Magnetic mesoporous silica-based core/shell nanoparticles for biomedical applications

RSC Advances ◽  
2013 ◽  
Vol 3 (25) ◽  
pp. 9584 ◽  
Author(s):  
Nikola Ž. Knežević ◽  
Eduardo Ruiz-Hernández ◽  
Wim E. Hennink ◽  
María Vallet-Regí
Keyword(s):  
Mesoporous Silica ◽  
Biomedical Applications ◽  
Core Shell ◽  
Shell Nanoparticles ◽  
Core Shell Nanoparticles ◽  
Magnetic Mesoporous Silica

Regulation of multifunctional mesoporous core–shell nanoparticles with luminescence and magnetic properties for biomedical applications

2014 ◽  
Vol 2 (16) ◽  
pp. 2265-2275 ◽  
Author(s):  
Xiaoqing Hu ◽  
Mingliang Wang ◽  
Fei Miao ◽  
Jingwei Ma ◽  
Hebai Shen ◽  
...  
Keyword(s):  
Magnetic Properties ◽  
Mesoporous Silica ◽  
Biomedical Applications ◽  
Imaging Agent ◽  
Core Shell ◽  
Shell Nanoparticles ◽  
Core Shell Nanoparticles ◽  
Potential Use

A new kind of Gd3+-based/mesoporous silica-coated multifunctional nanomedical platform is developed for potential use as optical-MR dual-modal imaging agent.

Synthesis, decoration, and cellular effects of magnetic mesoporous silica nanoparticles

RSC Advances ◽  
2016 ◽  
Vol 6 (62) ◽  
pp. 57275-57283 ◽  
Author(s):  
J. L. Nyalosaso ◽  
E. Rascol ◽  
C. Pisani ◽  
C. Dorandeu ◽  
X. Dumail ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Magnetic Core ◽  
Core Shell ◽  
Shell Nanoparticles ◽  
Cellular Effects ◽  
Core Shell Nanoparticles ◽  
Magnetic Mesoporous Silica

Synthesis of magnetic core@shell nanoparticles with different coatings and the study of their uptake by cells.

Radiosynthesis of Gold/Albumin Core/shell Nanoparticles for Biomedical Applications

MRS Advances ◽  
2017 ◽  
Vol 2 (49) ◽  
pp. 2675-2681 ◽  
Author(s):  
Constanza Y. Flores ◽  
Estefania Achilli ◽  
Mariano Grasselli
Keyword(s):  
Gold Nanoparticles ◽  
Biomedical Applications ◽  
Irradiation Dose ◽  
Ftir Spectrum ◽  
Core Shell ◽  
Peak Shape ◽  
Shell Nanoparticles ◽  
Plasmon Peak ◽  
Radiation Induced ◽  
Core Shell Nanoparticles

ABSTRACTGold/albumin core/shell nanoparticles (Au/AlbNPs) was prepared by a novel aggregation/crosslinking technique and characterized by several spectroscopic and microscopy methods. Albumin, in presence of gold nanoparticles (AuNPs), is aggregated by the addition of ethanol and further stabilized by radiation-induced crosslinking using a 60Co source. Nanoconstructs are characterized to determine size, morphology and optical characteristics. The Au/AlbNPs were prepared in different ethanol and albumins concentrations. Results showed that it is possible to obtain Au/AlbNPs using ethanol 30 %v/v, albumin in different concentrations and an irradiation dose of 10 kGy. Au/AlbNP plasmon peak shifted to 530 nm, keeping the typical plasmon peak shape. The size of Au/AlbNPs is approximately double respect to the naked AuNPs and they show core/shell type morphology. The main amide peaks of albumin in FTIR spectrum can be found in the spectrum of nanoconstructs.

Facile synthesis of multifunctional La1−xSrxMnO3@Au core–shell nanoparticles for biomedical applications

RSC Advances ◽  
2015 ◽  
Vol 5 (116) ◽  
pp. 95454-95462 ◽  
Author(s):  
Xiao Liu ◽  
Hong-Ling Liu ◽  
Ning Fang ◽  
Xue-Mei Li ◽  
Wei-Hua Guo ◽  
...  
Keyword(s):  
Optical Properties ◽  
Biomedical Applications ◽  
High Performance ◽  
Core Shell ◽  
Facile Synthesis ◽  
Shell Nanoparticles ◽  
Core Shell Nanoparticles

Multifunctional high-performance La1−xSrxMnO3@Au core–shell nanoparticles were synthesized by nanoemulsion with polymers, showing sharp Curie transition, excellent amphiphilic dispersibility and optical properties as well as biocompatibility.

The Preparation and Characteristic of Superparamagnetic Core/Shell Nanoparticles

2013 ◽  
Vol 274 ◽  
pp. 432-435
Author(s):  
Hong Xia Shen ◽  
Zheng Zhi Yin ◽  
Qiong Cheng
Keyword(s):  
Biomedical Applications ◽  
Superparamagnetic Nanoparticles ◽  
Bioactive Molecules ◽  
Core Shell ◽  
Shell Nanoparticles ◽  
X Ray ◽  
Transmission Electron ◽  
Vibration Sample Magnetometer ◽  
Diffraction Patterns ◽  
Core Shell Nanoparticles

Superparamagnetic core/shell nanoparticles have been prepared successfully by the reduction of Au3+ onto the surface of superparamagnetic nanoparticles. The core/shell nanoparticles were characterized by Transmission electron microscopy (TEM), X-ray powder diffraction patterns (XRD), UV–vis spectrophotometer, Vibration Sample Magnetometer(VSM) and micro-confocal Raman system. The results revealed that the prepared core/shell nanoparticles were covered by Au shell. These superparamagnetic nanoparticles can be highly sensitively detected and afford new opportunities for biomedical applications through chemical bonding of bioactive molecules with the Au shell of nanoparticles.

Synthesis and Stability of Highly Crystalline and Stable Iron/Iron Oxide Core/Shell Nanoparticles for Biomedical Applications

ChemPlusChem ◽  
2012 ◽  
Vol 77 (2) ◽  
pp. 135-140 ◽  
Author(s):  
Soshan Cheong ◽  
Peter Ferguson ◽  
Ian F. Hermans ◽  
Guy N. L. Jameson ◽  
Sujay Prabakar ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Biomedical Applications ◽  
Core Shell ◽  
Shell Nanoparticles ◽  
Iron Iron ◽  
Iron Oxide Core ◽  
Core Shell Nanoparticles

Investigation of magnetoelectric properties and biocompatibility of CoFe2O4-BaTiO3 core-shell nanoparticles for biomedical applications

2017 ◽  
Vol 122 (16) ◽  
pp. 164102 ◽  
Author(s):  
Badari Narayana Rao ◽  
P. Kaviraj ◽  
S. R. Vaibavi ◽  
Amit Kumar ◽  
Saumendra Kumar Bajpai ◽  
...  
Keyword(s):  
Biomedical Applications ◽  
Core Shell ◽  
Shell Nanoparticles ◽  
Magnetoelectric Properties ◽  
Core Shell Nanoparticles

scholarly journals Controllable Engineering and Functionalizing Nanoparticles with Specific Targeting Capability

2021 ◽  
Author(s):  
Zhanchen Guo ◽  
Rongrong Xing ◽  
Zhen Liu
Keyword(s):  
Breast Cancer ◽  
Biomedical Applications ◽  
High Specificity ◽  
Superparamagnetic Nanoparticles ◽  
Breast Cancer Cell Lines ◽  
Core Shell ◽  
Shell Nanoparticles ◽  
Specific Targeting ◽  
Dual Functional ◽  
Core Shell Nanoparticles

Abstract Due to unique properties, nanoparticles been widely used in important biomedical applications such as imaging, drug delivery and disease therapy. Targeting toward specific proteins is essential for the effective utilization of nanoparticles. However, current targeting strategies mainly rely on surface modification with bio-ligands, which often not only fail to provide desired properties but also remain challenging. Here we report an unprecedented approach, called reverse microemulsion-confined epitope-oriented surface imprinting and cladding (ROSIC), for facile, versatile and controllable engineering coreless and core/shell nanoparticles with tunable monodispersed size as well as specific targeting capability towards proteins and peptides. Via engineering coreless imprinted and cladded silica nanoparticles, the effectiveness and superiority over conventional imprinting of the proposed approach was first verified. The prepared nanoparticles exhibited both high specificity and high affinity. Using quantum dots (QDs), superparamagnetic nanoparticles, silver nanoparticles and upconverting nanoparticles as a representative set of core substrates, a variety of dual-functional single-core/shell nanoparticles were then successfully prepared. Finally, selective fluorescence imaging of triple negative breast cancer cells over other breast cancer cell lines using QD-cored nanoparticles was achieved, which well demonstrated the potential of the prepared core/shell nanoparticles in biomedical applications. Thus, this approach opened a new avenue to engineering and functionalization of advanced nanoparticles with targeting capability, holding great prospects in biomedical applications.

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