Isotope labelling – paired homologous double neutral loss scan-mass spectrometry for profiling of metabolites with a carboxyl group

The Analyst ◽  
2014 ◽  
Vol 139 (13) ◽  
pp. 3446-3454 ◽  
Author(s):  
Yun-Qing Huang ◽  
Qiu-Yi Wang ◽  
Jia-Qi Liu ◽  
Yan-Hong Hao ◽  
Bi-Feng Yuan ◽  
...  

The development of a method for non-targeted screening of metabolites with a carboxyl group by high performance liquid chromatography-mass spectrometry with paired homologous double neutral loss scan mode afterin vitroisotope labelling was reported.

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