Efficient cyanoaromatic photosensitizers for singlet oxygen production: synthesis and characterization of the transient reactive species

2013 ◽  
Vol 15 (40) ◽  
pp. 17219 ◽  
Author(s):  
Filippo Ronzani ◽  
Emmanuel Arzoumanian ◽  
Sylvie Blanc ◽  
Patrice Bordat ◽  
Thierry Pigot ◽  
...  
Keyword(s):  
Singlet Oxygen ◽  
Reactive Species ◽  
Synthesis And Characterization ◽  
Oxygen Production

Synthesis and characterization of novel 5-monocarbohydrate-10,20-bis-aryl-porphyrins

2020 ◽  
Vol 24 (01n03) ◽  
pp. 330-339
Author(s):  
Flávio Figueira ◽  
Leandro M. O. Lourenço ◽  
Maria G. P. M. S. Neves ◽  
José A. S. Cavaleiro ◽  
João P. C. Tomé
Keyword(s):  
Singlet Oxygen ◽  
Synthesis And Characterization ◽  
Spectroscopic Techniques ◽  
Oxygen Production ◽  
Porphyrin Derivatives ◽  
Porphyrin Macrocycle ◽  
Meso Position

The synthesis of derivatives bearing glucose or galactose units linked by an acrylate spacer to one free meso position of a bis-aryl-porphyrin macrocycle was developed and characterized by standard spectroscopic techniques. The new mono-substituted gluco- and galacto-porphyrin derivatives 5–8 present an alternative to the widespread tetra-aryl porphyrin functionalization. Singlet oxygen studies showed a comparable singlet oxygen production with TPP. Furthermore, the less bulky architectures here synthesized present an opportunity to enhance the PDT and PDI capabilities of glycoporphyrins with a simple synthetic modification at one of the meso positions.

New peripherally substituted lutetium mono and bis phthalocyanines: Synthesis and comparative photophysical and photochemical properties

2019 ◽  
Vol 23 (11n12) ◽  
pp. 1542-1550
Author(s):  
Nagihan Kocaağa ◽  
Öznur Dülger Kutlu ◽  
Ali Erdoğmuş
Keyword(s):  
Mass Spectrometry ◽  
Photodynamic Therapy ◽  
Singlet Oxygen ◽  
Photophysical Properties ◽  
Quantum Yields ◽  
Synthesis And Characterization ◽  
Type Ii ◽  
H Nmr ◽  
Photochemical Properties

In this study, the synthesis and characterization of mono-(phthalocyaninato) lutetium(III) (1-Cl and 1-F) [Lu[Formula: see text](AcO)(Pc)] (Pc [Formula: see text] phthalocyaninato, AcO [Formula: see text] acetate) and bis-(phthalocyaninato) lutetium(III) (2-Cl and 2-Br) [Lu[Formula: see text]Pc[Formula: see text]] bearing halogenated (F, Cl and Br) phenoxy–phenoxy groups are described and verified by IR, [Formula: see text]H-NMR, UV-vis and mass spectrometry. Photochemical and photophysical properties of 1-F, 1-Cl 2-Cl and 2-Br in DMSO are also presented. A comparison between photophysical and photochemical parameters of mono and bis derivatives showed that mono phthalocyanines are better photosensitizers than bis phthalocyanines. Photophysical and photochemical properties of phthalocyanines are very useful for photodynamic therapy applications. Singlet oxygen quantum yields [Formula: see text] give an indication of the potential of the complexes as photosensitizers in photodynamic therapy applications. The chloro, fluoro, bromo-phenoxy–phenoxy substituted mono-(phthalocyaninato) lutetium(III) complexes (1-Cl and 1-F) gave good singlet oxygen quantum yields (from 0.86 to 0.80) in DMSO. Thus, these complexes show potential as Type II photosensitizers for PDT of cancer.

Synthesis and characterization of novel 7-oxy-3-ethyl-6-hexyl-4-methylcoumarin substituted metallo phthalocyanines and investigation of their photophysical and photochemical properties

2019 ◽  
Vol 48 (34) ◽  
pp. 13046-13056 ◽  
Author(s):  
Mücahit Özdemir ◽  
Begümhan Karapınar ◽  
Bahattin Yalçın ◽  
Ümit Salan ◽  
Mahmut Durmuş ◽  
...  
Keyword(s):  
Singlet Oxygen ◽  
Quantum Yields ◽  
Synthesis And Characterization ◽  
Photochemical Properties ◽  
Lipophilic Groups

Coumarin functionalized metallo phthalocyanines shows increased singlet oxygen quantum yields when included lipophilic groups.

Synthesis and Characterization of Water-Soluble Phenylene−Vinylene-Based Singlet Oxygen Sensitizers for Two-Photon Excitation

2005 ◽  
Vol 70 (18) ◽  
pp. 7065-7079 ◽  
Author(s):  
Christian B. Nielsen ◽  
Mette Johnsen ◽  
Jacob Arnbjerg ◽  
Michael Pittelkow ◽  
Sean P. McIlroy ◽  
...  
Keyword(s):  
Singlet Oxygen ◽  
Water Soluble ◽  
Synthesis And Characterization ◽  
Phenylene Vinylene ◽  
Two Photon ◽  
Photon Excitation ◽  
Two Photon Excitation

Synthesis and Characterization of New Fluorene-Based Singlet Oxygen Sensitizers

2005 ◽  
Vol 16 (1) ◽  
pp. 105-110 ◽  
Author(s):  
Kevin D. Belfield ◽  
Claudia C. Corredor ◽  
Alma R. Morales ◽  
Marie A. Dessources ◽  
Florencio E. Hernandez
Keyword(s):  
Singlet Oxygen ◽  
Synthesis And Characterization

Methylthio BODIPY as a standard triplet photosensitizer for singlet oxygen production: a photophysical study

2019 ◽  
Vol 21 (36) ◽  
pp. 20403-20414 ◽  
Author(s):  
Ruth Prieto-Montero ◽  
Rebeca Sola-Llano ◽  
Raul Montero ◽  
Asier Longarte ◽  
Teresa Arbeloa ◽  
...  
Keyword(s):  
Singlet Oxygen ◽  
Singlet State ◽  
Oxygen Production ◽  
Photophysical Study

The detailed triplet and singlet state characterization of 3,5-dimethyl-2,6-diiodo-8-thiomethyl-pyrromethene (MeSBDP), a promising standard sensitizer for singlet oxygen production.

Octa-substituted metallophthalocyanines bearing (2,3-dihydrobenzo-1,4-benzodioxin-2-yl)methoxy and chloro groups: Synthesis, characterization and photophysicochemical studies

2020 ◽  
Vol 24 (04) ◽  
pp. 548-562 ◽  
Author(s):  
Semih Gorduk
Keyword(s):  
Quantum Yield ◽  
Singlet Oxygen ◽  
Synthesis And Characterization ◽  
Different Types ◽  
Ft Ir ◽  
Yield Values ◽  
Characterization Studies ◽  
First Time ◽  
Potential Use

In this study, the synthesis and characterization of novel 4-chloro-5-((2,3-dihydrobenzo-1,4-benzodioxin-2-yl)methoxy)phthalonitrile (1) and its peripherally octa-substituted Zn(II) (Pc-Zn), In(III) (PcInCI) and Mg(II) (Pc-Mg) phthalocyanine (Pc) derivatives are reported for the first time. FT-IR, elemental analysis, UV-vis, NMR and MS techniques were used for characterization studies of the compounds. Aggregation properties of the compounds were evaluated in DMF, DMSO and THF solvents in different concentrations, and the compounds did not tend to aggregate in these solvents. In addition, photophysicochemical properties such as fluorescence, photodegradation and singlet oxygen quantum yield of the compounds were examined in DMSO, DMF and THF solvents to show the potential use of these novel compounds as photosensitizers for photodynamic therapy (PDT). The effects of zinc, indium and magnesium metals, octa substitutions in peripheral positions and different types of solvents on photophysicochemical properties were investigated. The singlet oxygen quantum yield values of compounds ranged from 0.27 to 0.77 in different solvents. As a result of the photophysicochemical properties, these compounds can be considered as potential candidates for PDT, applications.

Sign in / Sign up

Export Citation Format

Share Document