Assessment of crosstalks between the Snf1 kinase complex and sphingolipid metabolism in S. cerevisiae via systems biology approaches

Esra Borklu Yucel; Kutlu O. Ulgen

doi:10.1039/c3mb70248k

Assessment of crosstalks between the Snf1 kinase complex and sphingolipid metabolism in S. cerevisiae via systems biology approaches

Molecular BioSystems ◽

10.1039/c3mb70248k ◽

2013 ◽

Vol 9 (11) ◽

pp. 2914 ◽

Cited By ~ 6

Author(s):

Esra Borklu Yucel ◽

Kutlu O. Ulgen

Keyword(s):

Systems Biology ◽

Sphingolipid Metabolism ◽

Snf1 Kinase

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Integration of transcriptome data with interaction network reveals functional connections between Snf1 kinase complex and sphingolipid metabolism in S. Cerevisiae

New Biotechnology ◽

10.1016/j.nbt.2012.08.404 ◽

2012 ◽

Vol 29 ◽

pp. S145-S146

Author(s):

E. Yücel ◽

K. Ülgen

Keyword(s):

Interaction Network ◽

Sphingolipid Metabolism ◽

Transcriptome Data ◽

Snf1 Kinase ◽

Functional Connections

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Drug target identification in sphingolipid metabolism by computational systems biology tools: Metabolic control analysis and metabolic pathway analysis

Journal of Biomedical Informatics ◽

10.1016/j.jbi.2010.03.006 ◽

2010 ◽

Vol 43 (4) ◽

pp. 537-549 ◽

Cited By ~ 9

Author(s):

F. Betül Kavun Özbayraktar ◽

Kutlu Ö. Ülgen

Keyword(s):

Systems Biology ◽

Drug Target ◽

Target Identification ◽

Metabolic Control Analysis ◽

Sphingolipid Metabolism ◽

Control Analysis ◽

Computational Systems Biology ◽

Metabolic Pathway Analysis ◽

Drug Target Identification ◽

Computational Systems

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Integration of lipidomics and transcriptomics data towards a systems biology model of sphingolipid metabolism

BMC Systems Biology ◽

10.1186/1752-0509-5-26 ◽

2011 ◽

Vol 5 (1) ◽

pp. 26 ◽

Cited By ~ 36

Author(s):

Shakti Gupta ◽

Mano R Maurya ◽

Alfred H Merrill Jr ◽

Christopher K Glass ◽

Shankar Subramaniam

Keyword(s):

Systems Biology ◽

Sphingolipid Metabolism ◽

Transcriptomics Data

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Combining integrated systems-biology approaches with intervention-based experimental design provides a higher-resolution path forward for microbiome research

Behavioral and Brain Sciences ◽

10.1017/s0140525x18002911 ◽

2019 ◽

Vol 42 ◽

Author(s):

J. Alfredo Blakeley-Ruiz ◽

Carlee S. McClintock ◽

Ralph Lydic ◽

Helen A. Baghdoyan ◽

James J. Choo ◽

...

Keyword(s):

Systems Biology ◽

High Resolution ◽

Experimental Design ◽

Integrated Systems ◽

Microbiome Research ◽

Constructive Criticism

Abstract The Hooks et al. review of microbiota-gut-brain (MGB) literature provides a constructive criticism of the general approaches encompassing MGB research. This commentary extends their review by: (a) highlighting capabilities of advanced systems-biology “-omics” techniques for microbiome research and (b) recommending that combining these high-resolution techniques with intervention-based experimental design may be the path forward for future MGB research.

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