Synthesis of fluorinated catharanthine analogues and investigation of their biomimetic coupling with vindoline

2013 ◽  
Vol 11 (35) ◽  
pp. 5885 ◽  
Author(s):  
Emerson Giovanelli ◽  
Lionel Moisan ◽  
Sébastien Comesse ◽  
Sébastien Leroux ◽  
Bernard Rousseau ◽  
...  
Keyword(s):  
Biomimetic Coupling

A Novel Icephobic Strategy: The Fabrication of Biomimetic Coupling Micropatterns of Superwetting Surface

2019 ◽  
Vol 6 (19) ◽  
pp. 1900864 ◽  
Author(s):  
Xinlin Li ◽  
Guoyong Wang ◽  
Bin Zhan ◽  
Shuyi Li ◽  
Zhiwu Han ◽  
...  
Keyword(s):  
Biomimetic Coupling

scholarly journals Effects of a Ferulate-Derived Dihydrobenzofuran Neolignan on Angiogenesis, Steroidogenesis, and Redox Status in a Swine Cell Model

2014 ◽  
Vol 19 (9) ◽  
pp. 1282-1289 ◽  
Author(s):  
Giuseppina Basini ◽  
Carmela Spatafora ◽  
Corrado Tringali ◽  
Simona Bussolati ◽  
Francesca Grasselli
Keyword(s):  
Cell Viability ◽  
Granulosa Cell ◽  
Cell Model ◽  
Biological Activities ◽  
Redox Status ◽  
Antiangiogenic Agents ◽  
Antiangiogenic Effect ◽  
Biological Targets ◽  
Therapeutic Compounds ◽  
Biomimetic Coupling

In the ongoing search for new therapeutic compounds, lignans and neolignans, which are widely distributed in plants, deserve special attention because of their interactions with several biological targets. Searching for potential antiangiogenic agents related to natural lignans/neolignans, we were attracted by a previously studied synthetic dihydrobenzofuran neolignan. We synthesized the compound by means of an eco-friendly, enzyme-mediated biomimetic coupling of the methyl ester of ferulic acid, and the present study was aimed to deeply investigate its effect in angiogenesis bioassays validated in our laboratory. In addition, a previously well-defined granulosa cell model was employed to evaluate the effect of dihydrobenzofuran neolignan on cell viability, steroidogenesis, and redox status. Present data support the antiangiogenic effect of this neolignan. Moreover, we demonstrate that, at least at the highest concentrations tested, dihydrobenzofuran neolignan affects granulosa cell viability and steroidogenesis. In addition, the compound inhibits generation of free radicals and stimulates scavenger enzyme activities. The present data, which are a further deepening of the evaluation of the biological activities of the dihydrobenzofuran lignan in well-defined cell models, are of interest and worthy of special attention.

Frictional Wear and Thermal Fatigue Behaviours of Biomimetic Coupling Materials for Brake Drums

2008 ◽  
Vol 5 ◽  
pp. 20-27 ◽  
Author(s):  
Yu Zhao ◽  
Lu-quan Ren ◽  
Xin Tong ◽  
Hong Zhou ◽  
Li Chen
Keyword(s):  
Thermal Fatigue ◽  
Frictional Wear ◽  
Biomimetic Coupling

Effects of shapes of biomimetic coupling units on wear resistance of 7075 aluminum alloy

2020 ◽  
Vol 121 ◽  
pp. 105786 ◽  
Author(s):  
Yuhuan Yuan ◽  
Guoping Zhao ◽  
Peng Zhang ◽  
Hong Zhou
Keyword(s):  
Wear Resistance ◽  
Aluminum Alloy ◽  
7075 Aluminum Alloy ◽  
Biomimetic Coupling

Synthesis of Difluorocatharanthine and Investigation of its Biomimetic Coupling with Vindoline

2012 ◽  
Vol 19 (4) ◽  
pp. 1170-1173 ◽  
Author(s):  
Emerson Giovanelli ◽  
Lionel Moisan ◽  
Sébastien Leroux ◽  
Sébastien Comesse ◽  
Bernard Rousseau ◽  
...  
Keyword(s):  
Biomimetic Coupling
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