The preparation and drug delivery of a graphene–carbon nanotube–Fe3O4 nanoparticle hybrid

2013 ◽  
Vol 1 (20) ◽  
pp. 2658 ◽  
Author(s):  
Xiujuan Fan ◽  
Guozheng Jiao ◽  
Lei Gao ◽  
Pengfei Jin ◽  
Xin Li
Langmuir ◽  
2012 ◽  
Vol 28 (45) ◽  
pp. 15900-15906 ◽  
Author(s):  
L. Minati ◽  
V. Antonini ◽  
M. Dalla Serra ◽  
G. Speranza

2009 ◽  
Vol 3 ◽  
pp. SART.S1050
Author(s):  
Caroline L. Strasinger ◽  
Nicole N. Scheff ◽  
Ji Wu ◽  
Bruce J. Hinds ◽  
Audra L. Stinchcomb

Transdermal systems are attractive methods of drug administration specifically when treating patients for drug addiction. Current systems however are deficient in therapies that allow variable flux values of drug, such as nicotine for smoking cessation or complex dosing regimens using clonidine when treating opioid withdrawal symptoms. Through the use of functionalized carbon nanotube (CNT) membranes, drug delivery to the skin can be controlled by applying a small electrical bias to create a programmable drug delivery system. Clearly, a transdermal patch system that can be tailored to an individual's needs will increase patient compliance as well as provide much more efficient therapy. The purpose of this paper is to discuss the applicability of using carbon nanotube membranes in transdermal systems for treatment of drug abuse.


NANO ◽  
2021 ◽  
pp. 2150106
Author(s):  
Anoop Kumar Pandey ◽  
Vijay Singh ◽  
Apoorva Dwivedi

Karanjin, phytochemical from Pongamia pinnata is reported to be effective against HIV that causes AIDS in humans, however, the delivery of this therapeutic molecule still needs improvement. Hence, this study provides a better understanding of the nonbonded interaction between an anti-HIV drug karanjin and carbon nanotube (CNT) (C56H16). The electronic structure and interaction properties of the molecule karanjin over the surface of CNT were theoretically studied in the gas phase by DFT/B3LYP/6-31G ([Formula: see text]) level of theory for the first time. The UV–Vis spectra and transitions of the karanjin drug, CNT (C56H16) and complex CNT (C-56)/karanjin in gas phase have been calculated by time-dependent density functional theory (TDDFT) for the investigation of adsorption effect. To support our hypothesis, we have performed quantum chemical analysis for CNT (C56H16)/karanjin in water and DMSO solvent. In this process, this CNT (C-56)/karanjin complex enters into affected cell in liquid medium. After that, the drug delivery system CNT (C-56) unloads karanjin at the affected site. The binding character interactive species have been determined by NBO and AIM analysis. The frontier orbital HOMO–LUMO gap, chemical softness, chemical hardness have also been calculated to understand its complete chemical properties. The outcomes from our interaction of drug karanjin with CNT (C56H16) will be instrumental for better drug delivery potential in the upcoming future.


Soft Matter ◽  
2018 ◽  
Vol 14 (16) ◽  
pp. 3151-3163 ◽  
Author(s):  
Sajjad Kavyani ◽  
Mitra Dadvar ◽  
Hamid Modarress ◽  
Sepideh Amjad-Iranagh

By coarse grained molecular dynamics, the effect of the size and hydrophilic/hydrophobic properties of the interior/exterior structures of the dendrimers in carbon nanotube–dendrimer composites has been studied, to find a stable composite with the capability to be used in drug delivery.


2008 ◽  
Vol 24 (6) ◽  
pp. 496-505 ◽  
Author(s):  
Rüdiger Klingeler ◽  
Silke Hampel ◽  
Bernd Büchner

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