scholarly journals A bivalent ligand targeting the putative mu opioid receptor and chemokine receptor CCR5 heterodimer: binding affinity versus functional activities

MedChemComm ◽  
2013 ◽  
Vol 4 (5) ◽  
pp. 847 ◽  
Author(s):  
Yunyun Yuan ◽  
Christopher K. Arnatt ◽  
Nazira El-Hage ◽  
Seth M. Dever ◽  
Joanna C. Jacob ◽  
...  
Keyword(s):  
Binding Affinity ◽  
Opioid Receptor ◽  
Chemokine Receptor ◽  
Mu Opioid Receptor ◽  
Bivalent Ligand ◽  
Mu Opioid ◽  
Functional Activities ◽  
Chemokine Receptor Ccr5 ◽  
Receptor Ccr5

scholarly journals Exploration of bivalent ligands targeting putative mu opioid receptor and chemokine receptor CCR5 dimerization

2016 ◽  
Vol 24 (22) ◽  
pp. 5969-5987 ◽  
Author(s):  
Christopher K. Arnatt ◽  
Bethany A. Falls ◽  
Yunyun Yuan ◽  
Thomas J. Raborg ◽  
Ruturaj R. Masvekar ◽  
...  
Keyword(s):  
Opioid Receptor ◽  
Chemokine Receptor ◽  
Mu Opioid Receptor ◽  
Bivalent Ligands ◽  
Mu Opioid ◽  
Chemokine Receptor Ccr5 ◽  
Receptor Ccr5

scholarly journals Design and synthesis of a bivalent probe targeting the putative mu opioid receptor and chemokine receptor CXCR4 heterodimer

2020 ◽  
Vol 11 (1) ◽  
pp. 125-131 ◽  
Author(s):  
Bethany A. Reinecke ◽  
Guifeng Kang ◽  
Yi Zheng ◽  
Samuel Obeng ◽  
Huijun Zhang ◽  
...  
Keyword(s):  
Opioid Receptor ◽  
Chemokine Receptor ◽  
Mu Opioid Receptor ◽  
Bivalent Ligand ◽  
Mu Opioid ◽  
Design And Synthesis ◽  
Chemokine Receptor Cxcr4

The first bivalent ligand targeting the putative heterodimer of the mu opioid receptor and the chemokine receptor CXCR4.

scholarly journals Bivalent Ligand Aiming Putative Mu Opioid Receptor and Chemokine Receptor CXCR4 Dimers in Opioid Enhanced HIV-1 Entry

2020 ◽  
Vol 11 (11) ◽  
pp. 2318-2324
Author(s):  
Hongguang Ma ◽  
Huiqun Wang ◽  
Mengchu Li ◽  
Victor Barreto-de-Souza ◽  
Bethany A. Reinecke ◽  
...  
Keyword(s):  
Opioid Receptor ◽  
Chemokine Receptor ◽  
Mu Opioid Receptor ◽  
Bivalent Ligand ◽  
Mu Opioid ◽  
Chemokine Receptor Cxcr4 ◽  
Hiv 1

scholarly journals Bivalent ligand that activates mu opioid receptor and antagonizes mGluR5 receptor reduces neuropathic pain in mice

Pain ◽  
2017 ◽  
Vol 158 (12) ◽  
pp. 2431-2441 ◽  
Author(s):  
Cristina D. Peterson ◽  
Kelley F. Kitto ◽  
Eyup Akgün ◽  
Mary M. Lunzer ◽  
Maureen S. Riedl ◽  
...  
Keyword(s):  
Neuropathic Pain ◽  
Opioid Receptor ◽  
Mu Opioid Receptor ◽  
Bivalent Ligand ◽  
Mu Opioid

scholarly journals Protein Kinase Cζ Mediates μ-Opioid Receptor-induced Cross-desensitization of Chemokine Receptor CCR5

2011 ◽  
Vol 286 (23) ◽  
pp. 20354-20365 ◽  
Author(s):  
Changcheng Song ◽  
Rahil T. Rahim ◽  
Penelope C. Davey ◽  
Filip Bednar ◽  
Giuseppe Bardi ◽  
...  
Keyword(s):  
Protein Kinase ◽  
Opioid Receptor ◽  
Chemokine Receptor ◽  
Chemokine Receptor Ccr5 ◽  
Μ Opioid Receptor ◽  
Receptor Ccr5
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