scholarly journals Rapid fabrication of nickel molds for prototyping embossed plastic microfluidic devices

Lab on a Chip ◽  
2013 ◽  
Vol 13 (8) ◽  
pp. 1468 ◽  
Author(s):  
Richard Novak ◽  
Navpreet Ranu ◽  
Richard A. Mathies
2019 ◽  
Vol 3 (1) ◽  
pp. 26 ◽  
Author(s):  
Mohamed Mohamed ◽  
Hitendra Kumar ◽  
Zongjie Wang ◽  
Nicholas Martin ◽  
Barry Mills ◽  
...  

With the dramatic increment of complexity, more microfluidic devices require 3D structures, such as multi-depth and -layer channels. The traditional multi-step photolithography is time-consuming and labor-intensive and also requires precise alignment during the fabrication of microfluidic devices. Here, we present an inexpensive, single-step, and rapid fabrication method for multi-depth microfluidic devices using a high-resolution liquid crystal display (LCD) stereolithographic (SLA) three-dimensional (3D) printing system. With the pixel size down to 47.25 μm, the feature resolutions in the horizontal and vertical directions are 150 μm and 50 μm, respectively. The multi-depth molds were successfully printed at the same time and the multi-depth features were transferred properly to the polydimethylsiloxane (PDMS) having multi-depth channels via soft lithography. A flow-focusing droplet generator with a multi-depth channel was fabricated using the presented 3D printing method. Experimental results show that the multi-depth channel could manipulate the morphology and size of droplets, which is desired for many engineering applications. Taken together, LCD SLA 3D printing is an excellent alternative method to the multi-step photolithography for the fabrication of multi-depth microfluidic devices. Taking the advantages of its controllability, cost-effectiveness, and acceptable resolution, LCD SLA 3D printing can have a great potential to fabricate 3D microfluidic devices.


Lab on a Chip ◽  
2001 ◽  
Vol 1 (1) ◽  
pp. 7-9 ◽  
Author(s):  
Aimin Tan ◽  
Kenneth Rodgers ◽  
John P. Murrihy ◽  
Cian O’Mathuna ◽  
Jeremy D. Glennon

Lab on a Chip ◽  
2013 ◽  
Vol 13 (15) ◽  
pp. 2922 ◽  
Author(s):  
Ana C. Glavan ◽  
Ramses V. Martinez ◽  
E. Jane Maxwell ◽  
Anand Bala Subramaniam ◽  
Rui M. D. Nunes ◽  
...  

2014 ◽  
Vol 881-883 ◽  
pp. 503-508 ◽  
Author(s):  
Cai Bin Zhou ◽  
Yun Zhang ◽  
Shang Wang Le ◽  
Jin Fang Nie ◽  
Ting Zhang ◽  
...  

In this paper, we initially report a new type of wax printing method for rapid fabrication of microfluidic devices in paper using a commercially available, cheap, minitype (home-use) CO2laser engraving machine. This method combines the two core operations commonly involved in all previous wax printing methods, namely the printing and heating (melting) of wax patterns into one operation of engraving home-made wax slice (put in contact with the surface of paper) by laser. The heat produced by the laser makes the wax being engraved melt and then spread into paper to form complete hydrophobic barriers which are used to define the hydrophilic flow channels or separate test microzones. Under the optimized experimental conditions, a typical device on a 3 cm × 3 cm piece of paper could be fabricated separately within ~320 sec and is ready for use once the engraving process is completed. The fabrication resolution and multiplexed analytical capability of the wax-patterned paper were additionally characterized.


2020 ◽  
Vol 45 (14) ◽  
pp. 3929
Author(s):  
Chenchu Zhang ◽  
Jianming Zhang ◽  
Renfei Chen ◽  
Jiawen Li ◽  
Chaowei Wang ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document