Electronic structure analysis of multistate reactivity in transition metal catalyzed reactions: the case of C–H bond activation by non-heme iron(iv)–oxo cores

2013 ◽  
Vol 15 (21) ◽  
pp. 8017 ◽  
Author(s):  
Shengfa Ye ◽  
Cai-Yun Geng ◽  
Sason Shaik ◽  
Frank Neese
Keyword(s):  
Electronic Structure ◽  
Transition Metal ◽  
Structure Analysis ◽  
Bond Activation ◽  
Heme Iron ◽  
Non Heme Iron ◽  
Transition Metal Catalyzed ◽  
Catalyzed Reactions ◽  
Metal Catalyzed

Transition Metal Catalyzed C-H bond Activation/Functionalization and Annulation of Phthalazinones

2021 ◽  
Author(s):  
Chandrasekaran Sivaraj ◽  
Alagumalai Ramkumar ◽  
Nagesh Sankaran ◽  
THIRUMANAVELAN GANDHI
Keyword(s):  
Natural Products ◽  
Transition Metal ◽  
Bond Activation ◽  
Bioactive Molecules ◽  
Structural Motifs ◽  
The Past ◽  
Transition Metal Catalyzed ◽  
Catalyzed Reactions ◽  
Metal Catalyzed

Phthalazinones and their higher congeners are commonly prevalent structural motifs that occur in natural products, bioactive molecules, and pharmaceuticals. In the past few decades transition metal-catalyzed reactions have received an...

Monodentate Trialkylphosphines: Privileged Ligands in Metal-catalyzed Crosscoupling Reactions

2020 ◽  
Vol 24 (3) ◽  
pp. 231-264 ◽  
Author(s):  
Kevin H. Shaughnessy
Keyword(s):  
Transition Metal ◽  
Cross Coupling ◽  
Coupling Reactions ◽  
Cross Coupling Reactions ◽  
Aryl Bromides ◽  
Wide Range ◽  
Sterically Demanding ◽  
Transition Metal Catalyzed ◽  
Catalyzed Reactions ◽  
Metal Catalyzed

Phosphines are widely used ligands in transition metal-catalyzed reactions. Arylphosphines, such as triphenylphosphine, were among the first phosphines to show broad utility in catalysis. Beginning in the late 1990s, sterically demanding and electronrich trialkylphosphines began to receive attention as supporting ligands. These ligands were found to be particularly effective at promoting oxidative addition in cross-coupling of aryl halides. With electron-rich, sterically demanding ligands, such as tri-tertbutylphosphine, coupling of aryl bromides could be achieved at room temperature. More importantly, the less reactive, but more broadly available, aryl chlorides became accessible substrates. Tri-tert-butylphosphine has become a privileged ligand that has found application in a wide range of late transition-metal catalyzed coupling reactions. This success has led to the use of numerous monodentate trialkylphosphines in cross-coupling reactions. This review will discuss the general properties and features of monodentate trialkylphosphines and their application in cross-coupling reactions of C–X and C–H bonds.

Transition-Metal-Catalyzed Oxidative and Decarboxylative Acylations through sp2 C-H Bond Activation

2015 ◽  
Vol 20 (5) ◽  
pp. 471-511 ◽  
Author(s):  
Satyasheel Sharma ◽  
Neeraj Kumar Mishra ◽  
Youngmi Shin ◽  
In Su Kim
Keyword(s):  
Transition Metal ◽  
Bond Activation ◽  
Transition Metal Catalyzed ◽  
Metal Catalyzed

Chemistry of Unsymmetrical C1-Substituted Oxabenzonorbornadienes

2021 ◽  
Vol 17 ◽  
Author(s):  
Austin Pounder ◽  
Angel Ho ◽  
Matthew Macleod ◽  
William Tam
Keyword(s):  
Transition Metal ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Substituent Effects ◽  
Face Selectivity ◽  
Transition Metal Catalyzed ◽  
Catalyzed Reactions ◽  
Metal Catalyzed ◽  
Synthetic Intermediate

: Oxabenzonorbornadiene (OBD) is a useful synthetic intermediate which can be readily activated by transition metal complexes with great face selectivity due to its dual-faced nature and intrinsic angle strain on the alkene. To date, the understanding of transition-metal catalyzed reactions of OBD itself has burgeoned; however, this has not been the case for unsymmetrical OBDs. Throughout the development of these reactions, the nature of C1-substituent has proven to have a profound effect on both the reactivity and selectivity of the outcome of the reaction. Upon substitution, different modes of reactivity arise, contributing to the possibility of multiple stereo-, regio-, and in extreme cases, constitutional isomers which can provide unique means of constructing a variety of synthetically useful cyclic frameworks. To maximize selectivity, an understanding of bridgehead substituent effects is crucial. To that end, this review outlines hitherto reported examples of bridgehead substituent effects on the chemistry of unsymmetrical C1-substituted OBDs.

scholarly journals Transition metal-catalyzed reactions of N-sulfinyl imines

2021 ◽  
pp. 153104
Author(s):  
Francisco Foubelo ◽  
Carmen Nájera ◽  
José M. Sansano ◽  
Miguel Yus
Keyword(s):  
Transition Metal ◽  
Transition Metal Catalyzed ◽  
Catalyzed Reactions ◽  
Metal Catalyzed

Iodide effects in transition metal catalyzed reactions

2004 ◽  
pp. 3409 ◽  
Author(s):  
Peter M. Maitlis ◽  
Anthony Haynes ◽  
Brian R. James ◽  
Marta Catellani ◽  
Gian Paolo Chiusoli
Keyword(s):  
Transition Metal ◽  
Transition Metal Catalyzed ◽  
Catalyzed Reactions ◽  
Metal Catalyzed

Transition metal-catalyzed arylation of unstrained C−C single bonds

2021 ◽  
Author(s):  
Long Yang ◽  
Wuxin Zhou ◽  
Qiang Li ◽  
Xiangge Zhou
Keyword(s):  
Organic Chemistry ◽  
Transition Metal ◽  
Bond Activation ◽  
Important Research ◽  
Carbon Bond ◽  
Research Areas ◽  
Carbon Carbon Bond ◽  
Transition Metal Catalyzed ◽  
Metal Catalyzed ◽  
Single Bonds

Carbon−carbon bond activation is one of the most challenging and important research areas in organic chemistry. Selective C−C bond activation of unstrained substrates is difficult to achieve owing to its...

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