Formation of a pseudo-β-hairpin motif utilizing the Ant–Pro reverse turn: consequences of stereochemical reordering

2014 ◽  
Vol 12 (5) ◽  
pp. 774-782 ◽  
Author(s):  
Roshna V. Nair ◽  
Amol S. Kotmale ◽  
Snehal A. Dhokale ◽  
Rupesh L. Gawade ◽  
Vedavadi G. Puranik ◽  
...  
Keyword(s):  
Anthranilic Acid ◽  
Loop Region ◽  
Reverse Turn ◽  
Hairpin Formation ◽  
Special Case

Herein, we report a special case of pseudo-β-hairpin formation by tetrapeptide sequences featuring a two-residue Ant–Pro dipeptide motif (Ant = anthranilic acid and Pro = proline) at the loop region.

Stereochemical Control of Hairpin Formation in β-Peptides Containing Dinipecotic Acid Reverse Turn Segments

2000 ◽  
Vol 122 (17) ◽  
pp. 3995-4004 ◽  
Author(s):  
Yong Jun Chung ◽  
Bayard R. Huck ◽  
Laurie A. Christianson ◽  
Heather E. Stanger ◽  
Susanne Krauthäuser ◽  
...  
Keyword(s):  
Stereochemical Control ◽  
Reverse Turn ◽  
Hairpin Formation

scholarly journals Stereochemical Control of Hairpin Formation in β-Peptides Containing Dinipecotic Acid Reverse Turn Segments  [J. Am. Chem. Soc.2000,122, 3995−4004].

2001 ◽  
Vol 123 (24) ◽  
pp. 5851-5851 ◽  
Author(s):  
Young Jun Chung ◽  
Bayard R. Huck ◽  
Laurie A. Christianson ◽  
Heather E. Stanger ◽  
Susanne Krauthäuser ◽  
...  
Keyword(s):  
Stereochemical Control ◽  
Reverse Turn ◽  
Hairpin Formation

scholarly journals A facile one step synthesis of N-2 substituted 3-phenyliminoisoindolinones from N-(2-carboxybenzoyl)anthranilic acid and design of reverse-turn mimetics

ARKIVOC ◽  
2009 ◽  
Vol 2009 (10) ◽  
pp. 12-24 ◽  
Author(s):  
Pradyot Koley ◽  
Arpita Dutta ◽  
Michael G. B. Drew ◽  
Sudeshna Kar ◽  
Animesh Pramanik
Keyword(s):  
Anthranilic Acid ◽  
Reverse Turn ◽  
One Step

ChemInform Abstract: Stereochemical Control of Hairpin Formation in β-Peptides Containing Dinipecotic Acid Reverse Turn Segments.

ChemInform ◽  
2010 ◽  
Vol 31 (31) ◽  
pp. no-no
Author(s):  
Yong Jun Chung ◽  
Bayard R. Huck ◽  
Laurie A. Christianson ◽  
Heather E. Stanger ◽  
Susanne Krauthaeuser ◽  
...  
Keyword(s):  
Stereochemical Control ◽  
Reverse Turn ◽  
Hairpin Formation

A β-Peptide Reverse Turn that Promotes Hairpin Formation

1998 ◽  
Vol 120 (40) ◽  
pp. 10555-10556 ◽  
Author(s):  
Yong Jun Chung ◽  
Laurie A. Christianson ◽  
Heather E. Stanger ◽  
Douglas R. Powell ◽  
Samuel H. Gellman
Keyword(s):  
Reverse Turn ◽  
Hairpin Formation

Extreme self-sacrifice beyond fusion: Moral expansiveness and the special case of allyship

2018 ◽  
Vol 41 ◽  
Author(s):  
Daniel Crimston ◽  
Matthew J. Hornsey
Keyword(s):  
General Theory ◽  
Biological Markers ◽  
Natural Environment ◽  
Relevant Dimension ◽  
Special Case

AbstractAs a general theory of extreme self-sacrifice, Whitehouse's article misses one relevant dimension: people's willingness to fight and die in support of entities not bound by biological markers or ancestral kinship (allyship). We discuss research on moral expansiveness, which highlights individuals’ capacity to self-sacrifice for targets that lie outside traditional in-group markers, including racial out-groups, animals, and the natural environment.

Determination of the phase structure of polymerblends by electron microscopy

1978 ◽  
Vol 36 (1) ◽  
pp. 492-493
Author(s):  
Dr. G. Kaemof
Keyword(s):  
Screw Extruder ◽  
Electron Microscopic ◽  
Thin Sections ◽  
Single Screw Extruder ◽  
Transmission Electron ◽  
The Matrix ◽  
Twin Screw ◽  
Special Case ◽  
Microscopic Investigations

A mixture of polycarbonate (PC) and styrene-acrylonitrile-copolymer (SAN) represents a very good example for the efficiency of electron microscopic investigations concerning the determination of optimum production procedures for high grade product properties.The following parameters have been varied:components of charge (PC : SAN 50 : 50, 60 : 40, 70 : 30), kind of compounding machine (single screw extruder, twin screw extruder, discontinuous kneader), mass-temperature (lowest and highest possible temperature).The transmission electron microscopic investigations (TEM) were carried out on ultra thin sections, the PC-phase of which was selectively etched by triethylamine.The phase transition (matrix to disperse phase) does not occur - as might be expected - at a PC to SAN ratio of 50 : 50, but at a ratio of 65 : 35. Our results show that the matrix is preferably formed by the components with the lower melting viscosity (in this special case SAN), even at concentrations of less than 50 %.

Test Validation Without Measurement

2016 ◽  
Vol 32 (3) ◽  
pp. 204-214 ◽  
Author(s):  
Emilie Lacot ◽  
Mohammad H. Afzali ◽  
Stéphane Vautier
Keyword(s):  
Test Data ◽  
Test Scores ◽  
Scientific Explanation ◽  
Test Validation ◽  
Clinical Tests ◽  
Ethical Perspective ◽  
Power Of Test ◽  
Memory Accuracy ◽  
Social Uses ◽  
Special Case

Abstract. Test validation based on usual statistical analyses is paradoxical, as, from a falsificationist perspective, they do not test that test data are ordinal measurements, and, from the ethical perspective, they do not justify the use of test scores. This paper (i) proposes some basic definitions, where measurement is a special case of scientific explanation; starting from the examples of memory accuracy and suicidality as scored by two widely used clinical tests/questionnaires. Moreover, it shows (ii) how to elicit the logic of the observable test events underlying the test scores, and (iii) how the measurability of the target theoretical quantities – memory accuracy and suicidality – can and should be tested at the respondent scale as opposed to the scale of aggregates of respondents. (iv) Criterion-related validity is revisited to stress that invoking the explanative power of test data should draw attention on counterexamples instead of statistical summarization. (v) Finally, it is argued that the justification of the use of test scores in specific settings should be part of the test validation task, because, as tests specialists, psychologists are responsible for proposing their tests for social uses.

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