized condition high quality and high stable a-Si:H films, which exhibit σph/σd of 4.4×106 and deposition rate of 28.8Å/s, have been obtained.


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