Stabilized Wittig olefination for bioconjugation

2013 ◽  
Vol 49 (95) ◽  
pp. 11188 ◽  
Author(s):  
Kenneth M. Lum ◽  
Vanessa J. Xavier ◽  
Michelle J.-H. Ong ◽  
Charles W. Johannes ◽  
Kok-Ping Chan
Keyword(s):  
Wittig Olefination

scholarly journals Xylochemical Synthesis and Biological Evaluation of Shancigusin C and Bletistrin G

Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3224
Author(s):  
Leander Geske ◽  
Ulrich Kauhl ◽  
Mohamed E. M. Saeed ◽  
Anja Schüffler ◽  
Eckhard Thines ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Biological Activities ◽  
Biological Evaluation ◽  
Aromatic Substitution ◽  
Substitution Reactions ◽  
Total Syntheses ◽  
Wittig Olefination ◽  
Starting Point ◽  
Perkin Reaction ◽  
Synthesis And Biological Evaluation

The biological activities of shancigusin C (1) and bletistrin G (2), natural products isolated from orchids, are reported along with their first total syntheses. The total synthesis of shancigusin C (1) was conducted by employing the Perkin reaction to forge the central stilbene core, whereas the synthesis of bletistrin G (2) was achieved by the Wittig olefination followed by several regioselective aromatic substitution reactions. Both syntheses were completed by applying only renewable starting materials according to the principles of xylochemistry. The cytotoxic properties of shancigusin C (1) and bletistrin G (2) against tumor cells suggest suitability as a starting point for further structural variation.

scholarly journals Combining Wittig Olefination with Photoassisted Domino Reaction To Distinguish 5-Formylcytosine from 5-Formyluracil

2019 ◽  
Vol 91 (15) ◽  
pp. 9366-9370 ◽  
Author(s):  
Qian Zhou ◽  
Kun Li ◽  
Ling-Ling Li ◽  
Kang-Kang Yu ◽  
Hong Zhang ◽  
...  
Keyword(s):  
Domino Reaction ◽  
Wittig Olefination

2-Alkenylphosphonates and PO-Ylids Derived Thereof in trans Selective Horner-Wittig Olefination Reactions

Synlett ◽  
1996 ◽  
Vol 1996 (12) ◽  
pp. 1197-1198 ◽  
Author(s):  
Rong-qiang Liu ◽  
Manfred Schlosser
Keyword(s):  
Wittig Olefination ◽  
In Trans ◽  
Olefination Reactions

Wittig Olefination–Claisen Rearrangement Protocol for Cyclohexene Annulation

2010 ◽  
Vol 40 (3) ◽  
pp. 423-433 ◽  
Author(s):  
Mukund G. Kulkarni ◽  
Dnyaneshwar D. Gaikwad ◽  
Ajit S. Borhade ◽  
Yunus B. Shaikh ◽  
Vijay B. Ningdale ◽  
...  
Keyword(s):  
Claisen Rearrangement ◽  
Wittig Olefination

Isolation, identification, synthesis, and bioefficacy of female Diacrisia obliqua (Arctiidae) sex pheromone blend. An Indian agricultural pest

2001 ◽  
Vol 73 (7) ◽  
pp. 1157-1162 ◽  
Author(s):  
J. S. Yadav ◽  
M. Y. Valli ◽  
A. R. Prasad
Keyword(s):  
Sex Pheromone ◽  
Female Sex Pheromone ◽  
Wittig Olefination ◽  
Pheromone Components ◽  
Diacrisia Obliqua ◽  
Seed Crops ◽  
Key Steps ◽  
Sex Pheromone Blend ◽  
Pheromone Blend ◽  
Oil Seed Crops

Diacrisia obliqua is a polyphagous pest especially on oil seed crops. Adult female sex pheromone blend consists of five pheromone components, which include (3Z,6Z)-cis-9,10-epoxyl,3,6-henicosatriene and (3Z,6Z)-cis-9,10-epoxy3,6-henicosadiene. Synthesis of these enantiomers was achieved through alkylative epoxide rearrangement and stereoselective Wittig olefination reactions as key steps. Bioefficacy experiments both at laboratory and minifield were very positive.

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