Central metabolic processes of marine macrophytic algae revealed from NMR based metabolome analysis

RSC Advances ◽  
2013 ◽  
Vol 3 (19) ◽  
pp. 7037 ◽  
Author(s):  
Vishal Gupta ◽  
Rajendra Singh Thakur ◽  
C. R. K. Reddy ◽  
Bhavanath Jha
Keyword(s):  
Metabolic Processes ◽  
Metabolome Analysis ◽  
Macrophytic Algae

Blood metabolome analysis for creating a digital image of a healthy person

2020 ◽  
Vol 66 (3) ◽  
pp. 216-223
Author(s):  
O.P. Trifonova ◽  
E.E. Balashova ◽  
D.L. Maslov ◽  
A.I. Grigoriev ◽  
A.V. Lisitsa ◽  
...  
Keyword(s):  
Blood Plasma ◽  
Healthy Volunteers ◽  
Human Blood ◽  
Digital Image ◽  
Healthy Person ◽  
Metabolic Processes ◽  
Metabolome Analysis ◽  
Blood Samples

In the frame of the work, data on the implementation of metabolomics tests in medicine have been systematized. Based on the obtained data, a set of protocols was proposed, the sequential realization of which makes it possible to conduct a blood metabolome analysis for medical purposes. Using this analysis and the number of blood samples from healthy volunteers, a prototype of a healthy person's metabolomic image has been developed; it allows visually and digitally to assess the compliance of the human blood metabolome with the norm. At the same time, 99% of the metabolic processes reflected in the blood plasma are estimated. If abnormalities are detected, the metabolomic image allows to get the value of these deviations of metabolic processes in digital terms.

scholarly journals Combined transcriptome and metabolome analysis identifies defence responses in spider mite-infested pepper (Capsicum annuum)

2019 ◽  
Vol 71 (1) ◽  
pp. 330-343 ◽  
Author(s):  
Yuanyuan Zhang ◽  
Harro J Bouwmeester ◽  
Iris F Kappers
Keyword(s):  
Secondary Metabolites ◽  
Capsicum Annuum ◽  
Spider Mite ◽  
Spider Mites ◽  
Fine Tuning ◽  
Mite Infestation ◽  
Metabolic Processes ◽  
Metabolome Analysis ◽  
Hormone Production ◽  
Defence Responses

Abstract Plants regulate responses towards herbivory through fine-tuning of defence-related hormone production, expression of defence genes, and production of secondary metabolites. Jasmonic acid (JA) plays a key role in plant–herbivorous arthropod interactions. To understand how pepper (Capsicum annuum) responds to herbivory, leaf transcriptomes and metabolomes of two genotypes different in their susceptibility to spider mites were studied. Mites induced both JA and salicylic acid (SA) signalling. However, mite infestation and exogenous JA resulted in distinct transcriptome profiles. Compared with JA, mites induced fewer differentially expressed genes involved in metabolic processes (except for genes involved in the phenylpropanoid pathway) and lipid metabolic processes. Furthermore, pathogen-related defence responses including WRKY transcription factors were more strongly induced upon mite infestation, probably as a result of induced SA signalling. Untargeted analysis of secondary metabolites confirmed that JA treatment induced larger changes in metabolism than spider mite infestation, resulting in higher terpenoid and flavonoid production. The more resistant genotype exhibited a larger increase in endogenous JA and volatile and non-volatile secondary metabolites upon infestation, which could explain its stronger defence. Reasoning that in JA–SA antagonizing crosstalk, SA defences are prioritized over JA defences, we hypothesize that lack of SA-mediated repression of JA-induced defences could result in gain of resistance towards spider mites in pepper.

Histone deacetylase 6– HDAC6– a new regulator of glucocorticoid receptor-mediated metabolic processes

2010 ◽  
Vol 5 (S 01) ◽  
Author(s):  
R Winkler ◽  
M Clemenz ◽  
M Bloch ◽  
A Foryst-Ludwig ◽  
C Böhm ◽  
...  
Keyword(s):  
Glucocorticoid Receptor ◽  
Histone Deacetylase ◽  
Histone Deacetylase 6 ◽  
Metabolic Processes

Progesterone contraceptives: a place in practical gynecology (to practitioner aid)

GYNECOLOGY ◽  
2018 ◽  
Vol 20 (3) ◽  
pp. 48-51
Author(s):  
Y E Dobrokhotova ◽  
E I Borovkova ◽  
S A Zalesskaya
Keyword(s):  
Diabetes Mellitus ◽  
Family Planning ◽  
Disease Control ◽  
Main Mechanism ◽  
Metabolic Processes ◽  
Tumor Pathology ◽  
Control And Prevention ◽  
Somatic Diseases

Progesterone-containing contraceptives do not have a significant impact on metabolic processes and can be prescribed to patients with systemic (diabetes mellitus, obesity) and other diseases. Desogestrel is a part of oral preparations in a dose of 75 mcg. The main mechanism of its contraceptive action is Suppression of ovulation (in 97% of cases). The frequency of pregnancy is 0.17 for 100 women-years. Progesterone-containing contraceptives should not be considered, as preparations of the second choice when deciding on the issue of family planning. According to the recommendations of the Center for Disease Control and Prevention organization of health, desogestrel is an acceptable contraceptive option for women with somatic diseases, defined tumor pathology and thrombotic states in the anamnesis.

Photosynthetic activity as the basis of potato productivity when using phytohormones

2020 ◽  
Author(s):  
A.V. Shitikova ◽  
◽  
A.A. Abiala
Keyword(s):  
Photosynthetic Activity ◽  
Moscow Region ◽  
Metabolic Processes ◽  
Biochemical Reactions ◽  
Podzolic Soils ◽  
Increase In Productivity

The results of studies on the role of growth biostimulants in the exogenous regulation of potato productivity on sod-podzolic soils of the Moscow region are presented.Studies have established the specificity of the action of phytohormones.The stimulating effect of the drugs manifested itself in the intensification of metabolic processes, changing the direction of biochemical reactions, which led to an increase in productivity.

Effect of Dinitrosyl Iron Complexes (NO Donors) on the Metabolic Processes of Human Fibroblasts

2018 ◽  
Vol 483 (4) ◽  
pp. 452-456
Author(s):  
A. Gizatullin ◽  
◽  
N. Akent'eva ◽  
N. Sanina ◽  
N. Shmatko ◽  
...  
Keyword(s):  
Human Fibroblasts ◽  
Iron Complexes ◽  
Dinitrosyl Iron Complexes ◽  
Metabolic Processes ◽  
No Donors ◽  
Dinitrosyl Iron
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