Recent progress on asymmetric organocatalytic construction of chiral cyclohexenone skeletons

2014 ◽  
Vol 12 (16) ◽  
pp. 2499-2513 ◽  
Author(s):  
Xin Yang ◽  
Jun Wang ◽  
Pengfei Li
Keyword(s):  
Asymmetric Synthesis ◽  
Reaction Mechanisms ◽  
Recent Progress ◽  
Life Science ◽  
Synthetic Chemistry ◽  
Recent Advances

Chiral cyclohex-2-enones are important intermediates in synthetic chemistry as well as in the life science industries. In this focus review, recent advances in the organocatalytic asymmetric synthesis of chiral cyclohex-2-enone skeletons are summarized. The reaction mechanisms are also briefly discussed.

Iridium-Catalyzed Asymmetric C–H Borylation Enabled by Chiral Bidentate Boryl Ligands

Synlett ◽  
2019 ◽  
Vol 30 (19) ◽  
pp. 2107-2112 ◽  
Author(s):  
Yongjia Shi ◽  
Qian Gao ◽  
Senmiao Xu
Keyword(s):  
Drug Discovery ◽  
Asymmetric Synthesis ◽  
Synthetic Chemistry ◽  
Organoboron Compounds ◽  
Recent Advances ◽  
Optically Pure

Asymmetric synthesis of optically pure organoboron compounds is a topic that has received a number of attentions owing to their particular importance in synthetic chemistry and drug discovery. We herein highlight recent advances in the iridium-catalyzed C–H borylation of diarylmethylamines and cyclopropanes enabled by chiral bidentate boryl ligands.1 Introduction2 Ir-Catalyzed Asymmetric C(sp2)–H Borylation of Diarylmethylamines3 Ir-Catalyzed Enantioselective C(sp3)–H Borylation of Cyclopropanes4 Conclusion

Recent Advances in the Catalytic Asymmetric Construction of Phosphorus-Substituted Quaternary Carbon Stereocenters

Synthesis ◽  
2017 ◽  
Vol 50 (03) ◽  
pp. 440-469 ◽  
Author(s):  
Long Chen
Keyword(s):  
Asymmetric Synthesis ◽  
Reaction Mechanisms ◽  
Recent Progress ◽  
Biologically Active Compounds ◽  
Biologically Active ◽  
Quaternary Carbon ◽  
Active Compounds ◽  
Catalytic Asymmetric Synthesis ◽  
Stereogenic Centers ◽  
Catalytic Asymmetric

Phosphorus-substituted quaternary carbon stereocenters exist widely in drugs and biologically active compounds. Catalytic asymmetric synthesis of such quaternary carbon stereogenic centers is of significant importance, with four synthetic strategies being established. This review summarizes the recent progress in this field, including the advantages and limitations of each strategy, briefly discusses the reaction mechanisms and challenges, and outlines synthetic opportunities still open.1 Introduction2 Asymmetric Hydrophosphonylation3 Asymmetric Electrophilic Phosphination4 Asymmetric Functionalization of P-Substituted Methine Compounds5 Asymmetric Addition to α-Keto- or α-Ketiminophosphonates6 Conclusion

Catalytic, Enantioselective Diamination of Alkenes

Synthesis ◽  
2021 ◽  
Author(s):  
Scott E. Denmark ◽  
Zhong-Lin Tao
Keyword(s):  
Asymmetric Synthesis ◽  
Reaction Mechanisms ◽  
Short Review ◽  
Biologically Active Compounds ◽  
Biologically Active ◽  
Active Compounds ◽  
Recent Advances ◽  
Vicinal Diamines

AbstractEnantioselective diamination of alkenes represents one of the most straightforward methods to access enantioenriched, vicinal diamines, which are not only frequently encountered in biologically active compounds, but also have broad applications in asymmetric synthesis. Although the analogous dihydroxylation of olefins is well-established, the development of enantioselective olefin diamination lags far behind. Nevertheless, several successful methods have been developed that operate by different reaction mechanisms, including a cycloaddition pathway, a two-electron redox pathway, and a radical pathway. This short review summarizes recent advances and identifies limitations, with the aim of inspiring further developments in this area.1 Introduction2 Cycloaddition Pathway3 Two-Electron Redox Pathway3.1 Pd(0)/Pd(II) Diamination3.2 Pd(II)/Pd(IV) Diamination3.3 I(I)/I(III) Diamination3.4 Se(II)/Se(IV) Diamination4 One-Electron Radical Pathway4.1 Cu-Catalyzed Diamination4.2 Fe-Catalyzed Diamination5 Summary and Outlook

State-of-the-art advancements in photo-assisted CO2 hydrogenation: recent progress in catalyst development and reaction mechanisms

2020 ◽  
Vol 8 (47) ◽  
pp. 24868-24894
Author(s):  
Zhengyi Yang ◽  
Yuan Qi ◽  
Fenglong Wang ◽  
Zejun Han ◽  
Yanyan Jiang ◽  
...  
Keyword(s):  
Reaction Mechanisms ◽  
Recent Progress ◽  
State Of The Art ◽  
Co2 Hydrogenation ◽  
Catalyst Development ◽  
Solid Catalysts ◽  
Recent Advances

The recent advances in photo-promoted CO2 hydrogenation over solid catalysts have been reviewed.

Recent advances in radical transformations of internal alkynes

2018 ◽  
Vol 54 (77) ◽  
pp. 10791-10811 ◽  
Author(s):  
Min-Hua Huang ◽  
Wen-Juan Hao ◽  
Guigen Li ◽  
Shu-Jiang Tu ◽  
Bo Jiang
Keyword(s):  
Reaction Mechanisms ◽  
Recent Progress ◽  
Comprehensive Overview ◽  
Recent Advances ◽  
Internal Alkynes ◽  
Radical Transformation

This review highlights the recent progress in the radical transformation of internal alkynes and focuses on the reaction mechanisms by carbon/heteroatom-centered triggered additions, and offers a comprehensive overview on the existing procedures and employed methodologies.

Recent Progress in the Synthesis of Furan

2019 ◽  
Vol 16 (5) ◽  
pp. 422-452 ◽  
Author(s):  
Dau Xuan Duc
Keyword(s):  
Organic Chemistry ◽  
Natural Products ◽  
Oxygen Atom ◽  
Reaction Mechanisms ◽  
Recent Progress ◽  
Building Blocks ◽  
Synthesis Reaction ◽  
Natural Sources ◽  
New Methods ◽  
Recent Advances

Furans are five-membered aromatic heterocycles containing one oxygen atom that are important building blocks in organic chemistry, but also as natural products found in various natural sources, mostly in plants, algae and microorganisms. In this review, we discussed recent advances in the synthesis of furan compounds. Some classical methods have been modified and improved, while other new methods have been developed. A vast variety of catalysts was used for these transformations. In many studies, furan synthesis reaction mechanisms were also investigated and proposed.

Recent progress of MXenes and MXene-based nanomaterials for the electrocatalytic hydrogen evolution reaction

2021 ◽  
Author(s):  
Zhaoming Kang ◽  
Muhammad Arif Khan ◽  
Yanmei Gong ◽  
Rida Javed ◽  
Yuan Xu ◽  
...  
Keyword(s):  
Hydrogen Evolution ◽  
Hydrogen Evolution Reaction ◽  
Recent Progress ◽  
Recent Advances ◽  
Functional Mechanisms

In this review, recent advances in MXenes and MXene-based nanomaterials applied in HER electrocatalysis are overviewed in terms of their synthesis, characterization, functional mechanisms, and HERperformance/optimization.

scholarly journals Recent advances in understanding oxygen evolution reaction mechanisms over iridium oxide

2021 ◽  
Author(s):  
Takahiro Naito ◽  
Tatsuya Shinagawa ◽  
Takeshi Nishimoto ◽  
Kazuhiro Takanabe
Keyword(s):  
Reaction Mechanism ◽  
Oxygen Evolution ◽  
Oxygen Evolution Reaction ◽  
Reaction Mechanisms ◽  
State Of The Art ◽  
Iridium Oxide ◽  
The State ◽  
Computational Studies ◽  
Recent Advances ◽  
Iridium Oxides

Recent spectroscopic and computational studies concerning the oxygen evolution reaction over iridium oxides are reviewed to provide the state-of-the-art understanding of its reaction mechanism.

Enantioselective Functionalization of Prochiral Cyclobutanones and Cyclobutenones

Synlett ◽  
2021 ◽  
Author(s):  
Memg Wang ◽  
Changxu Zhong ◽  
Ping Lu
Keyword(s):  
Asymmetric Synthesis ◽  
Membered Ring ◽  
Enantioselective Synthesis ◽  
Ring Compounds ◽  
Recent Advances ◽  
Cyclobutane Derivatives

Enantioselective synthesis of cyclobutane derivatives is still a challenging topic in asymmetric synthesis. [2+2]-Cycloaddition and skeleton rearrangement are two primary strategies to this end. Recently, functionalization of cyclobutanones and cyclobutenones, which are readily available via [2+2]-cycloadditions as prochiral substrates, has emerged as a powerful tool to access versatile four-membered ring compounds. Herein, we summarize some recent advances in these areas from our and other groups.

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