Polymerizable aggregation-induced emission dye-based fluorescent nanoparticles for cell imaging applications

2014 ◽  
Vol 5 (2) ◽  
pp. 356-360 ◽  
Author(s):  
Xiaoyong Zhang ◽  
Xiqi Zhang ◽  
Bin Yang ◽  
Meiying Liu ◽  
Wanyun Liu ◽  
...  
2019 ◽  
Vol 10 (17) ◽  
pp. 2162-2169 ◽  
Author(s):  
Zengfang Huang ◽  
Runze Wang ◽  
Yali Chen ◽  
Xiaobo Liu ◽  
Ke Wang ◽  
...  

This work reports the fabrication of a novel polymerizable AIE dye and its amphiphilic PEG-TS fluorescent polymers via RAFT polymerization, which were attractive for the application in cell imaging.


RSC Advances ◽  
2020 ◽  
Vol 10 (71) ◽  
pp. 43383-43388
Author(s):  
Sangpil Kim ◽  
Juhee Kim ◽  
Batakrishna Jana ◽  
Ja-Hyoung Ryu

Controlled intracellular chemical reactions to regulate cellular function remain a challenge in biology mimetic systems.


2016 ◽  
Vol 88 (15) ◽  
pp. 7853-7857 ◽  
Author(s):  
Suying Xu ◽  
Xilin Bai ◽  
Jingwen Ma ◽  
Minmin Xu ◽  
Gaofei Hu ◽  
...  

2018 ◽  
Vol 14 (10) ◽  
pp. 1745-1753 ◽  
Author(s):  
Wenkun Han ◽  
Song Zhang ◽  
Jingyu Qian ◽  
Jianxu Zhang ◽  
Xuanhang Wang ◽  
...  

2014 ◽  
Vol 2 (32) ◽  
pp. 6609-6617 ◽  
Author(s):  
Guocan Yu ◽  
Guping Tang ◽  
Feihe Huang

A ternary system of two tetraphenylethene derivatives containing naphthalene and paraquat groups, respectively, and a pillar[6]arene is utilized as an imaging agent for cancer cells.


2016 ◽  
Vol 52 (33) ◽  
pp. 5749-5752 ◽  
Author(s):  
Jiong Zhou ◽  
Bin Hua ◽  
Li Shao ◽  
Hao Feng ◽  
Guocan Yu

A host–guest inclusion complex based on a monofunctionalized pillar[5]arene and a tetraphenylethene derivative was prepared, resulting in an enhanced emission from the tetraphenylethene-based guest, which was applied in cell imaging.


The Analyst ◽  
2018 ◽  
Vol 143 (18) ◽  
pp. 4298-4305 ◽  
Author(s):  
Jiabin Qiu ◽  
Yunxiang Chen ◽  
Shengjie Jiang ◽  
Hongyu Guo ◽  
Fafu Yang

A fluorescent sensor based on aggregation-induced emission for amines was prepared and its highly sensitive detection of hydrazine and application in living cell imaging were investigated in detail.


2021 ◽  
pp. 000370282110275
Author(s):  
Rachel Rex ◽  
Soumik Siddhanta ◽  
Ishan Barman

Fluorescence imaging is a major driver of discovery in biology, and an invaluable asset in clinical diagnostics. To overcome quenching limitations of conventional fluorescent dyes and further improve intensity, nanoparticle-based constructs have been the subject of intense investigation, and within this realm, dye-doped silica-coated nanoparticles have garnered significant attention. Despite their growing popularity in research, fluorescent silica nanoparticles suffer from a significant flaw. The degradation of these nanoparticles in biological media by hydrolytic dissolution is underreported, leading to serious misinterpretations, and limiting their applicability for live cell and in vivo imaging. Here, the development of an ultra-stable, dye-embedded, silica-coated metal nanoparticle is reported, and its superior performance in long-term live cell imaging is demonstrated. While conventional dye-doped silica nanoparticles begin to degrade within an hour in aqueous media, by leveraging a modified liquid calcination process, this new construct is shown to be stable for at least 24 h. The stability of this metal-enhanced fluorescent probe in biologically relevant temperatures and media, and its demonstrated utility for cell imaging, paves the way for its future adoption in biomedical research.


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