Single-crystal caged gold nanorods with tunable broadband plasmon resonances

2013 ◽  
Vol 49 (83) ◽  
pp. 9630 ◽  
Author(s):  
Wei Xiong ◽  
Debabrata Sikdar ◽  
Michael Walsh ◽  
Kae Jye Si ◽  
Yue Tang ◽  
...  
2018 ◽  
Vol 19 (11) ◽  
pp. 3318 ◽  
Author(s):  
Oscar Knights ◽  
James McLaughlan

Gold nanorods (AuNRs) have the potential to be used in photoacoustic (PA) imaging and plasmonic photothermal therapy (PPTT) due to their unique optical properties, biocompatibility, controlled synthesis, and tuneable surface plasmon resonances (SPRs). Conventionally, continuous-wave (CW) lasers are used in PPTT partly due to their small size and low cost. However, if pulsed-wave (PW) lasers could be used to destroy tissue then combined theranostic applications, such as PA-guided PPTT, would be possible using the same laser system and AuNRs. In this study, we present the effects of AuNR size on PA response, PW-PPTT efficacy, and PA imaging in a tissue-mimicking phantom, as a necessary step in the development of AuNRs towards clinical use. At equivalent NP/mL, the PA signal intensity scaled with AuNR size, indicating that overall mass has an effect on PA response, and reinforcing the importance of efficient tumour targeting. Under PW illumination, all AuNRs showed toxicity at a laser fluence below the maximum permissible exposure to skin, with a maximum of 80% cell-death exhibited by the smallest AuNRs, strengthening the feasibility of PW-PPTT. The theranostic potential of PW lasers combined with AuNRs has been demonstrated for application in the lung.


2006 ◽  
Author(s):  
Matthew Pelton ◽  
Mingzhao Liu ◽  
Hee Y. Kim ◽  
Glenna Smith ◽  
Philippe Guyot-Sionnest ◽  
...  

2009 ◽  
Vol 80 (11) ◽  
Author(s):  
Moussa N’Gom ◽  
Shuzhou Li ◽  
George Schatz ◽  
Rolf Erni ◽  
Ashish Agarwal ◽  
...  

2006 ◽  
Vol 31 (13) ◽  
pp. 2075 ◽  
Author(s):  
Matthew Pelton ◽  
Mingzhao Liu ◽  
Hee Y. Kim ◽  
Glenna Smith ◽  
Philippe Guyot-Sionnest ◽  
...  

2012 ◽  
Vol 22 (45) ◽  
pp. 24006 ◽  
Author(s):  
Peijie Wang ◽  
Mingyue Liu ◽  
Geli Gao ◽  
Shunping Zhang ◽  
Honglong Shi ◽  
...  

2018 ◽  
Vol 54 (24) ◽  
pp. 3022-3025 ◽  
Author(s):  
Wenming Tong ◽  
Hadas Katz-Boon ◽  
Michael J. Walsh ◽  
Matthew Weyland ◽  
Joanne Etheridge ◽  
...  

The transformation of single crystal gold nanorods over extended growth times shows smoothing of surface morphology and reduction and convergence of aspect ratios across AgNO3 concentrations. The final aspect ratio has little dependence on the AgNO3 concentration.


Science ◽  
2017 ◽  
Vol 358 (6363) ◽  
pp. 640-644 ◽  
Author(s):  
Guillermo González-Rubio ◽  
Pablo Díaz-Núñez ◽  
Antonio Rivera ◽  
Alejandro Prada ◽  
Gloria Tardajos ◽  
...  

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