Colloidal Au nanoparticle-based “turn on” fluorescence imaging for in-gel protein detection

2014 ◽  
Vol 2 (18) ◽  
pp. 2654 ◽  
Author(s):  
Na Na ◽  
Jing Zhang ◽  
Ying You ◽  
Shaoqing Su ◽  
Jin Ouyang
Keyword(s):  
Fluorescence Imaging ◽  
Protein Detection ◽  
Au Nanoparticle ◽  
Turn On ◽  
Colloidal Au

Ubiquinone-BODIPY nanoparticles for tumor redox-responsive fluorescence imaging and photodynamic activity

2021 ◽  
Author(s):  
Byunghee Hwang ◽  
Tae-Il Kim ◽  
Hyunjin Kim ◽  
Sungjin Jeon ◽  
Yongdoo Choi ◽  
...  
Keyword(s):  
Fluorescence Imaging ◽  
Selective Activation ◽  
Turn On ◽  
Intracellular Environment ◽  
Redox Responsive ◽  
Photodynamic Activity

A ubiquinone-BODIPY photosensitizer self-assembles into nanoparticles (PS-Q-NPs) and undergoes selective activation within the highly reductive intracellular environment of tumors, resulting in “turn-on” fluorescence and photosensitizing activities.

scholarly journals Cu-Based Turn-on Fluorescent Sensors for Cu-rich Amyloid β Aggregates

2021 ◽  
Author(s):  
Yiran Huang ◽  
Liang Sun ◽  
Liviu M. Mirica
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Fluorescence Imaging ◽  
Protein Misfolding ◽  
Picolinic Acid ◽  
Amyloid Β ◽  
Fluorescent Sensors ◽  
Aβ Oligomers ◽  
Turn On ◽  
Aβ Aggregation

<div>Protein misfolding and metal dishomeostasis are two key</div><div>pathological factors of Alzheimer’s disease. Previous studies have showed that Cu‐mediated Aβ aggregation pathways lead to formation of neurotoxic Aβ oligomers. Herein, we reported a series of picolinic acid‐based Cu‐activatable sensors, which can be used for the fluorescence imaging of Cu‐rich Aβ aggregates.</div>

Disulfide bond-based self-crosslinked carbon-dots for turn-on fluorescence imaging of GSH in living cells

The Analyst ◽  
2020 ◽  
Vol 145 (8) ◽  
pp. 2982-2987 ◽  
Author(s):  
Jia Li ◽  
Yuhui Wang ◽  
Shan Sun ◽  
A-Man Lv ◽  
Kai Jiang ◽  
...  
Keyword(s):  
Fluorescence Imaging ◽  
Disulfide Bond ◽  
Carbon Dots ◽  
Living Cells ◽  
Turn On

A self-quenched nanoprobe built on a disulfide bond-based crosslink of carbon-dots has been constructed for intracellular GSH sensing.

scholarly journals A glutathione responsive pyrrolopyrrolidone nanotheranostic agent for turn-on fluorescence imaging guided photothermal/photodynamic cancer therapy

2019 ◽  
Vol 3 (10) ◽  
pp. 2143-2150 ◽  
Author(s):  
Jianhua Zou ◽  
Lei Xue ◽  
Nan Yang ◽  
Yanfang Ren ◽  
Zhe Fan ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Fluorescence Imaging ◽  
Therapeutic Efficacy ◽  
Turn On ◽  
Photodynamic Cancer Therapy

Herein, GSH responsive pyrrolopyrrolidone derivatives with enhanced photodynamic/photothermal therapeutic efficacy were designed, which can be used as colorimetric probes.

scholarly journals Extracting structural information of Au colloids at ultra-dilute concentrations: identification of growth during nanoparticle immobilization

2019 ◽  
Vol 1 (7) ◽  
pp. 2546-2552 ◽  
Author(s):  
George F. Tierney ◽  
Donato Decarolis ◽  
Norli Abdullah ◽  
Scott M. Rogers ◽  
Shusaku Hayama ◽  
...  
Keyword(s):  
Absorption Spectroscopy ◽  
Structural Characterization ◽  
Structural Information ◽  
Particle Growth ◽  
Au Nanoparticle ◽  
X Ray ◽  
Colloidal Au ◽  
X Ray Absorption ◽  
Au Colloids

This paper describes the structural characterization of ultra-dilute colloidal Au nanoparticle solutions using X-ray absorption spectroscopy (XAS) and the particle growth during immobilization.

A Surface-Enhanced Resonance Raman Scattering Method for the Determination of Trace Crystal Violet on Colloidal Au Nanoparticle Substrate

2013 ◽  
Vol 299 ◽  
pp. 191-194 ◽  
Author(s):  
Zhi Liang Jiang ◽  
Lu Ma ◽  
Ai Hui Liang
Keyword(s):  
Raman Scattering ◽  
Crystal Violet ◽  
Resonance Raman ◽  
Trisodium Citrate ◽  
Au Nanoparticle ◽  
Scattering Method ◽  
Resonance Raman Scattering ◽  
Buffer Solution ◽  
Surface Enhanced ◽  
Colloidal Au

Colloidal Au nanoparticles as active substrate for surface-enhanced resonance Raman scattering(SERRS) were prepared by the trisodium citrate-reduced procedure. In pH 6.6 Na2HPO4-NaH2PO4 buffer solution and in the presence of aggregation reagent NaCl, nanogolds were aggregated to form stable aggregated- nanogolds (ANG). The crystal violet (CV) adsorbed on the surface of ANG to form CV-ANG conjugates that produce strongest surface-enhanced resonance Raman scattering peak at 1616 cm-1. In the optimal condition, the SERRS intensity at 1616 cm-1 was linear to the CV concentration in the range of 2.5×10-8 -1.75×10-7 mol/L, a surface-enhanced resonance Raman scattering assay was set up for detection of trace CV, with good selectivity.

A fluorescent probe for the discrimination between Cys and GSH

2015 ◽  
Vol 7 (24) ◽  
pp. 10371-10375 ◽  
Author(s):  
Lun Song ◽  
Qian Sun ◽  
Nan Wang ◽  
Zhaoyang Chen ◽  
Weibing Zhang ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Fluorescence Imaging ◽  
Turn On ◽  
Spectral Channels

A turn-on fluorescent probe was designed and synthesized for discriminating between Cys and GSH from different spectral channels. The probe has potential in fluorescence imaging of cellular Cys.

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