Role of endothelial cell membrane transport in red wine polyphenols-induced coronary vasorelaxation: involvement of bilitranslocase

2013 ◽  
Vol 4 (10) ◽  
pp. 1452 ◽  
Author(s):  
Lovro Ziberna ◽  
Jong-Hun Kim ◽  
Cyril Auger ◽  
Sabina Passamonti ◽  
Valérie Schini-Kerth
Keyword(s):  
Endothelial Cell ◽  
Cell Membrane ◽  
Membrane Transport ◽  
Red Wine ◽  
Wine Polyphenols ◽  
Red Wine Polyphenols ◽  
Cell Membrane Transport

The Role of MIP in Lens Fiber Cell Membrane Transport

1999 ◽  
Vol 170 (3) ◽  
pp. 191-203 ◽  
Author(s):  
K. Varadaraj ◽  
C. Kushmerick ◽  
G.J. Baldo ◽  
S. Bassnett ◽  
A. Shiels ◽  
...  
Keyword(s):  
Cell Membrane ◽  
Membrane Transport ◽  
Fiber Cell ◽  
Lens Fiber ◽  
Lens Fiber Cell ◽  
Cell Membrane Transport

scholarly journals The Pro-Oxidant Activity of Red Wine Polyphenols Induces an Adaptive Antioxidant Response in Human Erythrocytes

Antioxidants ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 800
Author(s):  
Idolo Tedesco ◽  
Carmela Spagnuolo ◽  
Gian Luigi Russo ◽  
Maria Russo ◽  
Carmen Cervellera ◽  
...  
Keyword(s):  
Red Wine ◽  
Redox System ◽  
Underlying Mechanism ◽  
Antioxidant Response ◽  
Human Erythrocytes ◽  
Wine Polyphenols ◽  
Red Wine Polyphenols ◽  
Glucose 6 Phosphate Dehydrogenase ◽  
Oxidant Effect

The protective effect of dealcoholized red wine on human health has been partially associated with its polyphenolic components, suggesting that the pool of polyphenols, including flavonoids and anthocyanins, can be responsible for the functional effects of this beverage. We hypothesize a new role of red wine polyphenols (RWp) in modulating the antioxidant potential of erythrocytes, protecting them against oxidative stress. We previously demonstrated that RWp activated the Plasma Membrane Redox System (PMRS), which is involved in neutralizing plasma free radicals. Here, we investigated the underlying mechanism triggered by RWp in the activation of PMRS via the involvement of GSH. Hence, treatment of human erythrocytes with RWp (73 μg/mL Gallic Acid Equivalents) increased GSH intracellular concentration, which depends upon the activation of glutathione reductase (GR) and glucose-6-phosphate dehydrogenase (G6PD), whose enzymatic activities increase of about 30% and 47%, respectively. Changes in the GSH pathway induced by RWp were associated with a slight but significant increase in reactive oxygen species (ROS). We conclude that the pro-oxidant effect of RWp promoted an adaptive stress response in human erythrocytes, which enhances their antioxidant defense.

Role of gender and estrogen receptors in the rat aorta endothelium-dependent relaxation to red wine polyphenols

2009 ◽  
Vol 51 (2-3) ◽  
pp. 140-146 ◽  
Author(s):  
Modou Oumy Kane ◽  
Eric Anselm ◽  
Yanna Dantas Rattmann ◽  
Cyril Auger ◽  
Valérie B. Schini-Kerth
Keyword(s):  
Estrogen Receptors ◽  
Red Wine ◽  
Rat Aorta ◽  
Wine Polyphenols ◽  
Red Wine Polyphenols ◽  
Endothelium Dependent Relaxation
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